Protein
Histamine N-methyltransferase B
Function
Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family.
Sequence
MDSGLRSLLSDHSRYVESFRLFLQNSTEHQCMQHFIETKLPDIISSIGNDKPVIDVLGIGSGSGEIDLQMIAKIQARWPGVSINNQIVEPSAEQILGYKERVAKAPNLGYVTFSWHHQTSSEFEHRVTEDKQMTKYDFIHMIQMLYYVKDVPGTLKFFKSCLAPNGKLLIILVSGNSGWAPLWKKYGQRLPLNDLCLYVTAGDIAEMLSSMGARFQSHELQSDMDITKCFIEGDKNGELLLDFLTETCDFRKNAPAELRDQIICDLKSPRCSTTKDGKVIFNNNLSVIVVEAD