ggs1

Geranylgeranyl pyrophosphate synthase

384 amino acids

Catalyzes the trans-addition of the 3 molecules of isopentenyl diphosphate (IPP) onto dimethylallyl diphosphate (DMAPP) to form geranylgeranyl pyrophosphate (GGPP). GGPP is a precursor for the biosynthesis of many secondary metabolites, including the indole diterpenes nodulisporic acids (NA).

Belongs to the FPP/GGPP synthase family.

43.034 kDa

MVPNANSNTVSLQSPNAIPPRTSSTGYITPFPPAKSVLRPVPESDWLGQNNTRNRSSSTTAIPLTGMHATGPQDPARYETEDLNYTSRKTWSEQKEKVLVGPFEYLFAHPGKDFRTLMVNSFNAWLEVPQESLDVITKVVGMLHTASLLVDDVEDNSLLRRGLPVAHSIFGTAQTINSANYVYFCALQELQKLKNPEAINVYTEELLNLHRGQGMDLFWRDTLTCPTEEEYLEMVGNKTGGLFRLAIKLMQAESGTPIDCVPLVNILGIIFQIQDDYRNLSSPEYGQNKGLCEDLTEGKFSFLIIHSIRSNPSNLQLLNILKQKTTDDEVKRYAVKYMEGTGSFEYTQKVISILVDRARKMTDELDNGRGKSVGIHKILDKLVV