About Services Plasmids Contact

hmpA

Gene
hmpA
Protein
Flavohemoprotein
Organism
Giardia intestinalis (strain ATCC 50581 / GS clone H7)
Length
458 amino acids
Function
Flavohemoprotein involved in nitric oxide (NO) detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the protozoan parasite from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress. May also be involved in O(2) detoxification (By similarity).
Similarity
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Mass
51.33 kDa
Sequence
MPLSEDTIKAVEATADLVAAQGLDFTRAFYERMLTRNEELKDVFNLSHQRDLRQPKALLDSLVAYARSIRKINELHELQEQGLPVPAERLAELQGFFAVAERIAHKHASVGIQPAQYQIVGAHLLATIEERVTADKAILAAWSKAYDFLAHLFVRREEEIYTETESSEGGWRQTRSFRVEEKAQITERIFRFRLVPAEKGTAVALHKPGQYLAVFVRDPRLSPHRQIRQYSITSAPNHTYYEIAVHRDKQATVSGYLHDHVAVGDLLKLAPPYGDFFLEYREPGGQAADGQPSPEPLALHGGAVNFAAERMTPIVLISGGIGQTPLLSILRFLAEKEGQAAIRPIFWIHAAHDSRARAFKAEVDAIKVTDLPGLRTTTFLSEVDETMDKKGEDYDFAGRISLDRVPGLAELEADGANPHYFFVGPAGFMVAVEQQLKAWSVPEDRIHFEMFGPFKPLQ

Gene
hmpA
Protein
Flavohemoprotein
Organism
Giardia intestinalis (strain ATCC 50803 / WB clone C6)
Length
458 amino acids
Function
Flavohemoprotein involved in nitric oxide (NO) detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the protozoan parasite from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress. May also be involved in O(2) detoxification.
Similarity
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Mass
52.003 kDa
Sequence
MTLSEDTLRAVEATAGLIAAQGIEFTRAFYERMLTKNEELKNIFNLAHQRTLRQPKALLDSLVAYALNIRRINELYELKGKGLPVPPEHWAELQGFFSAAERVANKHTSFGIQPAQYQIVGAHLLATIEDRITKDKDILAEWAKAYQFLADLFIKREEEIYAATEGCKGGWRQTRTFRVEEKTRVNEIICKFRLVPAEEGAGVVEHRPGQYLAIFVRSPEHFQHQQIRQYSIISAPNSAYYEIAVHRDEKGTVSRYLHDYVSTGDLLEVAPPYGDFFLRYLEADEQAPADTQASQEFQMLQSGAINFAAEKTMPIVLISGGIGQTPLLSMLRFLAQKEGKETARPIFWIHAAHNSRVRAFKEEVDAIRETALPSLRVVTFLSEVRATDREGEDYDFAGRINLDRISELTKLEADNANPHYFFVGPTGFMTAVEEQLKTKSVPNSRIHFEMFGPFKASH

Gene
hmpA
Protein
Flavohemoprotein
Organism
Giardia intestinalis (strain ATCC 50581 / GS clone H7)
Length
458 amino acids
Function
Flavohemoprotein involved in nitric oxide (NO) detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the protozoan parasite from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress. May also be involved in O(2) detoxification (By similarity).
Similarity
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Mass
51.33 kDa
Sequence
MPLSEDTIKAVEATADLVAAQGLDFTRAFYERMLTRNEELKDVFNLSHQRDLRQPKALLDSLVAYARSIRKINELHELQEQGLPVPAERLAELQGFFAVAERIAHKHASVGIQPAQYQIVGAHLLATIEERVTADKAILAAWSKAYDFLAHLFVRREEEIYTETESSEGGWRQTRSFRVEEKAQITERIFRFRLVPAEKGTAVALHKPGQYLAVFVRDPRLSPHRQIRQYSITSAPNHTYYEIAVHRDKQATVSGYLHDHVAVGDLLKLAPPYGDFFLEYREPGGQAADGQPSPEPLALHGGAVNFAAERMTPIVLISGGIGQTPLLSILRFLAEKEGQAAIRPIFWIHAAHDSRARAFKAEVDAIKVTDLPGLRTTTFLSEVDETMDKKGEDYDFAGRISLDRVPGLAELEADGANPHYFFVGPAGFMVAVEQQLKAWSVPEDRIHFEMFGPFKPLQ

Gene
hmpA
Protein
Flavohemoprotein
Organism
Giardia intestinalis (strain ATCC 50803 / WB clone C6)
Length
458 amino acids
Function
Flavohemoprotein involved in nitric oxide (NO) detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the protozoan parasite from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress. May also be involved in O(2) detoxification.
Similarity
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Mass
52.003 kDa
Sequence
MTLSEDTLRAVEATAGLIAAQGIEFTRAFYERMLTKNEELKNIFNLAHQRTLRQPKALLDSLVAYALNIRRINELYELKGKGLPVPPEHWAELQGFFSAAERVANKHTSFGIQPAQYQIVGAHLLATIEDRITKDKDILAEWAKAYQFLADLFIKREEEIYAATEGCKGGWRQTRTFRVEEKTRVNEIICKFRLVPAEEGAGVVEHRPGQYLAIFVRSPEHFQHQQIRQYSIISAPNSAYYEIAVHRDEKGTVSRYLHDYVSTGDLLEVAPPYGDFFLRYLEADEQAPADTQASQEFQMLQSGAINFAAEKTMPIVLISGGIGQTPLLSMLRFLAQKEGKETARPIFWIHAAHNSRVRAFKEEVDAIRETALPSLRVVTFLSEVRATDREGEDYDFAGRINLDRISELTKLEADNANPHYFFVGPTGFMTAVEEQLKTKSVPNSRIHFEMFGPFKASH