Protein
General transcription factor IIE subunit 1
Organism
Dictyostelium discoideum
Function
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase (By similarity).
Similarity
Belongs to the TFIIE alpha subunit family.
Sequence
MSSSNNIYHILDDLVKMVIRAFYPDEYAVIIDGLLREKKRIKDEDLALRLRIQQKYVRKILMDLKGDSMVKSSDVKVEAKGPNERGSTHLLWYIDYKHIIDIVKYKLYMFRKKMESVKVQKIDVQTYKCQTCHKVYTALDIPKLLNMDTGALACEICDGELEEELNNESLTQTAKHQSDLFSQLRKIIEQLKKTEGHNIPLFARDLADLSADQGPSYTINTNSSLGMGPKPSAFPVAQGAATSHHIDPTNENIEFHVDILDTDGIEINKAVVKKENKKTGLASLPPWLLPSNSFKNRNVKSNSILNNNQQTQTSTNEQPTAVKEQIKIDQDFYINYIKTHYQEWESAPDSGDADGNGSNSGSGGSTIEGNDGGNGEHQNKKMKLDDSQTVSSMSQSDDDGKDILVRVGDNLIPITKITEHDQELMSNQEYEDYSHALYSYASKNVFDHQYQSLMSN