hid

Gene

hid

Protein

Cell death protein hid

Organism

Drosophila melanogaster

Length

410 amino acids

Function

Activator of apoptosis, with grim and rpr, that acts on the effector Dredd (PubMed:9740659). Seems to act genetically upstream of baculoviral anti-apoptotic p35 (PubMed:7622034). Blocks Diap2 from binding and inactivating the effector caspase Drice (PubMed:18166655).

Similarity

To D.melanogaster grim and rpr.

Mass

43.877 kDa

Sequence

MAVPFYLPEGGADDVASSSSGASGNSSPHNHPLPSSASSSVSSSGVSSASASSASSSSSASSDGASSAASQSPNTTTSSATQTPMQSPLPTDQVLYALYEWVRMYQSQQSAPQIFQYPPPSPSCNFTGGDVFFPHGHPNPNSNPHPRTPRTSVSFSSGEEYNFFRQQQPQPHPSYPAPSTPQPMPPQSAPPMHCSHSYPQQSAHMMPHHSAPFGMGGTYYAGYTPPPTPNTASAGTSSSSAAFGWHGHPHSPFTSTSTPLSAPVAPKMRLQRSQSDAARRKRLTSTGEDEREYQSDHEATWDEFGDRYDNFTAGRERLQEFNGRIPPRKKKSSNSHSSSSNNPVCHTDSQPGGTSQAESGAIHGHISQQRQVERERQKAKAEKKKPQSFTWPTVVTVFVLAMGCGFFAAR

Protein

Cell death protein hid: hid