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hisH

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Corynebacterium jeikeium (strain K411)
Length
242 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
26.007 kDa
Sequence
MNSSLSSRRPHVALLDYGSGNVRSAQRAVERAGAEVEVTRDPETVQRADGLLVPGVGAYSACMKQLHSVYGDRLIGQRLAGGRPVLGICVGMQILFDRGVEFAEGTGEAGAGEAAFTEGMGEWPGTVEKLDADVLPHMGWNTVEVGDGSSASALGKPAAEPTKMFAGIEETERFYFVHSYGVQEWELLTDGRTEPPLVHWASHGRSRFVAAVENGPLWATQFHPEKSGDAGLKLLQNWVDTL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
Length
232 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
24.699 kDa
Sequence
MSVRQTTADVVVVDYGLGNLRSVTRGLERAGANVSLSEDPAEFDAADGIVLPGVGAFSEGMDNAGPFREALVEQAEAGKPLFGICLGMQMLLTTSEEADHEGQGDAEGLDLIPGKNVRFSRDQTVPHMGWNELDVTRDHPLVEGVDSVGSKTPRADGTGGSVDGEHAYFVHSYYAVPDDESATVATTDYGTDFASIVANDAGNVFGTQFHPEKSGETGLRILRNYVDYCLDH

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
Length
232 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
24.699 kDa
Sequence
MSVRQTTADVVVVDYGLGNLRSVTRGLERAGANVSLSEDPAEFDAADGIVLPGVGAFSEGMDNAGPFREALVEQAEAGKPLFGICLGMQMLLTTSEEADHEGQGDAEGLDLIPGKNVRFSRDQTVPHMGWNELDVTRDHPLVEGVDSVGSKTPRADGTGGSVDGEHAYFVHSYYAVPDDESATVATTDYGTDFASIVANDAGNVFGTQFHPEKSGETGLRILRNYVDYCLDH

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thiobacillus denitrificans (strain ATCC 25259)
Length
228 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
24.508 kDa
Sequence
MSVDIAVVDYGMGNLRSVSKAIEHVAPSATVVVTSSPDVIAEAGRVVFPGQGAARDCMREIDARGLREAIATAARSKPFLGICMGMQVLFEHSEEGDTACLGILPGNVQRFPHEAMHDDRGNKLKVPHMGWNNVHQGAPHPLWSGIEDGERFYFVHSYFVQPTTPDLIAGFSHYPFPFTCAVASGNIFAVQFHPEKSQNAGLTLLGNFVTWNPGEHASACDLSGASCA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thiobacillus denitrificans (strain ATCC 25259)
Length
228 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
24.508 kDa
Sequence
MSVDIAVVDYGMGNLRSVSKAIEHVAPSATVVVTSSPDVIAEAGRVVFPGQGAARDCMREIDARGLREAIATAARSKPFLGICMGMQVLFEHSEEGDTACLGILPGNVQRFPHEAMHDDRGNKLKVPHMGWNNVHQGAPHPLWSGIEDGERFYFVHSYFVQPTTPDLIAGFSHYPFPFTCAVASGNIFAVQFHPEKSQNAGLTLLGNFVTWNPGEHASACDLSGASCA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)
Length
226 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
24.22 kDa
Sequence
MARTPNIALVDYGVGNLHSARKGLEAMGARVTLSGQPLTLSAADGVVLPGVGSFDTAITRLNDRGLGDAIIQLVRAGQPMLGICLGLQVLFDSSEEGRLPGLGLLPGRVRRFRSEPGLTIPHVGWNQLHFDNVDCPLWRDLAAGGWVYFVHSYYVDPARAEDRAASAVHGSQHFTAAVCRDNLMAVQFHPEKSADTGLRILKNFVERAASRSAAEVAARCATRPPA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)
Length
226 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
24.22 kDa
Sequence
MARTPNIALVDYGVGNLHSARKGLEAMGARVTLSGQPLTLSAADGVVLPGVGSFDTAITRLNDRGLGDAIIQLVRAGQPMLGICLGLQVLFDSSEEGRLPGLGLLPGRVRRFRSEPGLTIPHVGWNQLHFDNVDCPLWRDLAAGGWVYFVHSYYVDPARAEDRAASAVHGSQHFTAAVCRDNLMAVQFHPEKSADTGLRILKNFVERAASRSAAEVAARCATRPPA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
Length
225 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
24.434 kDa
Sequence
MTSAKNVIVDTGCANLSSVKFAVERLGFEVTITDDITIIQQAEKVIFPGVGSAKHAMKNIKAKNLEAALQGLTQPVLGFCLGMQLMTESSTEGKKSSTEGNNDDNTSHIVPCLNLIPTNVEPLKAQGNRLPHMGWNTLTQVSNHPIFKGISEGDYFYFVHSFAAPISEYTIASCEYGSTFSAAIAKDNFIGCQFHPERSSALGSKIIQNFLELDSTELNQELVNL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)
Length
225 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
24.457 kDa
Sequence
MSTIAIVDYGMGNFHSVARALQHAAPDADIRICNRPEQIDAADRVVFPGQGAMPDCMRTLNESGLRAAVERAAASKPLMGVCVGEQMLFERSEEGDTPCLGIFPGEVRRFAGPQFADPVAADQAAAAPPAAARERLKVPHMGWNQVRQTRSHALWEGIPDGTHFYFVHSYYAAPSDPALTTGVTDYGVAFTCAVAAANIFAVQFHPEKSAEHGLRLYRNFVDWQP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
Length
225 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
24.457 kDa
Sequence
MSTIAIVDYGMGNFHSVARALQHAAPDADIRICNRPEQIDAADRVVFPGQGAMPDCMRTLNESGLRAAVERAAASKPLMGVCVGEQMLFERSEEGDTPCLGIFPGEVRRFAGPQFADPVAADQAAAAPPAAARERLKVPHMGWNQVRQTRSHALWEGIPDGTHFYFVHSYYAAPSDPALTTGVTDYGVAFTCAVAAANIFAVQFHPEKSAEHGLRLYRNFVDWQP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)
Length
225 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
24.399 kDa
Sequence
MSTIAIVDYGMGNFHSVARALQHAAPDADIRICNRPEQIDAADRVVFPGQGAMPDCMRTLNESGLRAAVERAAASKPLMGVCVGEQMLFERSEEGGTPCLGIFPGEVRRFAGPQFADPVAADQAAAAPPAAARERLKVPHMGWNQVRQTRSHALWEGIPDGTHFYFVHSYYAAPSDPALTTGVTDYGVAFTCAVAAANIFAVQFHPEKSAEHGLRLYRNFVDWQP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Shewanella loihica (strain ATCC BAA-1088 / PV-4)
Length
224 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.971 kDa
Sequence
MSNPDTIIIDTGCANLSSVRYAFERIGADVEVSDDIDKIKAATRVVLPGVGTARAAMKALKDKKLIDTICSLTQPVLGVCLGMQMLTKASQERGGLSYGNSSKDCQCLGLIDTNIEQLDAKGLPLPHMGWNQISPSEHPLFAGVAEGSYVYFVHSYRAPLGDFTIAKCEYGEGFSAAIAKDNFMGVQFHPEKSAAVGATILRNFMKMNAGSFAGNHKSTQESAQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Shewanella oneidensis (strain MR-1)
Length
221 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.641 kDa
Sequence
MSANTDEFDVVIIDTGCANLSSVRFAFERLGANVLVTDDKASIKAAKRVVLPGVGSAGAAMASLTEKALVELIQGLTQPVLGVCLGMQMLTLLSKERGGQALDCQAHDCKCLGIIPTEIDELNSQTLKAEGLPLPHMGWNQLTFSNPSQVHPLFAGVEAGSYVYFVHSYRAPLSDYTLAQCRYGEDFSAAIGKDNFMGVQFHPEKSAAVGAQILGNFLKMQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length
219 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.812 kDa
Sequence
MKVVVIDSGTGNLASARRGLEIAAGRAGLDAKVIASADPLDVRNADRIVLPGQGAFADCARGIAAIEGMRGAIEEGVAAGKPFLGICVGMQLMAERGLEHEGAPGFGWIKGEIAPISCPGLRLPQMGWNGLDFTSTGCVHPLLNGLQADDHAYFVHGYALRDGDQAQILATTEYGGPVVAMVASGNRAGTQFHVEKSQEVGLRILQNFMVWTPEGTSGS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length
219 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.812 kDa
Sequence
MKVVVIDSGTGNLASARRGLEIAAGRAGLDAKVIASADPLDVRNADRIVLPGQGAFADCARGIAAIEGMRGAIEEGVAAGKPFLGICVGMQLMAERGLEHEGAPGFGWIKGEIAPISCPGLRLPQMGWNGLDFTSTGCVHPLLNGLQADDHAYFVHGYALRDGDQAQILATTEYGGPVVAMVASGNRAGTQFHVEKSQEVGLRILQNFMVWTPEGTSGS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Renibacterium salmoninarum (strain ATCC 33209 / DSM 20767 / JCM 11484 / NBRC 15589 / NCIMB 2235)
Length
219 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.467 kDa
Sequence
MMATVTVLDYGSGNVRSAVRALERAGAEVTLSAKADDVLNADGLVVPGVGAFATVMKELKSVDALRMIGRRVAGGRPVLAICVGLQILFEAGVEHGNSEPGMGEWPGTVELLPADVVPHMGWNTVQAPADSMLFDGVRDERFYFVHSYGVQHWDFDVTQPKMKPPAVTWSEHGAKFIAAVENGPLCATQFHPEKSDDAGARLLKNWVDSLPATGRNQVA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
Length
218 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.959 kDa
Sequence
MDTTGTGQRGASIVVVDYGLGNLRSVTRGLERASADVSIVGDPGALDDADGIVLPGVGAFGDGMENAGPFRDALTDAADEGRPLFGICLGMQMLLSSSEEADHEGQGDARGLDLIPGRNVRFTGTVKVPHMGWNELAVTRDHPLVGGVDGEYAYFVHSYYAAPDDPGHVVAETDYGERFPAVVANDAGNVFGTQFHPEKSGATGLRILRNFVDYCADQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
Length
218 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.959 kDa
Sequence
MDTTGTGQRGASIVVVDYGLGNLRSVTRGLERASADVSIVGDPGALDDADGIVLPGVGAFGDGMENAGPFRDALTDAADEGRPLFGICLGMQMLLSSSEEADHEGQGDARGLDLIPGRNVRFTGTVKVPHMGWNELAVTRDHPLVGGVDGEYAYFVHSYYAAPDDPGHVVAETDYGERFPAVVANDAGNVFGTQFHPEKSGATGLRILRNFVDYCADQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Salinibacter ruber (strain DSM 13855 / M31)
Length
218 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.661 kDa
Sequence
MTTIIDYGIGNLRSIEKAFETVGATVHRTDDPAAIAEAERLVLPGVGAFRACIDEIRRRDLEGPIHDAIGRGVPFLGVCVGMQLLFETGYEKGEHEGLGVLPGHVAHFRETDAGMPDELTVPHMGWNAIEPTRDHPLLDELGATPYVYFVHSYHPVAEDADDVLTTTSYGHTFPSVVQRDNVFGVQFHPEKSQAAGLGLLDNFAALPTTEEAGRTVST

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Shewanella sediminis (strain HAW-EB3)
Length
218 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.266 kDa
Sequence
MNQADNSTVIIDTGCANLSSVRYAFERICSDVIVSDNHDLIKAATRVVLPGVGTAGAAMASLKDKSLVGLIQGLTQPVLGVCLGMQMMTQVSKEHGGRDIDCECLGLIPTDVEELNSQGQPLPHMGWNQISPSMHPLFAGIPAGSYLYFVHSYRVPLSDYTIASCEYGETFSAAIAKDNFMGVQFHPEKSAAIGSKILSNFLALDKASLDAALQEPKS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949)
Length
217 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.457 kDa
Sequence
MLAILDYKAGNQTSVRRALEHLGVPCAITADPAMLESAAGVIFPGVGAAGQAMSALAEAGLDKALHHVARRGQPLLGICLGCQILLESSEENAAKTLGIVPGVCRRFEDHMRQEDGSAAPVPHMGWNSLEAVAPCVLLDGIDPASEYYFVHSYYVEPDPSLVLATTTYGRTFCSLYGRDGLWAAQFHPEKSGRPGLRLLGNFYEYCRQSRQEARHAQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Helicobacter hepaticus (strain ATCC 51449 / 3B1)
Length
217 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
24.227 kDa
Sequence
MSKLRVGIINYGVGNLGSVQNAFAFIQTHFSDVLPHTLEIKVESHPERLQDYDKLLLPGVGAFGNAMTHLKNTHLDEAIREFVQSGKFLIGICLGMQLLFEQSEEFGNHKGLGLIEGKVVGFEHIAPLKVPHIGWNSCNFTPEGKHSKLFRGIADGSFFYFVHSFHIQTQPQFILAQCTYGYPFGAIVHKDNLFAIQAHPEKSHNVGLRLLANFLTL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)
Length
217 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.194 kDa
Sequence
MASTPQIAVVDYDMGNLHSACKGLEAAGANPIVTADPATILAADGVLLPGVGAFDPAMDHLRDRQLIEPLHQAATSGKPFLGICLGLQLLFEASEEGQSAGLGILPGRVQRFRSEPGLVIPHMGWNQLQLQQPDCPLWQNLGADPWFYFVHTYYVVPSEPTLTAATVQHGSQPVTAAIARDRLWAVQFHPEKSAKAGLQLLANFVTQVAAAQLQTVA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Helicobacter hepaticus (strain ATCC 51449 / 3B1)
Length
217 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
24.227 kDa
Sequence
MSKLRVGIINYGVGNLGSVQNAFAFIQTHFSDVLPHTLEIKVESHPERLQDYDKLLLPGVGAFGNAMTHLKNTHLDEAIREFVQSGKFLIGICLGMQLLFEQSEEFGNHKGLGLIEGKVVGFEHIAPLKVPHIGWNSCNFTPEGKHSKLFRGIADGSFFYFVHSFHIQTQPQFILAQCTYGYPFGAIVHKDNLFAIQAHPEKSHNVGLRLLANFLTL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)
Length
217 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.194 kDa
Sequence
MASTPQIAVVDYDMGNLHSACKGLEAAGANPIVTADPATILAADGVLLPGVGAFDPAMDHLRDRQLIEPLHQAATSGKPFLGICLGLQLLFEASEEGQSAGLGILPGRVQRFRSEPGLVIPHMGWNQLQLQQPDCPLWQNLGADPWFYFVHTYYVVPSEPTLTAATVQHGSQPVTAAIARDRLWAVQFHPEKSAKAGLQLLANFVTQVAAAQLQTVA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Cupriavidus necator (strain JMP 134 / LMG 1197)
Length
217 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.661 kDa
Sequence
MTTIAIVDYGVGNLRSVAQALRAAAPEADVRVVDAPEGIRSADRVVLPGQGAMPDCMSALGASGLQEAVIEAAASKPMFGVCVGEQMLFESSSEARPGTDKTPCLGLMPGEVIRFELDGMTQPDGSRYKVPQMGWNRVKQSRPHPLWDGIPDESWFYFVHSYFVRAQDPAHIAGETEYGVVFTSAVARDNIFATQFHPEKSAAMGLQLYRNFVHWNP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Ralstonia solanacearum (strain GMI1000)
Length
217 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.85 kDa
Sequence
MTTIAIVDYGMGNLRSVAQALSTVAPDADVRISAQADEIRAADRVVLPGQGAMPDCMAAFDQSGLREAVLEAARTKPMLGVCVGEQMLLERSAEARAGEAFTAGLGLISGDVIRFDLDGRLQPDGSRYKVPQMGWNRVHQSRTHALWAGVPDQSYFYFVHSYYARPAHPDESVGETEYGVRFTCAIARDNIFATQFHPEKSAQAGLQIYRNFVHWKP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Length
217 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.496 kDa
Sequence
MSSVAVIDYGMGNLHSIAKALQHADANAAVTVTSDPDVILASDRVVFPGVGAMRDCMAHLAERRLEQVVRRAAAEKPFLGICLGMQALLEESEENGGTRCLGLITGRVLRFPEGLTGAAGEPLKIPHMGWNRVHFSDPSHPLWAGIPAESWFYFVHSYYAAPADPADVAATSDYPTPFAAAVARGKVFAVQFHPEKSQAAGLRLLANFLRWEPWSSR

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
Length
216 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.63 kDa
Sequence
MSVAIVDYGSGNLHSAAKAFERAARSMENPEPILVTRDPDQVFRADRVVLPGVGAFADCRKGLDSIDGMVQALNETVRDKARPFFGICVGMQLMATRGKEHVTTDGLNWIAGDVVKIAPDREDLKIPHMGWNTLDPVREHPVLEKLPLGPKGLHAYFVHSFHLAAEHEGDVLARADYGGPVTAVVGKDTAIGTQFHPEKSQRFGLALISNFLKWKP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Length
216 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.571 kDa
Sequence
MSIAIIDYGSGNLHSAAKAFERAARSLEDPQKVFVTSDPDQAYGADRLVLPGVGAFADCRRGLDAVNGMVEAITEAVRVKARPMFGICVGMQLFATRGKEHVITQGLNWIGGDVEKITPRDESLKIPHMGWNTLDVLREHPVLNKLPLGPKGQHAYFVHSYHLNAANEADVLARADYGGPVTAIVAKDTAIGTQFHPEKSQRFGLALISNFLRWKP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Brucella abortus (strain 2308)
Length
216 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.232 kDa
Sequence
MRVAIIDYGSGNLRSATKAFERAAHESGISAEIDLTCDAQRVASADRIVLPGVGAYADCRRGLDAAPGMVEALNDTVLKKARPFLGICVGMQLMSERGLEKTVTNGLGWIAGDVREMVPSDASLKIPQIGWNRIHVKHSHPIFDGIPTGDDGLHAYFVHSYMLDAKNASDVLAVTDYGGDVTAAVGRDNMVGTQFHPEKSQLLGLSLIANFLKWKP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Brucella abortus biovar 1 (strain 9-941)
Length
216 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.232 kDa
Sequence
MRVAIIDYGSGNLRSATKAFERAAHESGISAEIDLTCDAQRVASADRIVLPGVGAYADCRRGLDAAPGMVEALNDTVLKKARPFLGICVGMQLMSERGLEKTVTNGLGWIAGDVREMVPSDASLKIPQIGWNRIHVKHSHPIFDGIPTGDDGLHAYFVHSYMLDAKNASDVLAVTDYGGDVTAAVGRDNMVGTQFHPEKSQLLGLSLIANFLKWKP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)
Length
216 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.294 kDa
Sequence
MRVAIIDYGSGNLRSATKAFERAAHESGISAEIDLTCDAQRVASADRIVLPGVGAYADCRRGLDAVPGMVEALNDTVLKKARPFLGICVGMQLMSERGLEKTVTNGLGWIAGDVREMVPSDASLKIPQIGWNRIHVKHSHPIFDGIPTGDDGLHAYFVHSYMLDAKNASDVLAVTDYGGDVTAAVGRDNMVGTQFHPEKSQLLGLSFIANFLKWKP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Brucella suis biovar 1 (strain 1330)
Length
216 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.23 kDa
Sequence
MRVAIIDYGSGNLRSATKAFERAAHESGISAEIDLTCDAQRVASADRIVLPGVGAYADCRRGLDAVPGMVEALNDTVLKKARPFLGICVGMQLMSERGLEKTVTNGLGWIAGDVREMVPSDASLKIPQIGWNRIHVKHSHPIFDGIPAGDDGLHAYFVHSYMLDAKNASDVLAVTDYGGDVTAAVGRDNMVGTQFHPEKSQLLGLSLIANFLKWKP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)
Length
216 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.331 kDa
Sequence
MRVAIIDYGSGNLRSATKAFERAAREGGISAEIDLTADADRVRTADRIVLPGVGAYADCAAGLRAVDGMWEAVEDVAIAQSRPFLGICVGMQLMSERGLEKTVTHGFGWISGDVKEITPTDPALKIPQIGWNTIELRRQHPLFAGIPTGPEGLHAYFVHSYHLDAKKPDEILAVADYGGPVTAAVARDNLVGTQFHPEKSQALGLALITNFLRWRP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Rhizobium meliloti (strain 1021)
Length
216 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.281 kDa
Sequence
MRVAIIDYGSGNLRSATKAFERAAREAGIAAEIDLTDRPERVATADRIVLPGVGAYADCRRGLAVVEGMEEALTEAVEKTGRPFFGICVGMQLMSSRGLEKTVTKGFGWIAGDVVGMTPEDPSLKIPQIGWNTLDLKRPHPLFDGIPTGENGLHAYFVHSYHLAAERAEDVVAEAGYGGPVTAFVARDNKAGSQFHPEKSQALGLALISNFLRWKP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Agrobacterium fabrum (strain C58 / ATCC 33970)
Length
216 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.138 kDa
Sequence
MRVAIIDYGSGNLRSATKAFERAAREAGIDATIDLTDKPDHVASADRIVLPGVGAYADCSAGLNAMPGMHEALIEAVEKKAHPFLGICVGMQLMSSRGLEKTVSTGLGWIEGDVVEMTPSDPTLKIPQIGWNTLEIRHAHPLFDGIKTGADGLHAYFVHSYHLAAKHSTDVIATTNYGGAMTAFVGRDNMAGAQFHPEKSQTLGLALISNFLRWKP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
Length
215 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.611 kDa
Sequence
MSTTPVRAAPEVLLLDYGAGNVRSAARALERAGMTVRVTDNAADVPHAPALVVPGQGHFRQVMEAFEHGGFHGPVLDAARAGVPLLGICVGMQLLFDGSEEAPGVPGLGLIAGQVRKFAPAPERKVPQMGWNALEARGDSPLLRGLGPDAYAYFVHSYYVPVDVPVTDGAVTDYGVPFWSALSRGNLHAAQFHPEKSGAVGLALLANFRRELAPA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit hisH
Organism
Cyanophora paradoxa
Length
215 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
23.795 kDa
Sequence
MINSKNNSPIEISIIDYQMGNLYSVCKGIERSGGIPKIINSAEEIKKATALILPGVGSFDPAMKQLKKQDLINPIKDAISEKKPFLGICLGLHLLFEESEEGIESGLGILSGSVKRIKNEPEITIPHMGWNQLQLTNPKCYLWDGLTKYPWVYFVHSYFAQPKNPNVIAAAVTHGTQQVTAAIQYENISAVQFHPEKSASIGLHMLNNFVQQSCN

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Dechloromonas aromatica (strain RCB)
Length
215 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.42 kDa
Sequence
MTLAGQTIAVIDYGMGNLRSVSKALEHVAGGKQVIVTADPAVVAAAERVVFPGQGAMPDCMRELDARGLRTAVLAAAKDKPFLGICVGEQMLFEHSDEGNVPALGVFAGNVKRFPDEKMHLPTGERLKVPHMGWNEVRQKPHALWSGIADGSRFYFVHSYFVEPADLALVTGICEYGVPFTCAVGRDNIFAVQFHPEKSARDGLQLLKNFVEWQP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bifidobacterium longum (strain NCC 2705)
Length
215 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.225 kDa
Sequence
MTTAVVFDYGFGNVRSMVRALANLGVDTTLTSDYRQSLEADGLVVPGVGAFAACMEGLKKVDGDRVIYDRIRAGRPVLGVCVGEQIMFEHGLEHGAHAAGIGLIGGSVNLLDADVVPHMGWDTIETAPDSVLLNGVENERFYFVHSYAAMEVKPADTSRFDIDLSDSPERVSWCSYGRSRFVAAYEHGPLSATQFHPEKSGDAGSQLLKNWIATL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara)
Length
215 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.978 kDa
Sequence
MDTTDRTAEVVLVDYGLGNLRSVTRGLERAGAEVTLSADPDDFSAADGIVLPGVGAFSEGMENAGPFREALVAAAADGQPLFGICLGMQMLLTSSEEAETVGQGDVRGLDLVPGRNVRFDEGQKVPHMGWNELNVARDHPIVEGIDGEYAYFVHSYYAAPDDDAAVVATTDYSVEFPAIVANEAGNVFGTQFHPEKSGETGLQILQNFVDYCLER

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Trichodesmium erythraeum (strain IMS101)
Length
214 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.098 kDa
Sequence
MSTIAVIDYDMGNLHSVCKGLEKAGATPKITDSSIEIDKADAVILPGVGSFDPAVQHLRTRNLEIPIKQVIASGKPFLGICLGLQILFESSEEGQEPGLGIFAGKVCRFKSEPGLTIPQMGWNKLQFTQPEHLLWSEIGSQPWVYFVHSYYVDPTDSQVTAATVTHGHQTVTAAVGKDNLIAVQFHPEKSSTAGLKILSNFVSKVIPKNLALAS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Trichodesmium erythraeum (strain IMS101)
Length
214 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.098 kDa
Sequence
MSTIAVIDYDMGNLHSVCKGLEKAGATPKITDSSIEIDKADAVILPGVGSFDPAVQHLRTRNLEIPIKQVIASGKPFLGICLGLQILFESSEEGQEPGLGIFAGKVCRFKSEPGLTIPQMGWNKLQFTQPEHLLWSEIGSQPWVYFVHSYYVDPTDSQVTAATVTHGHQTVTAAVGKDNLIAVQFHPEKSSTAGLKILSNFVSKVIPKNLALAS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit hisH
Organism
Cyanidium caldarium
Length
214 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
24.305 kDa
Sequence
MKNIGIINCGMGNLHSVSNAISNIGFNPVIINASKDLVSFACSALVLPGVGSFDLAIDRLEKKNLIEPVKLWIQEDRPFVGICLGLQLLFEGSDEGSKPGLKIFNGYVSQFKHSLVKKVPHMGWNKLYFNRFNTIDNLVPHYFHYDLQPWAYFVHSYYIEPKDCYTFNTTSLTFYGKQKIVSSISYNNILATQFHPEKSGLFGLFILKRFLSSY

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125)
Length
214 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
23.603 kDa
Sequence
MLGIIDYGMGNLHSVSKALERLSWSYIVSEQPEELQKADGLILPGVGSFHDAMSILNETGLTAFIKDWVDEGKPLLGICLGMQLLFEESEENKRTKGLSLLPGRVIRFPGVATDGSTYKVPHMGWNQLTFRKPNHPLLTDVEEGHVYFVHSYVVKTDADDVLLATSHYYETVPAVVGRGNILGTQFHPEKSSNVGMSILRNYGAMVEKGVKARG

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIB 8255 / S1)
Length
214 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.686 kDa
Sequence
MRVALIDYGSGNLRSAAKALERAARDGGVAAEIVVTRDVEGVLGADRVVLPGVGAFANCRRGLQGIDGMVEALAEVALVRARPFLGICVGMQLLADEGVEYGRHPGLGWIGGTVEAISPADPALKIPHMGWNSLDFQADSHALLAGIEPGTHVYFVHSYHFRPADPATRLASVEYGGPLTAMIGRENLVGTQFHPEKSQAAGLRLIANFLRWAP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Psychrobacter arcticus (strain DSM 17307 / 273-4)
Length
214 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.326 kDa
Sequence
MSRATKIALLDYGMGNLHSASKALSAVGAEVSITNDPKVVAAADKIFFPGVGAMRDCIAGMHEAGIDDVIRQAIFNKPVMAICVGMQALFEQSAENGGTPCLSILDGTVPAFNPEWKDEKGVQIKVPHMGWNTISGMNFEHPLWNGIEDKAHFYFVHSYYCEPADSSQVAAICDYGQPFCASILQDNLFATQFHPEKSHTAGLQLLKNFVDWDI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Acaryochloris marina (strain MBIC 11017)
Length
214 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.195 kDa
Sequence
MPIIAVIDYDMGNLHSACKGLQEAGTQTIVSDRPEDLVSADAVVLPGVGAFDPAMQHLRSRQLIPVIQDILASGKPFLGICLGLQILFEGSEEGTEAGLGIIPGTVKRFQSEPGITIPHMGWNQLEYQQPDLPLWRHSPAQPWVYFVHSYYVDPVDPTVKAATVTHGTQTITAAIARDNLMAVQFHPEKSSTFGLQILANFVEQVQATLATPAV

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Desulfovibrio alaskensis (strain G20)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.977 kDa
Sequence
MLAILKYKAGNQTSVRRALNHIGIPNVITADPAEIAASEGIIFPGVGAAGQAMDELTAAGLDAVLKEQVEAGKPLLGICVGCQIMLDYSQENDTRTLGIIPGECHLFNPALEDETGAPIRVPHMGWNRVIPRKPCALFKGISDDAEFYFVHSYFPNPQPDYVIATTTYGKEFCSVHGGPGLWAVQFHPEKSGRPGLKLLSNFHAYCKEAANAQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.259 kDa
Sequence
MLAILDYKAGNQTSVRRALDHLGIPCVITADPEVIQGAAGVIFPGVGAAGQAMNELVTTGLDEVLRRQVQAGRPLLGICVGCQIMLDYSQENDTKALGIIPGECRLFNPAWTDEDGAPIRVPHMGWNHIVQRRPCELLKGIEPEAEFYFVHSYYPAPPEEYVIATCTYGAEFCAIHGGPGLWAVQFHPEKSGRPGLRLLANFHRYCTEAADAQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.308 kDa
Sequence
MLAILDYKAGNQTSVRRALDHLGIPCVITADPEVIQGAAGVIFPGVGAAGQAMNELVTTGLDEVLRRQVQAGRPLLGICVGCQIMLDYSQENDTKALGIIPGECRLFNPAWTDEDGAPIRVPHMGWNRIVQRRPCELLKGIEPEAEFYFVHSYYPAPPEEYVIATCTYGTEFCAIHGGPGLWAVQFHPEKSGRPGLRLLANFHRYCTEAADAQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Geobacillus thermodenitrificans (strain NG80-2)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.302 kDa
Sequence
MTMIGVIDYGMGNLYSVSKALERLGCPYIVSGDKEELARVRGLILPGVGSFRDAMHILRETGLADFIRSAVQDGTPLLGICLGMQLLFDESEENGPTEGLGLLRGRVVRFPGVTNDGEPYKVPHMGWNRLRFHRSSPLLDGVEEGHVYFVHSYYVVPGEEEVVLASSEYDVDVPAVVGRDNVFGTQFHPEKSGAVGMSILNRYVGIVTGRENG

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Hydrogenovibrio crunogenus (strain XCL-2)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.666 kDa
Sequence
MTDQKLVTVIDYGMGNLRSVAKAAEHAADSNTRICISDKAEDIRSADAIIFPGQGAAKACMKALNETNITHALIQAATEKPFLGICMGLQVLMTHSQENEGVDCLDILKGDVQKFDLSGHPELKMPHMGWNQIHQTIDHPLWHNIEQNSRFYFVHSYFVSPHDKQIIAGETTHGKRFTSAIAQNNLFAIQAHPEKSADAGLQLFKNFLNWNGQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Legionella pneumophila
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
23.31 kDa
Sequence
MSSVSIVDYGVGNLLSVARAFQYFDASVNLVSTPEEIMSADRLVLPGVGAFEDGMKGLTTLNFIEPIKQFARSGKPFLGICLGMQMMLSRSTEFGQHEGLDLIAGEVVSVPSHGVDGQLHKIPHIGWNELVSTSEGEDWCHTILKNIPLNSSVYFVHSFMAMPSNPKKRLADTLYDGQAISAVIKDENMYGCQFHPEKSGEVGLSIIQQFLQI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Synechococcus sp. (strain CC9902)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.021 kDa
Sequence
MGLNLGVIDYGMGNLHSVGKALERLGEQAVLVQGPEDLKSVDALILPGVGSFDPAIENLRATGLIPHLKDWGNNNRPLLGICLGLQLLFERSDEGSKDGLGLFQGAVERLQSHPNERIPHMGWAPLTVERNCPLLHSDDPTPWVYFVHSYAAVPLNSSVLAATAAYGNAAVTAMVWSGRIGACQFHPEKSSAAGEAMLKRWLHWLHQGAEPVH

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Synechococcus sp. (strain CC9605)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.167 kDa
Sequence
MSLNLGLIDYGMGNLHSVEKCLERLDQGCSLINNSDDLEGIDALILPGVGAFDPAMANLRATGLVPHLLRWGQEDRPLLGICLGLQLLFEQSDEGSDPGLGLLGGRVTRLPSKSGERIPHMGWAPLKHHGTCPLLSSDASSEWVYFVHSYAAVPTDRNDLKASAPFGDQEVTAVVWRGRVGACQFHPEKSSDAGEQMLKRWLTWLRNGAEPCP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Geobacillus thermodenitrificans (strain NG80-2)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.302 kDa
Sequence
MTMIGVIDYGMGNLYSVSKALERLGCPYIVSGDKEELARVRGLILPGVGSFRDAMHILRETGLADFIRSAVQDGTPLLGICLGMQLLFDESEENGPTEGLGLLRGRVVRFPGVTNDGEPYKVPHMGWNRLRFHRSSPLLDGVEEGHVYFVHSYYVVPGEEEVVLASSEYDVDVPAVVGRDNVFGTQFHPEKSGAVGMSILNRYVGIVTGRENG

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Hydrogenovibrio crunogenus (strain XCL-2)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.666 kDa
Sequence
MTDQKLVTVIDYGMGNLRSVAKAAEHAADSNTRICISDKAEDIRSADAIIFPGQGAAKACMKALNETNITHALIQAATEKPFLGICMGLQVLMTHSQENEGVDCLDILKGDVQKFDLSGHPELKMPHMGWNQIHQTIDHPLWHNIEQNSRFYFVHSYFVSPHDKQIIAGETTHGKRFTSAIAQNNLFAIQAHPEKSADAGLQLFKNFLNWNGQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Legionella pneumophila
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
23.31 kDa
Sequence
MSSVSIVDYGVGNLLSVARAFQYFDASVNLVSTPEEIMSADRLVLPGVGAFEDGMKGLTTLNFIEPIKQFARSGKPFLGICLGMQMMLSRSTEFGQHEGLDLIAGEVVSVPSHGVDGQLHKIPHIGWNELVSTSEGEDWCHTILKNIPLNSSVYFVHSFMAMPSNPKKRLADTLYDGQAISAVIKDENMYGCQFHPEKSGEVGLSIIQQFLQI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Synechococcus sp. (strain CC9902)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.021 kDa
Sequence
MGLNLGVIDYGMGNLHSVGKALERLGEQAVLVQGPEDLKSVDALILPGVGSFDPAIENLRATGLIPHLKDWGNNNRPLLGICLGLQLLFERSDEGSKDGLGLFQGAVERLQSHPNERIPHMGWAPLTVERNCPLLHSDDPTPWVYFVHSYAAVPLNSSVLAATAAYGNAAVTAMVWSGRIGACQFHPEKSSAAGEAMLKRWLHWLHQGAEPVH

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Synechococcus sp. (strain CC9605)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.167 kDa
Sequence
MSLNLGLIDYGMGNLHSVEKCLERLDQGCSLINNSDDLEGIDALILPGVGAFDPAMANLRATGLVPHLLRWGQEDRPLLGICLGLQLLFEQSDEGSDPGLGLLGGRVTRLPSKSGERIPHMGWAPLKHHGTCPLLSSDASSEWVYFVHSYAAVPTDRNDLKASAPFGDQEVTAVVWRGRVGACQFHPEKSSDAGEQMLKRWLTWLRNGAEPCP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.882 kDa
Sequence
MKNQASSTVALIDYGAGNLRSVANALLASGLARENLVVTANPDEVLQADRVVLPGVGAFASCMQALKAIPDMVPALEKAVLEKGRPFLGICVGMQLLADQGEEYGVHQGLGWIKGKVTPLRPNDPSCKVPHMGWNQIGLTTDSHPLLRAGEAYFLHSYAFVPEDESTLLATTEHGGLVTAAVGRDNIMGVQFHPEKSQSYGLEFLSRFLDWNP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.35 kDa
Sequence
MKTSIAIVDYGMGNLRSVAQALKKAEPAADVAIVDTPAAIRAADRVVLPGQGAMPDCMRSLGESGLQEAVIEASRTKPLLGVCVGEQMLFDWSAEGDTKGLGLLPGKVVRFELDGRLQDDGSRFKVPQMGWNRVRQSQPHPLWDGVPDDAYFYFVHSYYVTPDNPAHTVGETAYGAPFTSAVARDNLFATQFHPEKSAEVGLRLYRNFVHWKP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Burkholderia multivorans (strain ATCC 17616 / 249)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.359 kDa
Sequence
MKTSIAIVDYGMGNLRSVAQALKKAEPAADVAIVDTPAAIRAADRVVLPGQGAMPDCMRCLGESGLQEAVVEASRTKPLLGVCVGEQMLFDWSAEGDTKGLGLLPGKVVRFELDGRLQDDGSRFKVPQMGWNRVRQSRAHALWDGVPDDAYFYFVHSYYVMPDDPAHTVGETAYGAPFTSAVARDNIFATQFHPEKSAEVGLRLYRNFVHWKP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Burkholderia mallei (strain ATCC 23344)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.513 kDa
Sequence
MKTSIAIVDYGMGNLRSVAQALMKAEPAADVKIVDRPEAIRAADRVVLPGQGAMPDCMRCLGESGLQEAVVEASRTKPLLGVCVGEQMLFDWSAEGDTKGLGLLPGKVVRFALEGRLQDDGSRFKVPQMGWNRVRQTQAHPLWDGVPDDAYFYFVHSYYVVPDNPAHTAGETLYGDVFTSAVARDNLFATQFHPEKSAEVGLRLYRNFVHWNP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Burkholderia pseudomallei (strain 1710b)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.513 kDa
Sequence
MKTSIAIVDYGMGNLRSVAQALMKAEPAADVKIVDRPEAIRAADRVVLPGQGAMPDCMRCLGESGLQEAVVEASRTKPLLGVCVGEQMLFDWSAEGDTKGLGLLPGKVVRFALEGRLQDDGSRFKVPQMGWNRVRQTQAHPLWDGVPDDAYFYFVHSYYVVPDNPAHTAGETLYGDVFTSAVARDNLFATQFHPEKSAEVGLRLYRNFVHWNP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Burkholderia pseudomallei (strain K96243)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.513 kDa
Sequence
MKTSIAIVDYGMGNLRSVAQALMKAEPAADVKIVDRPEAIRAADRVVLPGQGAMPDCMRCLGESGLQEAVVEASRTKPLLGVCVGEQMLFDWSAEGDTKGLGLLPGKVVRFALEGRLQDDGSRFKVPQMGWNRVRQTQAHPLWDGVPDDAYFYFVHSYYVVPDNPAHTAGETLYGDVFTSAVARDNLFATQFHPEKSAEVGLRLYRNFVHWNP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Caulobacter vibrioides (strain ATCC 19089 / CB15)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.581 kDa
Sequence
MQTVALIDYGSGNLRSAEKALREAARRRALDADIVVTADPDLVAKADRVFLPGVGAFASCRAGLDATGVYEAMNQAVHGRGVPFMGICVGHQLLATEGLEFGVTPGLNWIQGQVKKLEPNDPTLTIPHMGWNAISLVRPHALFAGIDDGAHMYFANSFALTPSHVEDVVATADHGGPFTAAVAKDNVAGVQFHPEKSQASGLALLANFLEWRP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)
Length
213 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.795 kDa
Sequence
MILNIGLIDYGMGNLHSVEQSFKRLNQSLKIISGPNDLSNCDALILPGVGSFDPAMKNLQQTNLIPELKKWVLNNKPLLGICLGLQLLFESSDEGKSKGLGLLKGTIKHLPKSEKQLIPHMGWAELNQDKECPLFKSNSSPQWMYFVHSYSAIPSDKNDIASSVNFGDEKITAVVWKKKLAACQFHPEKSGRSGELLLSNWLAWLKKETKDLY

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Desulfovibrio salexigens (strain ATCC 14822 / DSM 2638 / NCIB 8403 / VKM B-1763)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.713 kDa
Sequence
MLAILDYKAGNQTSVQRALNKLGIPNQITSDKEVLSKATGIIFPGVGAAGQAMDELTSGGLDELLKDLVQQKKPLLGICVGCQILLDYSEENDTQALSVIPGECRLFNPSWEDYEGVPIRVPHMGWNQIELKQDCILFKDIDPEAHFYFVHSYYPAPEEKYIIGETIYGRPFCSLHGREGLWAVQFHPEKSGRPGLKLLSNFYEYCKEVSDA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.964 kDa
Sequence
MLAILDYKAGNQTSVRRALDHLGIPCVITADPAVIAGAHGVIFPGVGAAGQAMNELLTTGLDKVLKDQVQAGKPLLGICVGCQIMLDYSQENDTKALGIVPGECRLFNAAWTEEDGTPIRVPHMGWNSIVQKRPCELLKGIEPEAEFYFVHSYYPAPPESYVIATCTYGEEFCAIHGGPGLWAVQFHPEKSGRPGLALLRNFYAYCKEASRA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Gluconobacter oxydans (strain 621H)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.578 kDa
Sequence
MRVVVIDYNGGNLASAAQAARKAATRKGIEADVVISRDATDILNADRLILPGQGAFADCAQGLGPALRNMLETATANGTPFLGICVGMQLMCEYGLEHGRTEGLGWISGNIRRMDEAANASLRLPHMGWNTLDFTPGAHLLTDGLIPGNHGYFVHSYALHDGADSDLVATAQYGTQVPAIVARGNRCGTQFHVEKSQDVGLTILGNFLRWTS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Gluconobacter oxydans (strain 621H)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.578 kDa
Sequence
MRVVVIDYNGGNLASAAQAARKAATRKGIEADVVISRDATDILNADRLILPGQGAFADCAQGLGPALRNMLETATANGTPFLGICVGMQLMCEYGLEHGRTEGLGWISGNIRRMDEAANASLRLPHMGWNTLDFTPGAHLLTDGLIPGNHGYFVHSYALHDGADSDLVATAQYGTQVPAIVARGNRCGTQFHVEKSQDVGLTILGNFLRWTS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.775 kDa
Sequence
MIAVINYGAGNLPNVVRALQRVGATLTVTDNPEVIRSAQAVVLPGVGATADTMASLRHLGIAEVLPAVIAASTPFLGICVGMQVLLSESEEFGLHSCLDIIPGTVRRLPEHAGKIPQIGWNQLQISPTFRNHPLFADIPDGADVYFVHSYYCAVADEAIIAARTDYGIPFPSVIIRDHLAAVQFHPEKSGDYGLRLLANFVRWSEAVQPKGV

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.359 kDa
Sequence
MKVAVIDYGMGNLHSVLKSLQAVNENGADIFLTRDPEAVVKADKVVFPGQGAMPDCMRELNRHGLAEAVRETTQSKPFFGICVGAQLLFEHSEEGDTAGLGLFPGKVVRFADDQVAGGERLKVPHMGWNQVYQTRSHPLFAGIADGERFYFVHSYHFAPADAALTLAESDYPQRFACIVGRGNIFATQFHTEKSHRAGLQMMKNFLAWDGNV

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / NBRC 12200 / NCIMB 9375 / NRRL NRS-1264 / Gibson 46)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.308 kDa
Sequence
MIGVIDYGMGNLYSVSKALERIDAPYFVSEHPDELKRADSYILPGVGAFRDAMEILTENGLKTFIQAAANEGKPLLGICLGMQLLFEESEEHGASEGLGLLKGKVVKLKDCDQAGNRLKVPHMGWNLLKVHRDSPLLPKAKEGFAYFVHSYYVSGIEEEALLASAEYGVCVPAVVGLGNVYGAQFHPEKSSTVGMLILERFKQFTQEQKVKK

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus pumilus (strain SAFR-032)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.397 kDa
Sequence
MIGVIDYGMGNLFSVSKALERAGARYIVSADVEELKKADAYILPGVGSFRDAMQLLKQTGLEGFIYQVVQEGKLLFGICLGMQLLFEESEEAGRTKGLGLLKGRVVLLKDHDKDGQKLKVPHMGWNELTFHQPSPLFDGVPEGFAYFVHSYYVRDMNPEEQLASADYGVQVPAIVGKGNVLGAQFHPEKSSTTGMALLKQFIQLANEQRVNK

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus subtilis (strain 168)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
23.303 kDa
Sequence
MIGVIDYGMGNLYSVSKALERVGVPYFVSEKPEELKEADAFILPGVGSFGDAMDNLGYTKLDQLIHDMVSEGRLLLGICLGMQLLFEESEENGTASGLGLLKGKAVRLKAEDEKGNKLKVPHMGWNRLSFHNESPLLTKTEQGYAYFVHSYYIDGMEENALLASADYGVRVPAVVGKRNVFGAQFHPEKSSTVGMSILTQFTKMAAEQKVKK

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / FZB42)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.259 kDa
Sequence
MIGVIDYGMGNLFSVSKALERVGVPYVVSDRPEELEKADAFILPGVGSFSDAMDNLRRAKLDQFIHRMVDEGKLLLGICLGMQLIFEESTENGSAKGLGLLAGKAVRLKDRDAEGNKLKVPHMGWNRLTFHQTSPLLSEAEEGFVYFVHSYYIDGMEDGDLLASAEYGVRVPAVVGKRNVFGAQFHPEKSGTAGMAILTQFTKMAAEQQVKK

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
23.207 kDa
Sequence
MLTVLVDYDSGNLHSAEKAFQRMATETGAGQVLVSDRPEDVARADRIVLPGDGAFPACRRALGSYGGLSEAIEEAVTRRARPFLGICIGMQMMATRGLEHEETPGFGWIAGEVVRIAPSDPHLKVPHMGWNDLTVDHPHPVLTGIETGDHAYFVHSYHFQVAHDAERLAHADYGADITAIVGRDTMVGTQFHPEKSQKTGLRLIANFLTWKP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.923 kDa
Sequence
MLTAIIDYESGNLHSAEKAFQRMARETGAGEVVVTSDADLVARADRLVLPGDGAFPACAAELRGHKGLYDAMVEAVEQKGRPFLGICVGMQLMATTGHEYEETPGLGWVAGDVVRITPENAALKVPHMGWNDLVIEAAHPIFDGIAGGDHVYFVHSYHFRVTNPTERLAHVDYGGPVTAVVGRDTMVGLQFHPEKSQAIGLRMIGNFLTWTP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.775 kDa
Sequence
MIAVINYGAGNLPNVVRALQRVGATLTVTDNPEVIRSAQAVVLPGVGATADTMASLRHLGIAEVLPAVIAASTPFLGICVGMQVLLSESEEFGLHSCLDIIPGTVRRLPEHAGKIPQIGWNQLQISPTFRNHPLFADIPDGADVYFVHSYYCAVADEAIIAARTDYGIPFPSVIIRDHLAAVQFHPEKSGDYGLRLLANFVRWSEAVQPKGV

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Prochlorococcus marinus (strain MIT 9211)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.676 kDa
Sequence
MNTNIGIIDYGMGNLHSVQQSFKRLDQSIRIVKSPNDVHECNALILPGVGSFDPAMENLRRTDLIPKIKSWVKDGKPLLGICLGLQLIFESSEEGNSEGLGLLKGKVCNLPRNTKERIPHMGWSLLKQIKECPLLDNENTSRWMYFVHSYSAIPSPEDLAATVSFGDSEVTAIVWKDSLGACQFHPEKSGKSGQRLLSSWLKWLHEKNSDLS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.572 kDa
Sequence
MQTVAVIDYGMGNLHSVAKALEHVGAGRVLITSDAKVIREADRVVFPGVGAIRDCMAEIRRLGFDSLVREVSQDRPFLGICVGMQALLDRSEESGGVDCIGLFPGQVKFFGKDLYEEGEHLKVPHMGWNQVAQAVDHPLWHDIPDLARFYFVHSFYIDAANQRQVVGRGHYGLDFAAALADGSRFAVQFHPEKSHTHGLQLLQNFAAWDGRW

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.367 kDa
Sequence
MQTVAVIDYGMGNLHSVAKALEHVGAGKVLITSDASVIREADRVVFPGVGAIRDCMAEIRRLGFDALVREVSQDRPFLGICVGMQALLDHSEENEGVDCIGLFPGQVKFFGKGLIEDGEHLKVPHMGWNEVKQAVDHPLWHNIADLARFYFVHSYYINAGNTRQVVGSGHYGVDFAAALADGSRFAVQFHPEKSHTHGLQLLQNFAAWDGRW

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Pseudomonas fluorescens (strain Pf0-1)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.32 kDa
Sequence
MQTVAVIDYGMGNLHSVAKALEHVGAGKVLITSDAAVIREADRVVFPGVGAIRDCMAEIRRLGFDSLVREVSQDRPFLGICVGMQALLDSSEENDGVDCIGLFPGAVKFFGKDLHEDGEHLKVPHMGWNEVKQAVDHPLWHNIPDLARFYFVHSYYIAAGNPRQVVGSGHYGVDFAAALAEGSRFAVQFHPEKSHTHGLQLLQNFAAWDGRW

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.535 kDa
Sequence
MQTVAVIDYGMGNLHSVAKALEHVGAGKVLVTSDASVIREADRVVFPGVGAIRDCMAEIRRLGFDSLVREVSQDRPFLGICVGMQALLEHSEENAGVDCIGLFPGQVRFFGKDLQEEGEHLKVPHMGWNEVSQTIDHPLWHDIPDRARFYFVHSYYINAGKPGQVVGRGHYGVDFAAALADGSRFAVQFHPEKSHTHGLQLLQNFIAWDGRW

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.575 kDa
Sequence
MQTVAVIDYGMGNLHSVAKALEHVGAGRVLITSDAKVIREADRVVFPGVGAIRDCMAEIRRLGFDSLVREVSQDRPFLGICVGMQALLDRSEESGGVDCIGLFPGQVKFFGKNLHEEGEHLKVPHMGWNQVTQAVDHPLWHDIPDLARFYFVHSFYIDAANQRQVVGRGHYGLDFAAALADGSRFAVQFHPEKSHTHGLQLLQNFAAWDGRW

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Pseudomonas syringae pv. syringae (strain B728a)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.523 kDa
Sequence
MQTVAVIDYGMGNLHSVAKALEHVGAGRVLITSDAKVIREADRIVFPGVGAIRDCMAEIRRLGFDSLVQEVSQDRPFLGICVGMQALLDSSEENGGVDCIGMFPGQVKFFGKDLHEEGEHLKVPHMGWNQVAQAVDHPLWHDIPDQARFYFVHSFYIDAANQRQVVGRGHYGLDFAAALADGSRFAVQFHPEKSHTHGLQLLQNFAAWDGRW

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.57 kDa
Sequence
MQTAIIDYGMGNLHSVLKSVRTAGQLAGKNTKIFLSGDPDRVSRADKVIFPGQGAMPDCMAALTRGGLDEAVKDALKNKPFFGICVGAQLLFDHSEEGNTDGLGWFGGKVRRFARDLRDPQGCRLKVPHMGWNTVRQTQNHPLFQGIPQNTRFYFVHSYYFAPENPETILGESDYPSPFACIVGKDNVFATQFHTEKSHDAGLTMLKNFLNW

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
23.599 kDa
Sequence
MQTAIIDYGMGNLHSVLKSVRTAGQLAGKNVEIFLSGDPERVSRADKVIFPGQGAMPDCMAALTRGGLDEAVKDALKNKPFFGICVGAQLLFDHSEEGNTDGLGWFGGKVRRFERDLLDPQGCRLKVPHMGWNTVRQTQNHPLFQGIPQDTRFYFVHSYYFAPENPETILGESDYPSPFACIVGKDNVFATQFHTEKSHDAGLTMLKNFLNW

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Neisseria meningitidis serogroup B (strain MC58)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
23.773 kDa
Sequence
MQTAIIDYGMGNLHSVLKSVRTAGQLAGKNTEIFLSGDPDRVSRADKVIFPGQGAMPDCMAALKRDGLDEAVKDALKNKPFFGICVGAQLLFDHSEEGNTDGLGWFGGKVRRFERDLRDPQGCRLKVPHMGWNTVRQTQNHPLFKDIPQDTRFYFVHSYYFAPENPETILGESDYPSPFACIVGKDNVFATQFHTEKSHDAGLTMLKNFLNW

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.34 kDa
Sequence
MNSIAVVDYGMGNLRSVSKALEYVDSSAVVTVTSDPETIRSAARVVVPGQGAMPHCMQALDDQGLRESVIEAAKNKPFLGICLGLQMLFEESEEGNIRALGILPGRVKKLESTDTADSDIPKIKIPHMGWNQVHQTLEHPLWHGIDTDTRFYFVHSYYVATDEPQIVAGSTEYPVPFTCAVARDNIFAIQFHPEKSHSAGLALLSNFLKWTP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.171 kDa
Sequence
MTDIAIVDYGMGNLRSVAKALEHVAPEAVIAVTNNPEVVRKAERVVVPGQGAMPDCLRELDRLGLREAVRDAAANKPFLGICIGLQMLFDSSEEGNVSGLGIVPGRVKRFPASAMKDEKGQKLKVPHMGWNQVHQSVGHSLWKNIANDSRFYFVHSYYVEPADADSAGHSAYPFSFTCAVAKDNIFAVQFHPEKSHAAGLTLLGNFVRWKPV

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Microcystis aeruginosa (strain NIES-843)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.011 kDa
Sequence
MTLIAVIDYDMGNLHSACKGLETVGAVPKITDSPLDLEKADAIVLPGVGSFDPAVRQIRSRHLEKPIKAAIANGKPFLGICLGLQILFETSEEGQEAGLGIIPGTVRRFRSEPGITIPHMGWNQLDFTQPDHALWQGLPPHPHVYFVHSYYVDPLDSHLTAATVTHGSQTVTAAIARDRLVAVQFHPEKSSTNGLKILANFVQQVQKLALVS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Aromatoleum aromaticum (strain EbN1)
Length
212 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.82 kDa
Sequence
MSDVAIIDYGMGNLRSVAKAIEHVAPGKRVAVTSDPAVVAAAARVVFPGQGAMPDCMRELDLRGLREVVKTAAASKPFLGICIGQQMLFEHSEEGNVPGLGILPGGVVRFPDAKMVAADGSRLKVPHMGWNEVCQRKPHPMWEGIPDNERFYFVHSYFVAPADAALVAAESDYGTRFTSAVARANIFAVQFHPEKSAQAGLKMLANFISWAP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Desulfitobacterium hafniense (strain DCB-2 / DSM 10664)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.382 kDa
Sequence
MIGIIDYGRGNLRSVEKALWKLGYPAKVLESPAELMAVKGIILPGVGAFADAMAALEEKGWIQPLIHYAHSGKPFLGICLGMQVLFEVGEEHGEHKGLGLLPGRVVRFPAGRKIPHMGWNTLHQEKPCRLLEGIPDEAYFYFVHSYYVASEEQEILAGMSDYGVPFPALVGRDNVWGAQFHPEKSSPWGLKLLENFGKWVNEDATVSSHRS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Desulfitobacterium hafniense (strain Y51)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.385 kDa
Sequence
MIGIIDYGRGNLRSVEKALWKLGYPAKVLESPAELMAVKGIILPGVGAFADAMAALEEKGWIQPLIHYAHSGMPFLGICLGMQVLFEVGEEHGEHKGLGLLPGRVVRFPAGRKIPHMGWNTLHQEKPCRLLEGIPDEAYFYFVHSYYVASEEQEILAGMSDYGVPFPALVGRDNVWGAQFHPEKSSPWGLKLLENFGKWVNEDATVSSHRS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Geobacillus kaustophilus (strain HTA426)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.824 kDa
Sequence
MIGIIDYGMGNLYSVSKALERLGCPYVLSGDKEELEQARGLILPGVGSFRDAMHILNETGLAAFIRSAVENGTPLLGICLGMQLLFDESEENGPTKGLGLLRGRVVRFPGVTKTGEPYKVPHMGWNRLRFHRPSPLLRGVEEGHVYFVHSYYVIPGDEDVVLASSEYDVDVPAVVGRGCVFGTQFHPEKSGAVGMSILNNYVGIATGRGNG

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Geobacillus sp. (strain WCH70)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.228 kDa
Sequence
MIGIIDYGMGNLYSVSKALERLRYEYIISDDPKELKNAKGLILPGVGSFKDAMHILRETGLAKFVCEAVNEGTPLLGICLGMQLLFDESEENGLTEGLGLLSGRVVRIPGVTADGNRYKVPHMGWNRLVFRHPSPLLQNVEEGHVYFVHSYYVVTDDDDVVLASSFYNVEVPAVVGKGNVYGTQFHPEKSGEIGMKILQNYASIIEGKGSM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thermobifida fusca (strain YX)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.624 kDa
Sequence
MQPRVVILDYGSGNLRSAQRAVARVGAHATISSDPHTALEADGLVVPGVGAFAACMRGLRALRGDRVIGKRLAGGRPVLGICVGMQILFERGVENDVVTEGCAEWPGTVERLDAPVIPHMGWNTVDAPAESAMFAGIDKDTRFYFVHSYGVRTWEMQTTSPHLKPPLVTWSTHGTPFVAAVENGPLWATQFHPEKSGDAGAQLLANWVATL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thermobifida fusca (strain YX)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.624 kDa
Sequence
MQPRVVILDYGSGNLRSAQRAVARVGAHATISSDPHTALEADGLVVPGVGAFAACMRGLRALRGDRVIGKRLAGGRPVLGICVGMQILFERGVENDVVTEGCAEWPGTVERLDAPVIPHMGWNTVDAPAESAMFAGIDKDTRFYFVHSYGVRTWEMQTTSPHLKPPLVTWSTHGTPFVAAVENGPLWATQFHPEKSGDAGAQLLANWVATL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Chloroflexus aggregans (strain MD-66 / DSM 9485)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.597 kDa
Sequence
MIAVINYGAGNLPNVVRALQRVGAKLTITDDPHVIRSAHAVVLPGVGATADTMASLQQLGIADVLPEVIAAGTPFLGICVGMQVLLSASEEFGPHPCLDIVRGTVRRLPDSAGKIPQIGWNQLRIMPNFSDHPLFVGIPNGADVYFVHSYYCDVIEETIVAARTEYGIAFPSVIIRDRLAAVQFHPEKSGDYGLRLLANFVAWSNASPARG

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.129 kDa
Sequence
MTKTVALLDYGSGNLRSAQRALEHVGAEVIVTSDPDICTNADGLLVPGVGAFDACMKGLRGVFGHRIIGTRLAGGRPVMGICVGMQILFDEGIEHGIQTRGCGEWSGRVERLQARILPHMGWNTVEKQPGSEMFAGLSEDERYYFVHTYGVRDWTLVTDDLTTPPLVTWAVHENDRFVAAVENGALWATQFHPEKSGDAGAQLLRNWINHI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
23.173 kDa
Sequence
MTKTVALLDYGSGNLRSAQRALERAGAEVIVSSDPEVCTNADGLLVPGVGAFDACMKGLKNVFGHRIIGQRLAGGRPVMGICVGMQILFDEGDEHGIKSAGCGEWPGKVERLQAEILPHMGWNTLEMPTNSPMFEGISPDERFYFVHSYGVRKWTLETDDLTTPPEVVWAKHENDRFVAAVENGTLWATQFHPEKSGDAGAQLLRNWINYI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Cyanothece sp. (strain PCC 7425 / ATCC 29141)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.845 kDa
Sequence
MTVIAVIDYDMGNLHSACKGLENAGAQTVVSDRPEDLFAADAVVLPGVGAFDPAMQHLRSRQLVPVIHDLIASGKPFLGICLGLQILFEHSEEGQEPGLGILAGTVKRFDPEPGLTIPHMGWNQLDLTQPGLPLWQQLELRPWLYFVHSYYVEPADLEVQAATITHGSQTVTAAIARNNLVAVQFHPEKSADAGLQILANFVSQIKAPVLV

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Cyanothece sp. (strain PCC 7424)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.874 kDa
Sequence
MAVIAVIDYDMGNLHSACKGLENAGATPKITDSARDIEQADAIVLPGVGSFDPAVYHLRSRDLEAPLKDAIASGKPFLGICLGLQILFDASEEGSQPGLGIISGVVRRFRSEPGLTIPHMGWNQLEYTQANLPLWQELPFNPYVYFVHSYYVDPIDPSVRAATVTHGSQKVTAAIAKDNIMAVQFHPEKSSSNGLKILSNFVNQIRVKAIA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Nocardia farcinica (strain IFM 10152)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.476 kDa
Sequence
MTRKSVALLDYGSGNLHSAERALVRAGADVRVTADPDAALAVDGLVVPGVGAFAACMAGLRAVRGEKIIGQRLAGGRPVLGICVGMQILFERGVEFGVETEGCAEWPGVVERLDAPVLPHMGWNTVSAPADSVLFAGMDADTRFYFVHSYAAQRWELPPNEHFAAPKLTWAEHGVRFLAAVENGPLSATQFHPEKSGDAGAQLLRNWVDSL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.065 kDa
Sequence
MPVIAVVDYEMGNLHSVCKGLEKAGATPNVTYSPKELEQADAIVLPGVGAFDPAVQHLRARGLEQPIKDAIASGKPFLGICLGLQILFESSAEGTQPGLGIIKGKVRRFRPEPDITIPHMGWNQLEMTQAKSILWEHLPSDPWVYFVHSYYVDPIDPLIRAATITHGTQTVTAAIAHENLMAVQFHPEKSSNIGLQILSNFVAQVREKIPA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.177 kDa
Sequence
MPVVAVIDYEMGNLHSVCKGLEKAGATPIITHCHQELTKADAVILPGVGAFDPAVQSLRSRDLEQPIKDTIASGKPFLGICLGLQILFESSAEGNQPGLGIIKGKVRRFVWEPGITIPHMGWNQLELTQPKSILWEHLPPQPWVYFVHSYYVDPFEPQVRAATVTHGTQTVTAAIAHENLMAVQFHPEKSSNIGLQILSNFVSQVREKIAA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Length
211 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.015 kDa
Sequence
MPVVAVIDYEMGNLHSVCKGLEKAGATPIITHSHQELTKADAVILPGVGAFDPAVQSLRSRDLEQPIKDTIASGKPFLGICLGLQILFESSAEGTQPGLGIIKGKVRRFISEPGITIPHMGWNQLELTQPKSILWEHLPPQPWVYFVHSYYVDPVEPQVRAATVTHGTQTVTAAIAHENLMAVQFHPEKSSNIGLQILSNFVSQVREKIAA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210)
Length
210 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.001 kDa
Sequence
MATIAIIDYGMGNLRSVQKGFEKVGFEAVVTADPKVVLEAEKVVLPGVGAFRDCMRNLEQGGFVEPILTVIQDGRPFLGICVGMQLLFTDSVEFGLYQGLNVIPGHVLRFPEGMRERGEDLKVPHMGWNQLSIKRRPSAFSDVEDGANVYFVHSFYAKPDEEGVVAATSSYGIDFCAAVWKDNIVATQFHPEKSQAVGLSILKNFALSKA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)
Length
210 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.466 kDa
Sequence
MIAVINYGAGNLPNAVRALEYVQAPIEVVTDPAAVRAAQAVVLPGVGATADTMRSLREMGMDSAIREVIARGTPFLGICVGMQVLAEQSEEFGLHECLGLVPGTIRRFDQGLKVPQIGWNGVQHDGSALWDGIPNGAEFYFVHSYYLATDDVALVTGRTEYGLNFPAAIARDNITAVQFHPEKSGQWGLKLLGNWVELALSRGSGVGDRA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
Length
210 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.829 kDa
Sequence
MIAILDYGMGNIHSCLKAVSLYTKDFVFTKDHSTIENSKALILPGDGHFDKAMENLNSTGLRKTIDKHVTSGKPLFGICIGFQILFESSEEIAQGSKKEQIEGLGYIKGKIKKFHGKDFKVPHIGWNRLQIRRKDKSVLLKGIGDQSFFYFIHSYRPTDAEGNAITGLCDYYQEKFPAVVEKNNIFGTQFHPEKSHTHGLKLLENFIRFI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
210 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.497 kDa
Sequence
MGYIAVVDYDMGNLHSVCKGLEKVGGNPLVTDQAHVIDGATAIVLPGVGSFDPAVQHLRARGLEEVLKTAIAKGIPFLGICLGSQLLFDSSEEGQETGLGIIPGQVKHFRSEPGLTIPHMGWNGLQFNQPDLCLWQDLPPEPQVYFVHSYYMAPLDPQVIAASTTHGSQTIAAAIAKDNVMAVQFHPEKSSTLGLKILANFVKKVALSDI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Herpetosiphon aurantiacus (strain ATCC 23779 / DSM 785 / 114-95)
Length
210 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.466 kDa
Sequence
MIAVINYGAGNLPNAVRALEYVQAPIEVVTDPAAVRAAQAVVLPGVGATADTMRSLREMGMDSAIREVIARGTPFLGICVGMQVLAEQSEEFGLHECLGLVPGTIRRFDQGLKVPQIGWNGVQHDGSALWDGIPNGAEFYFVHSYYLATDDVALVTGRTEYGLNFPAAIARDNITAVQFHPEKSGQWGLKLLGNWVELALSRGSGVGDRA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)
Length
210 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.829 kDa
Sequence
MIAILDYGMGNIHSCLKAVSLYTKDFVFTKDHSTIENSKALILPGDGHFDKAMENLNSTGLRKTIDKHVTSGKPLFGICIGFQILFESSEEIAQGSKKEQIEGLGYIKGKIKKFHGKDFKVPHIGWNRLQIRRKDKSVLLKGIGDQSFFYFIHSYRPTDAEGNAITGLCDYYQEKFPAVVEKNNIFGTQFHPEKSHTHGLKLLENFIRFI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
210 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.497 kDa
Sequence
MGYIAVVDYDMGNLHSVCKGLEKVGGNPLVTDQAHVIDGATAIVLPGVGSFDPAVQHLRARGLEEVLKTAIAKGIPFLGICLGSQLLFDSSEEGQETGLGIIPGQVKHFRSEPGLTIPHMGWNGLQFNQPDLCLWQDLPPEPQVYFVHSYYMAPLDPQVIAASTTHGSQTIAAAIAKDNVMAVQFHPEKSSTLGLKILANFVKKVALSDI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)
Length
210 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.687 kDa
Sequence
MKKVALLDYGSGNLRSAQRALERVGAEVEVTNDPDVVLAADGLLVPGVGAFDACMKGLKAVQGDRMIGQRLAGGRPVMGICVGMQIMFDSGNEHGISAAGCGQWPGNVEKLEARVLPHMGWNTVEAAQDSQLFAGLDADTRFYFVHSYGVRWWEFEGDGLTRAPLVTWAQHESDRFVAAVENGALMATQFHPEKSGDAGAQLLRNWIDLL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Photobacterium profundum (strain SS9)
Length
210 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.896 kDa
Sequence
MASTNQKVVIIDTGCANVSSVRFAIERLGYTVTISKETSVVLNADKLFLPGVGTASEAMKNLQERDLVELVKQVDKPLLGICLGMQLLGALSEEQGQNGKELVPCLHLCDAPIKKLKTGNLPLPHMGWNTITPIDNHPLFQGIPAGSYFYFVHSYAMPVSTGVNDYTIAQCEYGQPFSAAIQSGNYYGVQFHPERSSKAGSQLIKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Length
210 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
23.829 kDa
Sequence
MIAILDYGMGNIHSCLKAVSLYTKDFVFTKDHSTIENSKALILPGDGHFDKAMENLNSTGLRKTIDKHVTSGKPLFGICIGFQILFESSEEIAQGSKKEQIEGLGYIKGKIKKFHGKDFKVPHIGWNRLQIRRKDKSVLLKGIGDQSFFYFIHSYRPTDAEGNAITGLCDYYQEKFPAVVEKNNIFGTQFHPEKSHTHGLKLLENFIRFI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Moorella thermoacetica (strain ATCC 39073 / JCM 9320)
Length
210 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.59 kDa
Sequence
MRPIAIIDYGMGNLLSVQKALDRLGYPVEVTDDPGEITAAPGVILPGVGAFADAMANLQQKGLVAAIREVAERGVPLLGICLGLQLLFSTSEEGGQVAGLDLLPGEVKRLPAGIKVPHMGWNQVRFPRPGALFRGIPGGTDFYFVHSYYIVPREEEVVTGTTEYGLEFAVSIQRGNLFGVQFHPEKSSRRGLEVLKNFGELVRHAGNAGH

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.185 kDa
Sequence
MTKIAIIDYGMGNLRSVQKGFEKVGFEAVVTADPKVVLEAEKIVLPGVGAFRDCMRNLEQGGFVEPILRVIREGRPFLGICVGMQLLLTDSVEFGLYQGLNVIPGHVLRFPEGMREGGEELKVPHMGWNQLSIKRRPPAFAEVEDGANVYFVHSYYEMPDDESVIAATCTYGVEFCAAIWKDNIVATQFHPEKSQAVGLSILKNFGEMK

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Leifsonia xyli subsp. xyli (strain CTCB07)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.361 kDa
Sequence
MSRPVVVFEYGSGNVHSAVKALEAAGADVELTRDRRRAQEADGLVVPGVGAFAAVVDRLRAAHGDEIIERRLAGGRPVLGICVGMQVMFERGTEHGQETAGLGEWPGAVEPLCAGVVPHVGWNAVEAPADSVLFDGVWDERFYFVHSYAAQHWTLEATGPFPKPRVSWAEHGSRFVAAVENGPLSATQFHPEKSGSAGLRLLANWIGSL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thermosynechococcus elongatus (strain BP-1)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.609 kDa
Sequence
MSAPAIAIIDYDMGNLHSVSKALEVVGARPLISDRPAEIFAADAVVLPGVGAFDPAMARLQERELVPVIEQIIEQGMPFLGICLGLQVLFECSEEGTEPGLGIFAGKVKRFQSEPGLTIPHMGWNQLTLRPSASPLWQHLPPSPWVYFVHSYFVAPEDPSLVAATVCHGQQTVTAAIARNNLFACQFHPEKSGAVGLQLLRNFVALVKD

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Leifsonia xyli subsp. xyli (strain CTCB07)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.361 kDa
Sequence
MSRPVVVFEYGSGNVHSAVKALEAAGADVELTRDRRRAQEADGLVVPGVGAFAAVVDRLRAAHGDEIIERRLAGGRPVLGICVGMQVMFERGTEHGQETAGLGEWPGAVEPLCAGVVPHVGWNAVEAPADSVLFDGVWDERFYFVHSYAAQHWTLEATGPFPKPRVSWAEHGSRFVAAVENGPLSATQFHPEKSGSAGLRLLANWIGSL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thermosynechococcus elongatus (strain BP-1)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.609 kDa
Sequence
MSAPAIAIIDYDMGNLHSVSKALEVVGARPLISDRPAEIFAADAVVLPGVGAFDPAMARLQERELVPVIEQIIEQGMPFLGICLGLQVLFECSEEGTEPGLGIFAGKVKRFQSEPGLTIPHMGWNQLTLRPSASPLWQHLPPSPWVYFVHSYFVAPEDPSLVAATVCHGQQTVTAAIARNNLFACQFHPEKSGAVGLQLLRNFVALVKD

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.245 kDa
Sequence
MIAIIDYGMGNIRSVEQALKYIGAEYIVTSDKKEILRSDGVILPGVGAFPKAMDVLEERDLVCVLKEVCDIGKPLLGICLGMQLLFERSEELKDCSGLGLLPGEIRKLKVSYKIPHMGWNELRKEREFPLWNGLVDGSFVYYVHSYYADCPDEIVCGVSDYGMQVPGFVAKGNVFGAQFHPEKSGEIGMQILKNFQGVVEAWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus cereus (strain ZK / E33L)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.268 kDa
Sequence
MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISDYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQILKNFKGVVETWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus thuringiensis subsp. konkukian (strain 97-27)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.263 kDa
Sequence
MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRVLQEIGCSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDSSFVYYVHSYYADCPNEIVYGISDYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQMLKNFKGVVETWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus weihenstephanensis (strain KBAB4)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.14 kDa
Sequence
MIAIIDYGMGNIRSVEQALKYIGTEYIITDDKKEILRSDGVILPGVGTFPKAMGVLEEKDLVCVLKEVGSLGKPLLGICLGMQLLFEKSEELQNCNGLNLLPGVIRKLKVPYKIPHMGWNELKKEGEISLWNGVEDGSFVYYVHSYYADCPNEIVYGASEYGVKVPGFVAKGNIFGAQFHPEKSGEIGMRMLKNFKGVVEAWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Prochlorococcus marinus (strain NATL2A)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.512 kDa
Sequence
MTKIGLIDYGMGNLFSVQQAFKRFNQPLDIISDIKTLQSCDALILPGVGAFDPAMMNLRKTELVPSIIDWVNNGKPLFGICLGLQLLFEASDEGTSEGLGVIKGHIRRLPQEKDERIPHIGWSPIYKTNECPILENYPGSNWMYFVHSYSACPLEPKHTVAVTKFGKTDVSSMVWHKNTGACQFHPEKSGVAGQKIIFNWINWLKKNKF

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / NCIMB 11848 / C-107)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.187 kDa
Sequence
MSSVAVIDYGMGNLRSVSKALEQVAGKVRIDVTSNPQRIRAADRVVFPGVGAIRDCMHELRRLNLDIVVAQCAADRPFLGICLGLQALLELSEENHGVPCLGILPGRVQRFDAVKADLKVPHMGWNQAHQVRAHPLWNAIPQNCRFYFVHSYYTVPDETSLVASRTDYSTSFASALARDNIFAVQFHPEKSHTFGLQLLANFLTWNGVS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus anthracis (strain A0248)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.286 kDa
Sequence
MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISDYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQMLKNFKGVVETWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus anthracis (strain CDC 684 / NRRL 3495)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.318 kDa
Sequence
MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRMLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISDYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQMLKNFKGVVETWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus thuringiensis (strain Al Hakam)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.268 kDa
Sequence
MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISDYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQILKNFKGVVETWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus anthracis
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.286 kDa
Sequence
MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISDYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQMLKNFKGVVETWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus cereus (strain AH820)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.273 kDa
Sequence
MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGVSDYGVEVPGFVAKGNIYGAQFHPEKSGDIGMQMLKNFKGVVETWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus cereus (strain ATCC 10987 / NRS 248)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.304 kDa
Sequence
MIAIIDYGMGNIRSVEQALKHIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDVLEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISDYGVKVPGFVAKENIYGAQFHPEKSGDIGMQMLKNFKGVVESWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus cereus (strain G9842)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.204 kDa
Sequence
MIAIIDYGMGNIRSVEQALKYIGAEHIVTSDKEEILRSDGVILPGVGAFPKAMEVLEERDLVCVLKEVCDIGKPLLGICLGMQLLFERSEELKGCSGLGLLPGEIRKLKVSYKIPHMGWNELRKEREFPLWNGLVDGSFVYYVHSYYADCPDEIVCGVSDYGMQVPGFVAKGNVFGAQFHPEKSGEIGMQILKNFQGVVEAWKSSRLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus cereus (strain 03BB102)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.268 kDa
Sequence
MIAIIDYGMGNIRSVEQALKYIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDILEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISDYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQILKNFKGVVETWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus cereus (strain B4264)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.244 kDa
Sequence
MIAIIDYGMGNIRSVEQALKYIGAEYIVTSNKKEILRSDGVILPGVGAFPKAMDVLEERDLVCVLKEVCDIGKPLLGICLGMQLLFERSEELKDCSGLGLLPGEIRKLKVSYKIPHMGWNELRKEREFPLWNGLVDGSFVYYVHSYYADCPDEIVCGVSDYGMQVPGFVAKGNVFGAQFHPEKSGEIGMQILKNFQGVVEAWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus cereus (strain AH187)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.26 kDa
Sequence
MIAIIDYGMGNIRSVEQALKHIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDVLEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISEYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQMLKNFKGVVETWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-98)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.946 kDa
Sequence
MIAIIDYGMGNIRSIEQALTSIGVEHLVTDRQREIVKSDGVILPGVGAFPKAMEALEAKKLVTVLQECGKTGKPLLGICLGMQLLFEKSEEMKSSNGLGLLPGVVRKLQVPYKIPHMGWNRLTKTKEMPIWNRVADGSFVYYVHSYYAECPNDMICGTSEYGISVPGLVAKGNIFGAQFHPEKSGEIGIQMLANFKGVVKQWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus cereus (strain Q1)
Length
209 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.26 kDa
Sequence
MIAIIDYGMGNIRSVEQALKHIGAAYIVTSDKEEIFRSDGVILPGVGAFPKAMDVLEEKDLVRVLQEIGRSRKPLLGICLGMQLLFEKSEELQDCNGLSLLPGVIRKLKVPYKIPHMGWNELKKEGEIALWNGVEDGSFVYYVHSYYADCPNEIVYGISEYGVKVPGFVAKGNIYGAQFHPEKSGDIGMQMLKNFKGVVETWKSSQLSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Lactobacillus casei (strain BL23)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.323 kDa
Sequence
MIVIVDYDTGNTRNVKKALDYLGVNNQLSADPAIIMAASGLILPGVGAFKEAMKALNQRQLVPVIQAFAATGKPLLGICLGMQLLFDRSFEFGETAGLGLIPGEVVAIPTDSGLAVPHMGWNTNSLTQPDLFAAVFADQATYFVHSFYATTLPQFTLATTDYGQPLTSIVRRNNVLGTQFHPEKSGAIGLAGLKKFKEMTEDEALSRD

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Lactobacillus paracasei (strain ATCC 334 / BCRC 17002 / CIP 107868 / KCTC 3260 / NRRL B-441)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.323 kDa
Sequence
MIVIVDYDTGNTRNVKKALDYLGVNNQLSADPAIIMAASGLILPGVGAFKEAMKALNQRQLVPVIQAFAATGKPLLGICLGMQLLFDRSFEFGETAGLGLIPGEVVAIPTDSGLAVPHMGWNTNSLTQPDLFAAVFADQATYFVHSFYATTLPQFTLATTDYGQPLTSIVRRNNVLGTQFHPEKSGAIGLAGLKKFKEMTEDEALSRD

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.347 kDa
Sequence
MFAIVDYDTGNTRNLKKAFDYLQVSTILTADPQQLAAADAVILPGVGAFAAAMAALKERQLVGVLQALARSGKPVLGICLGMQLLFESSSEYGEHAGLGLLSGRVSALPTDLNVKVPQMGWNQNELRRPDSPFASIDAAYTYFVHSYYAVCPATEIVATVQHGVQVPSIVQQQNVIGMQFHPEKSGRVGLQQLAAFKEMVSANDFSSN

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Lactobacillus casei (strain BL23)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.323 kDa
Sequence
MIVIVDYDTGNTRNVKKALDYLGVNNQLSADPAIIMAASGLILPGVGAFKEAMKALNQRQLVPVIQAFAATGKPLLGICLGMQLLFDRSFEFGETAGLGLIPGEVVAIPTDSGLAVPHMGWNTNSLTQPDLFAAVFADQATYFVHSFYATTLPQFTLATTDYGQPLTSIVRRNNVLGTQFHPEKSGAIGLAGLKKFKEMTEDEALSRD

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Lactobacillus paracasei (strain ATCC 334 / BCRC 17002 / CIP 107868 / KCTC 3260 / NRRL B-441)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.323 kDa
Sequence
MIVIVDYDTGNTRNVKKALDYLGVNNQLSADPAIIMAASGLILPGVGAFKEAMKALNQRQLVPVIQAFAATGKPLLGICLGMQLLFDRSFEFGETAGLGLIPGEVVAIPTDSGLAVPHMGWNTNSLTQPDLFAAVFADQATYFVHSFYATTLPQFTLATTDYGQPLTSIVRRNNVLGTQFHPEKSGAIGLAGLKKFKEMTEDEALSRD

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Lactobacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.347 kDa
Sequence
MFAIVDYDTGNTRNLKKAFDYLQVSTILTADPQQLAAADAVILPGVGAFAAAMAALKERQLVGVLQALARSGKPVLGICLGMQLLFESSSEYGEHAGLGLLSGRVSALPTDLNVKVPQMGWNQNELRRPDSPFASIDAAYTYFVHSYYAVCPATEIVATVQHGVQVPSIVQQQNVIGMQFHPEKSGRVGLQQLAAFKEMVSANDFSSN

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Pelagibacter ubique (strain HTCC1062)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.187 kDa
Sequence
MNVTIVDYNSGNISSVINSFKEVAKDKVNIEVTSDLNKIRSSDKVVLPGQGSFKSCVDALNAINGLVETLNEFTVTNKKPLLGICVGLQMFADLGYEETETKGLGWISGKVSKIDNQNNKFKLPHIGWNEINIVKESKIFEGIKNKSHMYFVHSYEFIPDDKSVISATTDYSSNIVCSVEKENIFGTQFHPEKSDKLGLKIIENFLNL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.734 kDa
Sequence
MIVIIDYDTGNTKSISKALDFIGLQNKISSNHAEILQADGVILPGVGAFPEAMQELGRRGLDVTLKEMAESGKPMLGVCLGMQLLLESSDEHLFTKGLGLIPGHVEKLPDEPGFAVPHMGWNQLEIKRSTPLTKKLGGEYVYYVHSYYANCPNEYIIATSGYSVEVPSMINKGNIYGAQFHPEKSGQIGLEILKGFKEVTESCKSSQQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Listeria monocytogenes serotype 4b (strain CLIP80459)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.756 kDa
Sequence
MIVIIDYDTGNTKSISKALDFIGLQNKISSDKTEIAQADGVILPGVGAYPEAMQELTRRGLDKTLKEIATAGKPILGVCLGMQLLLESSNEHSYTKGLGLIPGHVEMLPDESEFAVPHMGWNQLQIKRTTPLTQNIAGEYVYYVHSYYANCPEAYIIATSGYSIDIPGMINNGNIYGAQFHPEKSGQIGLEILKGFKEVIRSCKSSQQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Listeria monocytogenes serotype 4b (strain F2365)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.756 kDa
Sequence
MIVIIDYDTGNTKSISKALDFIGLQNKISSDKTEIAQADGVILPGVGAYPEAMQELTRRGLDKTLKEIATAGKPILGVCLGMQLLLESSNEHSYTKGLGLIPGHVEMLPDESEFAVPHMGWNQLQIKRTTPLTQNIAGEYVYYVHSYYANCPEAYIIATSGYSIDIPGMINNGNIYGAQFHPEKSGQIGLEILKGFKEVIRSCKSSQQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Listeria monocytogenes serotype 4a (strain HCC23)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.76 kDa
Sequence
MIVIIDYDTGNTKSISKALDFIGLQNKISSDATEISQADGVILPGVGAYPEAMKELTRRGLDKTLKEIAATGKPILGVCLGMQLLLESSNEHSFTSGLGLIPGHVEKLPEEPEFAVPHMGWNQLQIKRATPLTKQLDGEYVYYVHSYYANCPEEYIIATSGYSIEVPGMINNGNIYGAQFHPEKSGQIGLEILKGFKEVTYSCKSSQQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.742 kDa
Sequence
MIVIIDYDTGNTKSISKALDFIGLQNKISSDATEISQADGVILPGVGAYPEAMKELTRRGLNKTLKEIAAGGKPILGVCLGMQLLLESSNEHSFTNGLGLIPGHVEKLPEDPEFAVPHMGWNQLQIKRATPLTKQLDGEYVYYVHSYYANCPEEYIIATSGYSIEVPGMINKGNIYGAQFHPEKSGQIGLEILKGFKEVTYSCKSSQQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Listeria welshimeri serovar 6b (strain ATCC 35897 / DSM 20650 / SLCC5334)
Length
208 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.082 kDa
Sequence
MIVIIDYDTGNTKSISKALDFIGLQNKISSNKTEILQADGVILPGVGAYPEAMQELIRRGLDVTLKEIAVLRKPILGVCLGMQLLLESSNEHVFTRGLGLIPGYAEKLPDEPKFVIPHMGWNQLENKRITPLTKKVDGEYVYYVHSYYANCPPEYIIATSGYSVEIPGMINNGHIYGAQFHPEKSGQIGLEILKGFKEVIRSCKSSLQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacillus clausii (strain KSM-K16)
Length
207 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.747 kDa
Sequence
MIGIIDYGMGNLHSVSKALERLAIPYFISSDGEELAKAKALILPGVGAFPDAMNILTQTNVQPFLDNWVAENKPLLGICLGMQLLFESSNEHQPTAGLGYLPGRVERFSGTTAEGHAYKVPHMGWNKLEFHRPTPLTEGVPDGYVYFVHSYVVRTETDIVVASSDYYQSVPAIVQKGQVYGMQFHPEKSSTVGMALLKRFGQLVEGN

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Aquifex aeolicus (strain VF5)
Length
207 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
23.307 kDa
Sequence
MRTVVIDYGMGNLRSVSKALEAVGFPEVVVSNDYRVASEADVLVLPGVGAFGDAMKNLEELNLVSVIRRHIEKGKPFLGICLGLQLLFEKSYEHGEHRGLGILKGEVILLPLGVKIPHIGWNQLWFKKESEILEGLKEGDFVYFVHSYRVVPEDESVVLTKTDYGEYFVSSIELDNVVAFQFHPEKSQKKGLKLLENFKRKAEKLTT

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit hisH
Organism
Cyanidioschyzon merolae (strain 10D)
Length
206 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.294 kDa
Sequence
MKVGLVDYSMGNMHSVSRAIQQANQQVCVVRSESELAQVHILVVPGVGHFDLAMKKLEQKGLRTGIAKWIAKGNPYIGICLGMHILFETSEEGKEEGLGVYKEQVKRLPVKVIPHMGWNRLECQNSECQNSEWVNWKAWPNAWAYFVHSYGVMASSQACATTTYEKIQMVAAIEKDNCFAMQFHPEKSGEFGLWLWREVMKKAASL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10)
Length
206 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.784 kDa
Sequence
MTSKSVVVLDYGSGNLRSAQRALERVGASVQVTADADAAAAADGLVVPGVGAYEACMTGLRKIGGDRIIAERVAAGRPVLGVCVGMQILFARGVEFSVETSGCGQWPGSVTRLQAPVIPHMGWNVVESGPDSVLFRGLDADTRFYFVHSYAAQQWEGSPEAVLTWSRHEGPFLAAVEDGPLSATQFHPEKSGDAGAAVLRNWIERL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
206 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.446 kDa
Sequence
MTAKSVVVLDYGSGNLRSAQRALQRVGAEVEVTADTDAAMTADGLVVPGVGAFAACMAGLRKISGERIIAERVAAGRPVLGVCVGMQILFACGVEFGVQTPGCGHWPGAVIRLEAPVIPHMGWNVVDSAAGSALFKGLDVDARFYFVHSYAAQRWEGSPDALLTWATYRAPFLAAVEDGALAATQFHPEKSGDAGAAVLSNWVDGL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
206 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.418 kDa
Sequence
MTAKSVVVLDYGSGNLRSAQRALQRVGAEVEVTADTDAAMTADGLVVPGVGAFAACMAGLRKISGERIIAERVAAGRPVLGVCVGMQILFACGVEFGVQTPGCGHWPGAVIRLEAPVIPHMGWNVVDSAAGSALFKGLDVDARFYFVHSYAAQRWEGSPDALLTWATYRAPFLAAVEDGALAATQFHPEKSGDAGAAVLSSWVDGL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Pelobacter carbinolicus (strain DSM 2380 / NBRC 103641 / GraBd1)
Length
206 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.757 kDa
Sequence
MIVIIDYGMGNLRSVQKGFEKVGYSARVTDDPAVVAQADKLVLPGVGAFRDCMDQLTAGGFVEPILRHVESGRPFLGICLGLQLLFTESEEFGHHQGLNIIPGRVVRFPGDMQEQGEVLKVPHMGWNQIDIQRPAPIFQGLDSGESVYFVHSYYVVPEDASVVAATADYGRTFCAAVWRDNVMATQFHPEKSQQVGLRILKNFGDM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Length
206 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.446 kDa
Sequence
MTAKSVVVLDYGSGNLRSAQRALQRVGAEVEVTADTDAAMTADGLVVPGVGAFAACMAGLRKISGERIIAERVAAGRPVLGVCVGMQILFACGVEFGVQTPGCGHWPGAVIRLEAPVIPHMGWNVVDSAAGSALFKGLDVDARFYFVHSYAAQRWEGSPDALLTWATYRAPFLAAVEDGALAATQFHPEKSGDAGAAVLSNWVDGL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Mycobacterium leprae (strain TN)
Length
206 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.652 kDa
Sequence
MRSKSVVVLDYGSGNLWSVQRALQRVGAAVEVTADSAAGAAADGLLVPGVGAFEACMAGLRKIAGERTIAERIVAGRPVLGVCVGMQILFARGVEFGVETTGCRQWPGVVTRLDAPVVPHMGWNVVDSASGSALFKGLDAGVRFYFVHSYAAQRWEGSSKALLTWATHQVPFLAAVEEGPLVATQFHPEKSGDAGATLLSNWLGEL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Dehalococcoides mccartyi (strain ATCC BAA-2266 / KCTC 15142 / 195)
Length
205 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.132 kDa
Sequence
MIALVDYGGGNLKSVANAIHALGYEFKLTSSPEEILSAEAVILPGVGAAADTMAGLQSKGLDKAIKELVARDIPLLAICVGMQVLFDYTAEGDNTKCLGILKGDVKRLPEGLKIPQMGWNQLKQRVSHPIFEGIPDGIDFYFVHSYYASPADPGIIGATTDYGVDFCSLVISKRLIATQFHPEKSGSYGLKLYQNFFKMALGDKK

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Dehalococcoides mccartyi (strain CBDB1)
Length
205 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.167 kDa
Sequence
MIALVDYGGGNLKSVANAIHALGYEFTLTSDPKEILSAQAVILPGVGAAADTVAGLRAKGLDEAIKELVKRDIPLLAICVGMQVLFDSTEEGGQTKCLGILAGEVKRLPDGVKIPQMGWNQLKQRVSHPLFEGIPDGTDFYFVHSYYASPADRNIIGATTDYGVDFCSLVINKRLIATQFHPEKSGSYGLKLYQNFFKMALGDKK

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)
Length
205 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.785 kDa
Sequence
MVGIVNYNIGNLASVLNALVKVGAKAQIEKEPSRLLEYDRLILPGVGAFGDAMEHLVQSGMKEAVLEFAKSGKPLLGICLGMQLLFEKSYEFGEHAGLGLLEGEIIPFDKTRMGEGYKIPQMGWNRFYAKKKSPLLKGLEEGFYLYYVHSFHAVAKREEDVLGESVYGYPFVSAIERDNVAGFQPHPEKSHDVGLRILKNFCEIG

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)
Length
205 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.785 kDa
Sequence
MVGIVNYNIGNLASVLNALVKVGAKAQIEKEPSRLLEYDRLILPGVGAFGDAMEHLVQSGMKEAVLEFAKSGKPLLGICLGMQLLFEKSYEFGEHAGLGLLEGEIIPFDKTRMGEGYKIPQMGWNRFYAKKKSPLLKGLEEGFYLYYVHSFHAVAKREEDVLGESVYGYPFVSAIERDNVAGFQPHPEKSHDVGLRILKNFCEIG

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Cutibacterium acnes (strain DSM 16379 / KPA171202)
Length
205 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.013 kDa
Sequence
MSDPVRVGIIDHGSGNLHSARRALRQVGAEVIVSNDPSALLDTDALVLPGVGALAVCMTGLRAMGGARLVRQWVDEGRPLLGICVGHQMLFERGRERDVDVKCLGVLPGVVEELPAERLPHMGWNTVTPATDSALFQGVQERFYFVHSYGVVVTGPHDHFTTATHQGATFVAAAEYGPVTSTQFHPEKSGIAGLALLTRWLNQLS

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Prochlorococcus marinus (strain MIT 9312)
Length
205 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.875 kDa
Sequence
MHKIGLIDYGMGNIHSVTKSLESLGEEIILIKNFSESKACKAIILPGVGAFDPAMINLINTDLIIDLKNWINSGKSFLGICLGLQLLFESSDEGKVQGLGILKGKIQKIPNIVNQRIPHMGWCELLPTKTNTLLELEELNNWVYFVHSYHAIPDDFSIIAAQVNYGSEKLTAMIENDNLLACQFHPEKSGKTGEKLLRRWLSNIQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)
Length
205 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.922 kDa
Sequence
MAKIGLIDYGMGNIHSVTKALESLEEEIILIKNNHQIKDCKALILPGVGSFDPAINNLSKTELIIDIKNWIKSGKSFLGICLGLQLLFESSDEGTINGLGIVKGQIKKIPQLSDQRIPHVGWCELLPTRKNSLLKVDELNNWVYFVHSYHAVPSNNNLITANVSYGSEKLTAMIERDNLMACQFHPEKSGKTGEKLLRRWIKSIQ

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)
Length
205 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.047 kDa
Sequence
MITIVDYQMGNLRSVQKAVERSGVEAEITSDASQIAAAERLILPGVGAFGDAIGEIRRRDLEKPIKDFIASGKPFLGICLGLQMLFEQGFEGGTHEGLGVLGGDVVAFELPAEFKVPHMGWNAVDVKDAGADLGIQSGTHFYFVHSYFVRPADPSVVALTCDYGGEFCAAVRRGNLMATQFHPEKSQGDGLRLMQRFATAPVEVA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
Length
205 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.72 kDa
Sequence
MTRIALLDYGMGNLHSAAKALEHVGATVDVTNDPKLIAKADKIVFPGVGAMRDCMQGMHEAGIDEVVRQAVFNKPVLAICVGMQALLESSEENGGVPALGIFEGAVKHFPDLGHLKVPHMGWNQVYQNDPAHPMWNNIDQDSRFYFVHSYYVEPKQSDLIAATCDYGLQFCTAIHKDNLFATQFHPEKSHTAGLQLLKNFVEWNI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Leptospira borgpetersenii
Length
204 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.841 kDa
Sequence
MIGILDYGVGNLKAFANVLKGLNFHHQIVKTEQELKGCEKIIMPGVGSFDSVMNKLIESGIRDVLSDLIINKKIPILGVCVGMQILASSSEEGSKSGLGWIRGRVKKFNFDRSDFSLTIPQIGWNEVNSTKENTLLKNLEKNPRFYFLHSYYIECEDKKDVIAIANYGGDFTCAVNRENIYGTQFHPEKSHHNGVALIRNFASL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Length
204 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.345 kDa
Sequence
MTEQKVVIIDTGCANVSSVKFAIERLGYDVTISKDPQVVLSADKLFLPGVGTASEAMKNLEERDLINLVKQVEKPLLGICLGMQLLGKFSQEKGQKADELVECLGLCDGEVKLLQTGDLPLPHMGWNTVSAKAGNPLFKDIEEGEYFYFVHSFAMPVGDYTIAECDYGNPFTAAVQSGNYYGVQFHPERSSKAGAKLIQNFLEL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Vibrio vulnificus (strain CMCP6)
Length
204 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.216 kDa
Sequence
MTEQKVVIIDTGCANVSSVKFAIERLGYDVTISKDPQVVLSADKLFLPGVGTASEAMKNLEERDLISLVKQVEKPLLGICLGMQLLGKVSQEKGQKADELVECLGLCDGEVKLLQTGDLPLPHMGWNTVSAKAGNPLFKGIEEGEYFYFVHSFAMPVGDYTIAECEYGNSFTAAVQSGNYYGVQFHPERSSKAGAKLIQNFLEL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Leptospira borgpetersenii
Length
204 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.841 kDa
Sequence
MIGILDYGVGNLKAFANVLKGLNFHHQIVKTEQELKGCEKIIMPGVGSFDSVMNKLIESGIRDVLSDLIINKKIPILGVCVGMQILASSSEEGSKSGLGWIRGRVKKFNFDRSDFSLTIPQIGWNEVNSTKENTLLKNLEKNPRFYFLHSYYIECEDKKDVIAIANYGGDFTCAVNRENIYGTQFHPEKSHHNGVALIRNFASL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)
Length
204 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.345 kDa
Sequence
MTEQKVVIIDTGCANVSSVKFAIERLGYDVTISKDPQVVLSADKLFLPGVGTASEAMKNLEERDLINLVKQVEKPLLGICLGMQLLGKFSQEKGQKADELVECLGLCDGEVKLLQTGDLPLPHMGWNTVSAKAGNPLFKDIEEGEYFYFVHSFAMPVGDYTIAECDYGNPFTAAVQSGNYYGVQFHPERSSKAGAKLIQNFLEL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Vibrio vulnificus (strain CMCP6)
Length
204 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.216 kDa
Sequence
MTEQKVVIIDTGCANVSSVKFAIERLGYDVTISKDPQVVLSADKLFLPGVGTASEAMKNLEERDLISLVKQVEKPLLGICLGMQLLGKVSQEKGQKADELVECLGLCDGEVKLLQTGDLPLPHMGWNTVSAKAGNPLFKGIEEGEYFYFVHSFAMPVGDYTIAECEYGNSFTAAVQSGNYYGVQFHPERSSKAGAKLIQNFLEL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100)
Length
204 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.493 kDa
Sequence
MIKIVDYGLGNIQAFANLYKRLHIPVVVARTADELAGATKIILPGVGAFDHAMARLNESGMREILESLVQKDKVPVLGICVGMQMLANSSDEGVLPGLGWVPGRVREFRNIPGLEGIAQPHMGWNDVKPVVSSGLFKGLETDARFYFLHSFFFECQNPDYSLASANYGLEFSCAVANRNVYGVQFHPEKSHDFGMTLLKNFSEI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Leptospira interrogans
Length
204 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.75 kDa
Sequence
MIGILDYGVGNLKAFANVLKDLNFRNQIVKTEQELKSCTKIIMPGVGSFDSVMDKLSESGIRDVLSDLVMSKKIPVLGVCVGMQILASSSEEGTKSGLGWIQGKVKKFNFDQSNSLLTVPQIGWNEVTSIRDNKLLLNLEKNPRFYFLHSYYMECEEDNDVIAFADYGGNFTCAVNRDNIFGTQFHPEKSHHNGVALLRNFASL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Aliivibrio fischeri (strain ATCC 700601 / ES114)
Length
204 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.462 kDa
Sequence
MTNQNVVIIDTGCSNVSSVRFAIERLGYEVTISRDPQVVLAADKLFLPGVGTASEAMKNLAERDLIELVKQVEKPLLGICLGMQLLGKLSEEKGQKADQIVDCLGLCDGEVRKLQTGDLPLPHMGWNTIKPVEGNPLFKDIPENSYFYFVHSFGMQVGDYTIASCDYGQPFTAALQAGNYYGVQFHPERSSKVGSKLIQNFLEL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Length
203 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.274 kDa
Sequence
MTQNVVIIDTGCANISSVKFAIERLGYAVTISRDPQVVLAADKLFLPGVGTASEAMKNLTERDLIELVKRVEKPLLGICLGMQLLGKLSEEKGQKADEIVQCLGLVDGEVRLLQTGDLPLPHMGWNTVQVKEGHPLFNGIEPDAYFYFVHSFAMPVGDYTIAQCEYGQPFSAAIQAGNYYGVQFHPERSSKAGARLIQNFLEL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Length
203 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.274 kDa
Sequence
MTQNVVIIDTGCANISSVKFAIERLGYAVTISRDPQVVLAADKLFLPGVGTASEAMKNLTERDLIELVKRVEKPLLGICLGMQLLGKLSEEKGQKADEIVQCLGLVDGEVRLLQTGDLPLPHMGWNTVQVKEGHPLFNGIEPDAYFYFVHSFAMPVGDYTIAQCEYGQPFSAAIQAGNYYGVQFHPERSSKAGARLIQNFLEL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Length
203 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.518 kDa
Sequence
MNKKIAIIDYDMGNLLSVKKAFDYIGANSFITSDSKEIEKSDAIILPGVGAFPDAMSSLKENGIDKTIINEAKNGKPFAGICLGMQLLFDESEEVTNTKGLGLIGGKIRKMKTEFKIPHMGWNSLNIPRECNILKGVSKGSYVYFVHSYYAELADKNNLNAYCDYGTKLPAVVSYKNIFGIQFHPEKSGEIGLTILKNFWELI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4)
Length
203 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.545 kDa
Sequence
MIGIIDYGMGNLRSVEKALKYVGYDAKITSDAKEIKNFEALILPGVGAFPDAIRVLIKTGMAEEIKIHIEKGKPFLGICLGMQLLFEKSFEGGKTEGLKIFKGNVVGLPKGNKIPHVGWNSLTIKKDTPFLKGIKNGDYVYFVHSYYVNGNEKDFEYAVTEYGIEIPAVIIKDNVFSCQFHPEKSGETGLKILKNFGEMIKCL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Lactococcus lactis subsp. lactis (strain IL1403)
Length
202 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.454 kDa
Sequence
MKKIVIIDYNIGNLQSVQAAFLRLGQETVISRDLEEIRKADALILPGVGAFPTAMNNLKKFNLIELIQERAAAGIPILGICLGMQVLFEKGYEIEERQGLGLLKGEVIPIKTNEKIPHMGWNQLNLAKASPTTHYLSDNDEVYFVHSYQATCPDDELIAYTTYGEVKIPAIVGKNNVIGCQFHPEKSGEIGRKVLKAFLEEI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Lactococcus lactis subsp. lactis (strain IL1403)
Length
202 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.454 kDa
Sequence
MKKIVIIDYNIGNLQSVQAAFLRLGQETVISRDLEEIRKADALILPGVGAFPTAMNNLKKFNLIELIQERAAAGIPILGICLGMQVLFEKGYEIEERQGLGLLKGEVIPIKTNEKIPHMGWNQLNLAKASPTTHYLSDNDEVYFVHSYQATCPDDELIAYTTYGEVKIPAIVGKNNVIGCQFHPEKSGEIGRKVLKAFLEEI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
Length
202 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.86 kDa
Sequence
MKRIVIIDYGLGNLRSVQKGLEHVGANPAISGNPEEILTADGIILPGVGAFIDAMKCLIPLKGVIAEFAESGKPMLGICLGQQVLMSSSEEGRLTGGLDLIQGRVLRFPKSELKVPHMGWNNIRIKQDHPLFKGISDGSFVYFVHSYYVDTTAENTLASCEYGLDFSASVVNSKGNVMGTQFHPEKSGTTGLKILKNFVEMC

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Length
202 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.817 kDa
Sequence
MKRIVILDYGLGNLRSVQKGLEHVGSSPAISGDPEEILAADGLILPGVGAFVDAMKCLDPIKGTIEEYARSGKPMLGICLGQQVLMSSSEEGKLTDGLDLISGKVLRFPKSELKVPHIGWNNIKIKQDHPLFEGIPDNSFVYFVHSFYVDTASENTLASCNYGLDFSASVVNSKGNVMGTQFHPEKSGAIGLKILKNFVDMC

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)
Length
202 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.861 kDa
Sequence
MKRIVIIDYGLGNLRSVQKGLEHAGASPAISGNPEEILAADGIILPGVGAFIDAMKCLVPLKKTIAEFAESGKPMLGICLGQQVLMSSSEEGRLTDGLDLIQGRVLRFPKSELKVPQMGWNNIRVKQDHPLFKGIPDGSFVYFVHSYYVDTAAENTLASCEYGLEYAASVVNSKGNVMGTQFHPEKSGATGLKILRNFVEMC

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Length
201 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.097 kDa
Sequence
MRIGIISVGPGNIMNLYRGVKRASENFEDVSIELVESPRNDLYDLLFIPGVGHFGEGMRRLRENDLIDFVRKHVEDERYVVGVCLGMQLLFEESEEAPGVKGLSLIEGNVVKLRSRRLPHMGWNEVIFKDTFPNGYYYFVHTYRAVCEEEHVLGTTEYDGEIFPSAVRKGRILGFQFHPEKSSKIGRKLLEKVIECSLSRR

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Length
201 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
23.097 kDa
Sequence
MRIGIISVGPGNIMNLYRGVKRASENFEDVSIELVESPRNDLYDLLFIPGVGHFGEGMRRLRENDLIDFVRKHVEDERYVVGVCLGMQLLFEESEEAPGVKGLSLIEGNVVKLRSRRLPHMGWNEVIFKDTFPNGYYYFVHTYRAVCEEEHVLGTTEYDGEIFPSAVRKGRILGFQFHPEKSSKIGRKLLEKVIECSLSRR

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Chlorobium chlorochromatii (strain CaD3)
Length
201 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.811 kDa
Sequence
MVFIADYGAGNLRSVLKAFEFLGIKAIVSNDPRKMAGYRKVLLPGVGAFGQAMQSLEALGFVSALLEHVDKGGHLLGICLGMQLLLSESEEMGTHKGLNLVPGKVKHFVSSSDKIPQIGWNAVDFSKQSDLFRNVADHSFFYFVHSYYCETESVEAVAATTLFAGQNFCSAIEKNGIFAVQFHPEKSADAGLKVLANFAEL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Chlorobium luteolum (strain DSM 273 / 2530)
Length
201 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.835 kDa
Sequence
MVFIADYGAGNLRSVQKAFDYLGIPATVSSDPAKMAGCRKVVLPGVGAFGQAIEALDRLGFTDALSEHVDKGGHLFGICLGMQLMLSDSEEMGSHRGLGLIPGSVRHFQSDSDKIPQIGWNSIDLKQESVLFRGIADHSFFYFVHSYYCDPLEASSIASTTWFAGKNFCSAIEKNGIFAVQFHPEKSSEAGLQVLRNFAEC

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)
Length
201 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.259 kDa
Sequence
MVFIADYGAGNLRSVHKAFDYLGIEAVVSDKASEMSRYDKVLIPGVGAFGPAMEALNRQGFDEAIREHIDKGRSVLGICLGMQLFLSESEEMGAYKGLDIVPGKVLRFTSSTDKIPQIGWNSVDYCKDSVLFRNVPDQSYFYFVHSYYCAPDEPESVAATTFFAGKKFCSAIEKNGIFAVQFHPEKSSEAGLQVLKNFAEF

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)
Length
201 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.322 kDa
Sequence
MIAIIDYGAGNIKSLQFALDKLNKHSIVTTEAAEIKQADSIILPGVGAFKDAMEAIRQLQLDSVIQEEAQKGKPILGICLGMQLFYEQSLENGDWEGLGLLKGSIKRISGEVKVPHMGWNTLDIQQASPLFDSKLENPYVYFVHSYAVSSFEENTLLASSQYGQLIPAIVQKGNITGMQFHPEKSGEFGIELLKRYEEMIR

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)
Length
201 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.85 kDa
Sequence
MKVVILDTGCANLSSVTYAIRKLGYQPEISQETATILAADKLLLPGVGTASAAMDQLKQRELIPLIKVLSQPVLGICLGMQLFAATSEESDNVAGNNVTLLEVMASPVQKMATHGLPLPHMGWNQVLPKAGHPLFRGIEDHAYFYFVHSYAIPLNTYTIAQTEYGNIFSSAIAKDNFFGVQFHPERSGAAGARLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.819 kDa
Sequence
MRMKALLIDYGSGNLRSAAKALEAAGFSVAVAQDPKAHEEADLLVLPGQGHFGQVMRAFQESGFVERVRRHLERGLPFLGICVGMQVLYEGSEEAPGVRGLGLVPGEVRRFRAGRVPQMGWNALEFGGAFAPLTGRHFYFANSYYGPLTPYSLGKGEYEGTPFTALLAKENLLAPQFHPEKSGKAGLAFLALARRYFEVL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Xanthomonas axonopodis pv. citri (strain 306)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.27 kDa
Sequence
MTDVALIDAGGANLGSVRYALERLGVDARLVRDAAGLQGAQRVILPGVGAAPEAMSRLRAQGLVEPLRELQVPLIGICLGMQLLFEHSEEGDVECLGLLPGIVRHMTPALGIRIPHMGWNQLVPMRDSALLAGLPERASAYFVHGYAAPVTADTVAACDHGGLFTAVVQNGLRCGAQFHPERSAETGARILRNFLEMSFP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.223 kDa
Sequence
MTDVALIDAGGANLGSVRYALERLGVDARVVRDAAGLHGAQRVILPGVGAAPEAMSRLRTQGLVEPLRALQVPLIGICLGMQLLFEHSEEGDVECLGLLPGIVRHMTPALGIRVPHMGWNQLVPMRESALLAGLPERASAYFVHGYAAPVTADTVAACDHGGLFTAVVQNGLRCGAQFHPERSADTGARILRNFLEMSFP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Xanthomonas campestris pv. campestris (strain 8004)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.26 kDa
Sequence
MTDLALIDAGGANLGSVRYALERLGVEARVVRDAQGLQGAERVILPGVGAAPEAMARLRAQGLIEPLQQLQVPLIGICLGMQLLFEHSEEGDVDCLGMLPGIVRHMTPALGIRVPHMGWNQLVPMRDSALLAGLPERASAYFVHGYAAPVTADTVAACDHGGLFTAVVQSGLRCGAQFHPERSADTGARILRNFLEMSFP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.26 kDa
Sequence
MTDLALIDAGGANLGSVRYALERLGVEARVVRDAQGLQGAERVILPGVGAAPEAMARLRAQGLIEPLQQLQVPLIGICLGMQLLFEHSEEGDVDCLGMLPGIVRHMTPALGIRVPHMGWNQLVPMRDSALLAGLPERASAYFVHGYAAPVTADTVAACDHGGLFTAVVQSGLRCGAQFHPERSADTGARILRNFLEMSFP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.819 kDa
Sequence
MRMKALLIDYGSGNLRSAAKALEAAGFSVAVAQDPKAHEEADLLVLPGQGHFGQVMRAFQESGFVERVRRHLERGLPFLGICVGMQVLYEGSEEAPGVRGLGLVPGEVRRFRAGRVPQMGWNALEFGGAFAPLTGRHFYFANSYYGPLTPYSLGKGEYEGTPFTALLAKENLLAPQFHPEKSGKAGLAFLALARRYFEVL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Xanthomonas axonopodis pv. citri (strain 306)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.27 kDa
Sequence
MTDVALIDAGGANLGSVRYALERLGVDARLVRDAAGLQGAQRVILPGVGAAPEAMSRLRAQGLVEPLRELQVPLIGICLGMQLLFEHSEEGDVECLGLLPGIVRHMTPALGIRIPHMGWNQLVPMRDSALLAGLPERASAYFVHGYAAPVTADTVAACDHGGLFTAVVQNGLRCGAQFHPERSAETGARILRNFLEMSFP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Xanthomonas campestris pv. vesicatoria (strain 85-10)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.223 kDa
Sequence
MTDVALIDAGGANLGSVRYALERLGVDARVVRDAAGLHGAQRVILPGVGAAPEAMSRLRTQGLVEPLRALQVPLIGICLGMQLLFEHSEEGDVECLGLLPGIVRHMTPALGIRVPHMGWNQLVPMRESALLAGLPERASAYFVHGYAAPVTADTVAACDHGGLFTAVVQNGLRCGAQFHPERSADTGARILRNFLEMSFP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Xanthomonas campestris pv. campestris (strain 8004)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.26 kDa
Sequence
MTDLALIDAGGANLGSVRYALERLGVEARVVRDAQGLQGAERVILPGVGAAPEAMARLRAQGLIEPLQQLQVPLIGICLGMQLLFEHSEEGDVDCLGMLPGIVRHMTPALGIRVPHMGWNQLVPMRDSALLAGLPERASAYFVHGYAAPVTADTVAACDHGGLFTAVVQSGLRCGAQFHPERSADTGARILRNFLEMSFP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.26 kDa
Sequence
MTDLALIDAGGANLGSVRYALERLGVEARVVRDAQGLQGAERVILPGVGAAPEAMARLRAQGLIEPLQQLQVPLIGICLGMQLLFEHSEEGDVDCLGMLPGIVRHMTPALGIRVPHMGWNQLVPMRDSALLAGLPERASAYFVHGYAAPVTADTVAACDHGGLFTAVVQSGLRCGAQFHPERSADTGARILRNFLEMSFP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Xanthomonas oryzae pv. oryzae (strain MAFF 311018)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.249 kDa
Sequence
MTDVALIDAGGANLGSVRYALERLGVEARVVRDAAGLQGAQRVILPGVGAAPEVMSRLRAQGLVAPLRELQVPLIGICLGMQLLFEHSEEGDVECLGLLPGIVRHMTPALGIRVPHMGWNRLVPMRESALLAGLPERASAYFVHGYAAPVTADTVAACDHGGLFTAIVQNGLRCGAQFHPERSADTGARILHNFLEMSFP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Xanthomonas oryzae pv. oryzae (strain KACC10331 / KXO85)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.249 kDa
Sequence
MTDVALIDAGGANLGSVRYALERLGVEARVVRDAAGLQGAQRVILPGVGAAPEVMSRLRAQGLVAPLRELQVPLIGICLGMQLLFEHSEEGDVECLGLLPGIVRHMTPALGIRVPHMGWNRLVPMRESALLAGLPERASAYFVHGYAAPVTADTVAACDHGGLFTAIVQNGLRCGAQFHPERSADTGARILHNFLEMSFP

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Xylella fastidiosa (strain 9a5c)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.275 kDa
Sequence
MTEVALIDAGGANLGSVRYALQRLGVEPRLVCDARGLEGAARVILPGVGSAPEAMARLNNQGLIEPLLRLQVPLIGICLGMQLLFEHSEEGDVPCLALLPGRVRRLTPAPSIRVPHMGWNRLLPLRASPLLAEVPEGASAYFVHSYAVPLTTAAVAACDHGGMFTAIVQQGVRCGAQFHPERSAETGARILRNFLEMDAA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Xylella fastidiosa (strain Temecula1 / ATCC 700964)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.288 kDa
Sequence
MTEVALIDAGGANLGSVRYALQRLGVEPRLVCDARGLEGAARVILPGVGSAPEAMARLNNQGLIEPLLRLQVPLIGICLGMQLLFEHSEEGDVPCLGLLPGRVRRLTPAPSIRVPHMGWNRLLPLRASPLLAEVPEGANAYFVHSYAVPLTTAAVAACDHGGMFTAIVQQGVRCGAQFHPERSAETGARILRNFLEMDAA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Length
200 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.013 kDa
Sequence
MKVAIVEYGVGNLNSVYRAVKHLGHEPVVTDDPSELHDADAVILPGVGNFRAAAEKLEETGLCDEIRELLGSVPLLGICLGMQLLMESSEESPESRGLGVFRGTCVALPNDVKTPHMGWNTVEFRTEEFREFDGEMFYFVHSYRVAPEDDVVLGETEYGERFPSVIGDRGRLIYGMQFHPEKSGPVGLKLLGEVLTGASR

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Haemophilus influenzae (strain 86-028NP)
Length
199 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.036 kDa
Sequence
MTNITIIDTGCANLSSVKFAFDRLGYNTEITFDLNKIKSADKLILPGVGTANAAMYNLQERQLIETIQNLTQPVLGICLGMQLMTEFSEEGNVPTLNLISGKTNRIPDTGLPLPQMGWNRVQFVKNCPLFDGIVQNSHFYFVHSYAVSPNEHSVAISNYGVNFSAAIAKENFYGVQFHPERSGKNGALLLKNFVEKVPF

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Length
199 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.048 kDa
Sequence
MINITIIDTGCANLSSVKFAFDRLGYNTEITFDLNKIKSADKLILPGVGTANAAMYNLQERQLIETIQNLTQPVLGICLGMQLMTEFSEEGNVPTLNLISGKTNRIPDTGLPLPQMGWNRVQFVKNCPLFDGIVQNSHFYFVHSYAVSPNEHSVAISNYGVNFSAAIAKENFYGVQFHPERSGKNGALLLKNFVEKVPF

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Haemophilus influenzae (strain 86-028NP)
Length
199 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.036 kDa
Sequence
MTNITIIDTGCANLSSVKFAFDRLGYNTEITFDLNKIKSADKLILPGVGTANAAMYNLQERQLIETIQNLTQPVLGICLGMQLMTEFSEEGNVPTLNLISGKTNRIPDTGLPLPQMGWNRVQFVKNCPLFDGIVQNSHFYFVHSYAVSPNEHSVAISNYGVNFSAAIAKENFYGVQFHPERSGKNGALLLKNFVEKVPF

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Length
199 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.048 kDa
Sequence
MINITIIDTGCANLSSVKFAFDRLGYNTEITFDLNKIKSADKLILPGVGTANAAMYNLQERQLIETIQNLTQPVLGICLGMQLMTEFSEEGNVPTLNLISGKTNRIPDTGLPLPQMGWNRVQFVKNCPLFDGIVQNSHFYFVHSYAVSPNEHSVAISNYGVNFSAAIAKENFYGVQFHPERSGKNGALLLKNFVEKVPF

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Length
199 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.533 kDa
Sequence
MKALVINYGVGNLYSISSALKRVGFEVTIDNKPRNDYDLIVFPGVGAFSAVAEFILRYRELFNDLRRSGTNFLGVCLGMQIMFEKGTEGKESNGLGWFKGIVDKINANVKLPHIGWDLVFEVKDSCELTYGLDKKYVYYVHSYVAYPTSGDYVYMKSQYGIEYPALVCDKNVVGTQFHPEKSSNTGKIFLENLKGWIKR

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)
Length
199 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.654 kDa
Sequence
MTVVVDYEMGNLLSVTKALEELGYKPSVTSDPRKILEEDLVVLPGVGAFRDAVRNLKEKGLFLALKERASLNRPILGICLGMQLFFTKSYEDGEYEGLDLIPGEVVRFQKAPKIPHMGWNNLVPVDTTHELFKNLPDYYVYFVHSYYAQTDSRYVLAYTEYGEKFPAAVRRGSIIGFQFHPEKSGPVGRQILKNLREML

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length
198 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.532 kDa
Sequence
MKALLIDYGSGNLRSAAKALEAAGFSVAVAQDPKAHEEADLLVLPGQGHFGQVMRAFQESGFVERVRRHLERGLPFLGICVGMQVLYEGSEEAPGVRGLGLVPGEVRRFRAGRVPQMGWNALEFGGAFAPLTGRHFYFANSYYGPLTPYSLGKGEYEGTPFTALLAKENLLAPQFHPEKSGKAGLAFLALARRYFEVL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length
198 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.532 kDa
Sequence
MKALLIDYGSGNLRSAAKALEAAGFSVAVAQDPKAHEEADLLVLPGQGHFGQVMRAFQESGFVERVRRHLERGLPFLGICVGMQVLYEGSEEAPGVRGLGLVPGEVRRFRAGRVPQMGWNALEFGGAFAPLTGRHFYFANSYYGPLTPYSLGKGEYEGTPFTALLAKENLLAPQFHPEKSGKAGLAFLALARRYFEVL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Pasteurella multocida (strain Pm70)
Length
198 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.988 kDa
Sequence
MQNITIINTRCANLSSVKFAFDRLGYHTEITDNIEKIQSADKLILPGVGTAKAAMQNLADLGLIEVIQSLTQPVLGICLGMQLMTDYSEEGNLDLLKLMSGKTEKLPDCQLPLPHMGWNKVHYAADHPLFAEIAQDSYFYFVHSYGVLPNPHTVATCDYGVPFSAVIQHNNFYGAQFHPERSGKAGALFLRNFVENIK

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Length
198 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.348 kDa
Sequence
MIAIIDYGSGNLRSIANAFRKIGADALVTSDPQILEAADALVLPGVGAFGSAMAKLEGLRETLLGNIMDGKPFLGICLGLQVLLSESQESPGVHGLDLIPGRVIRIPPGNKVPHMGWNQLIIVEDSQLLEGAEDEYFYFVHSYYAEPSNDVVVARTDYGVEMTAAIESDNIHATQFHPEKSGEAGLDVLRNFVEIIRA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Length
197 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.064 kDa
Sequence
MDIAILNTGCANLTSIQVAIKKLGYDSIVTSDPSIVLKSKKIFLPGVGTALAAMEQLHKKNLINTLKKLTQPILGICLGMQIFSQFSEECKGVKTIGIFDNCFTHLLKSSNLPLPHMGWNHIVFNNLHPLFKNIDKKERFYFVHSYIIPLNKYTLAKTKYGVSFSSVMQKNNFFGVQFHPEKSGDAGAQLLKNFLEI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Length
197 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.686 kDa
Sequence
MIAIVNYGVGNLKSISKALETVGAKVSVTSDPEKIKCASGVVFPGVGAFKSAIEKLNLIRDVIDSLEVPILGICLGMQLFATESTEGGVYRGLDYIPGRVVRFPPSVGKVPHMGWNTLKITREAEILDGVESGEFVYFVHSYYMQTDDEFVISKTDYGIDFPSGVERENYIGFQFHPEKSGKVGLRILENFVNIVKR

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Escherichia coli O157:H7
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.595 kDa
Sequence
MNVVILGTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.653 kDa
Sequence
MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Escherichia coli (strain K12)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.653 kDa
Sequence
MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.731 kDa
Sequence
MNVVIVDTECANLTSVRFAVERLGYSVLITDDAEQIRAADRVILPGVGTAAAAMRNLQRKQLVEPLRELTQPVLGICLGMQLLTSHSEEGDVDCLNLIPAKTKRLRDSGLPLPHMGWNTLQPTADNPLVDTSDSYCYFVHSFAVAVDEYTIASSEYGERFASMIRHNNYFGAQFHPERSGKTGEALLKRFLELTLC

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.731 kDa
Sequence
MNVVIVDTECANLTSVRFAVERLGYSVLITDDAEQIRAADRVILPGVGTAAAAMRNLQRKQLVEPLRELTQPVLGICLGMQLLTSHSEEGDVDCLNLIPAKTKRLRDSGLPLPHMGWNTLQPTADNPLVDTSDSYCYFVHSFAVAVDEYTIASSEYGERFASMIRHNNYFGAQFHPERSGKTGEALLKRFLELTLC

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Yersinia pestis
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.302 kDa
Sequence
MDVVILDTGCANLSSVTYAVQRLGYTPVISRDPAVVLRADKLFMPGVGTAHAAMEQLRQRELIELIKSCTQPVLGICLGMQLLATSSEESGGITTLGMIDAPVKKMTDFGLPLPHMGWNQITAQAGNHLFRGIPDGTYFYFVHGYAMPICPNTIAQTNYGEPFTAAVEKDNFFGVQFHPERSGAAGAQLMKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Yersinia pseudotuberculosis serotype I (strain IP32953)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.302 kDa
Sequence
MDVVILDTGCANLSSVTYAVQRLGYTPVISRDPAVVLRADKLFMPGVGTAHAAMEQLRQRELIELIKSCTQPVLGICLGMQLLATSSEESGGITTLGMIDAPVKKMTDFGLPLPHMGWNQITAQAGNHLFRGIPDGTYFYFVHGYAMPICPNTIAQTNYGEPFTAAVEKDNFFGVQFHPERSGAAGAQLMKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / JCM 11019 / NCTC 9343)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.265 kDa
Sequence
MKVAVIKYNAGNIRSVDYALKRLGVEAVVTSDKEVLKAADKVIFPGVGEAETTMLHLKESGMDHFIKELRQPVLGICLGMQLMCRFSEEGNVDCLGIFDTDVKRFAPRKHEEKVPHMGWNTISCLKSDLFKGFTRDEFVYFVHSYYVPVSEFTAAETDYIRPFSAALHKDNFYATQFHPEKSGEAGERIIKNFLEL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacteroides fragilis (strain YCH46)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.298 kDa
Sequence
MKVAVIKYNAGNIRSVDYALKRLGVEAVITSDKEVLKAADKVIFPGVGEAETTMLHLKESGMDRFIKELRQPVLGICLGMQLMCRFSEEGNVDCLGIFDTDVKRFAPRKHEEKVPHMGWNTISCLKSDLFKGFTRDEFVYFVHSYYVPVSEFTAAETDYIRPFSAALHKDNFYATQFHPEKSGEAGERIIKNFLEL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.134 kDa
Sequence
MKVAVVKYNAGNIRSVDYALKRLGVEAVITADKEILQSADKVIFPGVGEAGTTMNHLKATGLDELIKNLRQPVFGICLGMQLMCRHSEEGEVDCLNIFDVDVKRFVPQKHEDKVPHMGWNTIGKTNSKLFEGFTEEEFVYFVHSFYVPVCDFTAAETDYIHPFSAALHKDNFYATQFHPEKSGKTGERVLRNFLDL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Blochmannia floridanus
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.177 kDa
Sequence
MKIIIINTNCSNLSSVKIMLNKLGCNTIITDDPDLIIQSDKILLPGVGTANTAMKQLKKKNLIQLIKKCTQPTLGICLGMQLFGSFSNENTHTNTLNIINVPVKHMYSPTLPIPHMGWNNITILKKHDLLNGINNNHYFYFAHSYCMELNYTTIAYTNYGQPFSSVIVYKNFFGVQFHPEKSSFSGEQLIKNFLEI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Blochmannia pennsylvanicus (strain BPEN)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.085 kDa
Sequence
MNIVIIDTNCSNLLSVKTMLHRLGHNPIISDRADVISQADKLFLPGVGTASSAMKQLKKKNLITLIQNCTKPILGICLGMQLFGSISSENNGVNTLNIIHTPVKRMQYHGFPLPHMGWNTITIPKKHFLFYGIKENDYFYFAHSYCIKVCSVTISQTNYGQLFSSVIKYKNFFGVQFHPEKSGMPGQQLVKNFLEI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Salmonella choleraesuis (strain SC-B67)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.704 kDa
Sequence
MNVVILDTGCANLSSVKSAVARHGYTPVVSREAEIVLRADKLFLPGVGTAQAAMDQLRERELIDLIKACTQPVLGICLGMQLLGRRSEETRGVDLLNIIEQDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFFGVQFHPERSGAAGAQLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Salmonella paratyphi A (strain ATCC 9150 / SARB42)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.704 kDa
Sequence
MNVVILDTGCANLSSVKSAVARHGYTPVVSREAEIVLRADKLFLPGVGTAQAAMDQLRERELIDLIKACTQPVLGICLGMQLLGRRSEETRGVDLLNIIEQDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFFGVQFHPERSGAAGAQLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Salmonella typhi
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.704 kDa
Sequence
MNVVILDTGCANLSSVKSAVARHGYTPVVSREAEIVLRADKLFLPGVGTAQAAMDQLRERELIDLIKACTQPVLGICLGMQLLGRRSEETRGVDLLNIIEQDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFFGVQFHPERSGAAGAQLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.704 kDa
Sequence
MNVVILDTGCANLSSVKSAVARHGYTPVVSREAEIVLRADKLFLPGVGTAQAAMDQLRERELIDLIKACTQPVLGICLGMQLLGRRSEETRGVDLLNIIEQDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFFGVQFHPERSGAAGAQLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Shigella boydii serotype 4 (strain Sb227)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.653 kDa
Sequence
MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Shigella dysenteriae serotype 1 (strain Sd197)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.653 kDa
Sequence
MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Shigella flexneri
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.667 kDa
Sequence
MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDIVLLADKLFLPGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Shigella sonnei (strain Ss046)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.653 kDa
Sequence
MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDEDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYGEPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
21.679 kDa
Sequence
MYIVIVDTGCANLTSIKVAINNLGYNATITSESSIILKSNKIFLPGVGTASAVMDLLSKKKIINVIRECKQTILGICLGMQLFCASSEESNGVKTIGIIKTPALRLKVNNLSLPHIGWNQITFQKGHALFKNIPNNSRFYFVHSYMVPINKYTLSTTNYGINFSSIIQKDNFFGVQFHPEKSGNIGSQLLKNFLEI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
22.202 kDa
Sequence
MSIVIINTGCANLSSLKYAIQRLGYNVIITSNHKNILNAKKVFLPGVGTAFSAMKMLNQFKLKDVLYKYQQPVLGICLGMQLLCSFSSENNGIKMLDIIHAPVNILKSNKFPLPHNGWNNVSVCDENPLFIGIKNNSKFYFLHSYALYENDYMIAKTFYNVYFSAAVRKENFFGVQFHPEKSGLVGLQLLKNFLEI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.295 kDa
Sequence
MKVVILDTGCANLSSVTYAVQRLGYTPVVSREAEIVLQADKLFLPGVGTAQAAMNQLEERDLIALIKACTQPVLGICLGMQLLGTHSDESGGIPTLGIVDTPVKKMIDHGLPLPHMGWNQVIPKAGHRLFRDIDDGAYFYFVHSYAMPVCENTIAQANYGEAFTAALEKDNFFGVQFHPERSGAAGAQLLKNFLEM

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
196 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
22.101 kDa
Sequence
MIGIIDYNAGNLRSIQKAVELYDKVIITNNSEELLACDKIILPGVGNFGSAMENLAPLKETIYKIVDDRVPFLGICLGMQILFEESEEKRGIKGLGIIKGNVIKFKDVEKLPHMGWNSVKIVKDCPLFEGIKNNSYFYFVHSYHVNPDEDCIVGKTEYGREFPSVINKDNVFATQFHPEKSGKIGLKIIENFVELL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Exiguobacterium sibiricum (strain DSM 17290 / JCM 13490 / 255-15)
Length
195 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.29 kDa
Sequence
MIAIVDYGVGNIANIERALKELGEAVIVTSDLELLGQAEALVLPGVGAYAPAMARLEETGLIEFLQEQATKKPFLGICLGMQLLFESSDEDGQTEGLGILPGTVEKLPSDVRLPHMGWHQLKNHGEAVYFVHSYGAVCDPDWIVDSVEYGRLVPAIVQKDLVTGMQFHPEKSGEVGLKLLKEWRETTCNSTQQSI

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Length
195 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.323 kDa
Sequence
MIAVVDLGIGNLANVRKALGGVITSDPYAIEGAEKIVLPGVGNFGAVMEKLEPLRGVIIDAINDGKPLLGICLGLQLLFEGSEESPGKPGLGVFRGNVVRFQGVRVPHIGWNQVWQRKECPLFEGIKDGAYFYFVHSYYALPEEDVTVGVTDYESKGAKVVFTSAVCRDNVYAVQFHPEKSGRNGLRLLENFRRL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)
Length
195 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.323 kDa
Sequence
MIAVVDLGIGNLANVRKALGGVITSDPYAIEGAEKIVLPGVGNFGAVMEKLEPLRGVIIDAINDGKPLLGICLGLQLLFEGSEESPGKPGLGVFRGNVVRFQGVRVPHIGWNQVWQRKECPLFEGIKDGAYFYFVHSYYALPEEDVTVGVTDYESKGAKVVFTSAVCRDNVYAVQFHPEKSGRNGLRLLENFRRL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Length
194 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.66 kDa
Sequence
MDRIAIVDLGIGNLANVKKALKGYITSDPYEIEKADKIVLPGVGNFGAVVDKLAPIKDIIIEGINEGKPFLGICLGMQLLFEESEESPGKEGLGIFKGKVVKLKNVRTPHIGWNQVWIKKECKLFEGLKNGSYFYFVHSYHAVPQDPDIIATTTDYENAEFVSSVCFENIFGVQFHPEKSSKNGLILLRNFRRL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Mannheimia succiniciproducens (strain MBEL55E)
Length
194 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.344 kDa
Sequence
MIIIDTGCANLSSVKFAFDRLNIKAEISRDIATIKSADKLLLPGVGTAMAAMKILQDRNLIETIQNATQPMLGICLGMQLMTEYSSEGNVPTLSLMSGHTDLIPNTGLPLPHMGWNKVRYEQDHPLFAGIEQDSHFYFVHSYAVLPNEHTIATSDYGVPFSAALGCKNFYGVQFHPERSGKNGAQLLKNFVENL

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Staphylococcus aureus (strain bovine RF122 / ET3-1)
Length
192 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.364 kDa
Sequence
MIVIVDYGLGNISNVKRAIEHLGYEVVVSNKQNIIDQAETIILPGVGHFKDAMSEIKRLNLDAILAKNTDKKMIGICLGMQLMYEHSDEGDASGLGFIPGNISRIQTEYPVPHLGWNNLVSKHPMLNQDVYFVHSYQAPMSENVIAYAQYGTDIPAIVQFNNYIGIQFHPEKSGTYGLQILRQAIQGGFIND

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Staphylococcus aureus (strain COL)
Length
192 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
21.279 kDa
Sequence
MIVIVDYGLGNISNVKRAIEHLGYEVVVSNTSKIIDQAETIILPGVGHFKDAMSEIKRLNLNAILAKNTDKKMIGICLGMQLMYEHSDEGDASGLGFIPGNISRIQTEYPVPHLGWNNLVSKHPMLNQDVYFVHSYQAPMSENVIAYAQYGADIPAIVQFNNYIGIQFHPEKSGTYGLQILRQAIQGGFIND

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Azospirillum brasilense
Length
192 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
20.826 kDa
Sequence
METVALIDYGSGNLRSPAKALERAAAGCHASFQVLVTSDADAVRKADRVVLPAVGAFADCKRGLSEVPGMQLMAEGGREYGVTEGLGWIKGEVVKLEPADPTLKIPHMGWNELDIRREHPVLAGLRERAHAYFVHSYRFAVERPEDVIASADYGGPFAAVVGRDNLVGTQFHPEKSQETGLALVANFLTWRV

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Length
190 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
20.917 kDa
Sequence
MIVGVVDYTVGNIGSVLTALKRAGAVPVVVKGVEEAGRVDAVVLPGVGTYEAAYALARQFKEVVLEKPTLAICLGMQLLFESSEEGGGQGLGVFKGRVERIKARKVPNIGWRYTHVVKNSEIIAEGYYYYLHSYGVRWGENEAYTAYIKLEEKYVAAVERGHIIGVQFHPERSGRTGLELIKRFLAVAKR

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)
Length
186 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
Mass
20.693 kDa
Sequence
MIAIIDYGSGNLASVEKALHGVVTSDPYKIDMADKIVFPGAGSFSAAVSGIKNIRDIIIEKIRNGTPYLGICLGLEILFSESEEGPGTGLSFFNERLKRFKKGIHMGWNTVEFNDNIIFSGIKKGEYFYFVHRYYAPLGSYTCGKTFFNGYFTSFININNIYAVQFHPEKSGEPGLKLLRNFGELA

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Buchnera aphidicola subsp. Diuraphis noxia
Length
175 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
19.54 kDa
Fragment
single
Sequence
MGKIIILNTDCANFTSIKSAIEKLGYCCMITAEPSIVKNAKKIILPGVGTALAAMNFLSQKKLVDIIKTFTNPILGICLGMQIFCNFSEESNGVKTIGVVKTSVLHLKTNNLPLPHIGWNQISFNKCHALFKDIPNNSRFYFVHSYIVPVNKYTLSVTNYGMNFSSVIQKNNFWR

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Buchnera aphidicola subsp. Schlechtendalia chinensis
Length
174 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
19.611 kDa
Fragment
single
Sequence
MSVVIINTGCANLSSVKYAIHRLGYNPVISTSRREILRSKKIFFPGVGTAHSAMHALKKLNLLNIIKDVQQPFLGICLGMQLLGSYSEESQGMHTLDIINFPVCALKSEKFPVPHNGWNNVEVCKNNILFNGIKNNSKFYFLHSYVVHVNEYTIAKTAYNICFSAAVNKDNFWR

Gene
hisH
Protein
Imidazole glycerol phosphate synthase subunit HisH
Organism
Buchnera aphidicola subsp. Melaphis rhois
Length
173 amino acids
Function
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
Mass
19.263 kDa
Fragment
single
Sequence
MSVVIINTGCSNLSSIKYAICRLGYNPKISTSVRDILSANKILLPGVGSAYSAIRVLSESNLLNIIKKCQQPFLGICLGMQLLSAFSSEAQGLDLLSIINSPVYRLNSGSLPLPHNGWNNVEICRNNVLFEDIENHSKFYFLHSYSVDITKYTIAKTLYNTYFSAAIQKNNFW