gcl

Gene

gcl

Protein

Glyoxylate carboligase

Organism

Escherichia coli O157:H7

Length

593 amino acids

Function

Catalyzes the condensation of two molecules of glyoxylate to give 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

Similarity

Belongs to the TPP enzyme family.

Mass

64.732 kDa

Sequence

MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLVDLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINADAAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQEMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSELDNVMEFEDIADNAADAPTETCFMHYE

Protein

Glyoxylate carboligase: gcl

Gene

gcl

Protein

Glyoxylate carboligase

Organism

Escherichia coli (strain K12)

Length

593 amino acids

Function

Catalyzes the condensation of two molecules of glyoxylate to give 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

Similarity

Belongs to the TPP enzyme family.

Mass

64.732 kDa

Sequence

Protein

Glyoxylate carboligase: gcl

Gene

gcl

Protein

Protein germ cell-less

Organism

Drosophila melanogaster

Length

569 amino acids

Function

Required for the specification of pole cells and germ cell formation. Mothers with reduced glc function give rise to sterile adult progeny that lack germ cells.

Mass

65.152 kDa

Sequence

MGQIVGSMHMNVAEVFSNRRKRKRSTDSSLGKDDPAQLDTTQPKKKKLLTTTQYIYKALFKEEKNSDVAVMALDKVWHLHKVYLSQSPYFYTMFNGTWREAQQNFIQITILDDRITVASLDAVFGSMYSDEIEIESADVISVLATATLFHLDGIIDKCAEVMVDNISPETAIQYYEAACQYGVVGVKKSTFQWFQINLLSIYSKQPNLLRHISIELMSALTASPDLYVMQTEFSLYTLLRTWMFLRLHPDYDPEDPVQRAEALKTQELLVNAGVETHAPSGDVVQWTYFTSRSEERSFLATPEGQPYVKVFQKLRTQYLTNHYMDLKIIYNDNIIPKEWLYRHIHNHWDALLRIDHGQEDCSPQQLDDEQFFENCMRCGRMLLEPGYQKWRWTGFNFGMDLILIMDSRRLNIRRHHRHEHERVLSLQTKRKFMVRTTVTSINAQRQAVFTQTSEICSLSLEKNEEVPLMVLDPKLVHPLLISINMLVVMPPNQSFKEIVPLSEEATTSLSIPISEIGANSDRPLSPSSADDSAVFIGDSEPSTPSSPAPRPRIAWSASETGAICGQLAC

Protein

Protein germ cell-less: gcl