Organism
Caenorhabditis elegans
Function
Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.
Similarity
Belongs to the WD repeat HIR1 family.
Sequence
MGDVYVTSPTFVGHDTGSILAIDCHPSGKKFITCGQKARTSNGLVVVWNAEPVLDKKKASNENVPKLLFQVESQSQSNSCRWSPDGKRFAFGSDDSSVSVWEYVGLINSMGSITGGAQNVERYKECCVLRGHSMEVLTVEWSPNGKYLASGSIDYRIIIYNARKLPDRITVLNDIQLPVKGLSWDPIGKYLASLEGDKKLRFWATDSWQCVKSVTEPFESNIEETMLTRLDWSPDGKYLMTPAAVRSGKPLIKLIQRQTWKSDQFLAGHHKGTTCVRAMPRLIEANLKNGKRMQLTCAAVGSRDKSISIWVFPGTLKPLFVINNIFNHTVMDFAWCGRNLLACSQDGTVKVIHLSESVIGEMISNEAMSDLCYQIYSIRPPRYELTDKEEDESQDSFNLSDLSSSANNASFVTCPEDVLIKRKKLVAAQQSSDIQLTKSMEDNSKENESKNSEKTMMEERNKQIDVRKDGKRRIQPVFCGTTTADPMTSLSSEGKKTVAPPPAKRKALAPAVPAKKGEVDLEDSSDSDDDDEEEEEDMEISDIESVRNKKRKVPATTSQPMLALDLKKPALRPMEPKSLKTQEGTVLMEAPEQQPKLSQHVVDRKGMFVEIDNRWKHGGVETTQIKLIKKKQQTAENEDDMMDGERRVNHECLWMAVLGSPVIIVAANKHNVVLGCGDKCLRVYRTFCGTHIVSLRLDSLPVLIGVTEHAAYALTENGRLSTWNLKLGKAVVTRQPLFDCVEASTDNSLISADVSETGVPLIVFSNGSIFTFNVSLSCWIQAITTNVLGRLTSPISDAQLSCSNGTTNSAGPLVRLLKRMRKQATAPGVAPQVVKAVKESQLEQLLHCAEQLGNPQDYQTMLMLYVETLCEGGSEKKLKNILNDLSRSGAPMQVCGLRRSALYDDVTRMIKLKQPAIAARIVAGVAASTTTKSLF