Protein
Modification methylase HgaIB
Organism
Avibacterium paragallinarum
Function
This methylase recognizes the strands carrying the 5'-GACGC-3' sequence, causes specific methylation on C-3, and protects the DNA from cleavage by the HgaI endonuclease.
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Sequence
MKINAMSLFSSAGIGELDLHKGNLNFVVANELLKKRADTYQFFYPETKMFQGDISDEKLKREILLSAQQNNVKFLLATPPCQGLSSVGKNKHQDHFIKDNRNFLIFEVFEFIDVLNLDFILIENVPRFIEMYFPYNGQLLLLEEILKIKYASKYQIDIVILNAKDYGICQSRPRAIIKMYKYGITWKLPTIQAEISLQRAIGHLPPLEPGEVSSIKWHSAPNVKPSIIEAIRHTKPGTSAISNPIFYPKKDNGERIKGFHNTYKRMEWDKPAPARTTYSGSISSHNNIHPGRLQLDGTYSDPRVLSLLETFIVSSIDENIEFPPGSSETYIRTIIGEAIPPKLLSAICFPDGENINVK