About Products Protein Database Contact

gcH3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)
Length
268 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
30.286 kDa
Sequence
MIQITVIQIDNYGPWTVTPNPRRESDLQALQSRLYADLNLMFGAHKGLVFYTRFDNLIAITNGIDLITHKRIQESIRNRYPFTVSMVIASAETPYEAQKLATETLQEYGSAQDENRKEVLDVANELVVDGYVQIAHIDINNITGTLTDIVSAYDTYLNVNKVKLALMEELLKYNALLFFIGGDNFMAPSNGMSEEDFLDIFNRINKKYKIELKAGIGIGRTAEDASNLADIGLEKIRGKLVDKNVCTLKQDDFLESKMGMGKIYHPQF
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Methanococcus maripaludis (strain C5 / ATCC BAA-1333)
Length
266 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
29.965 kDa
Sequence
MIQITVVQIDNYGPWTVTPNPRRESDLQALQSRLYCDMNLQFGAHRGLAFYTRFDNIIAITNGIDLETHKRIQNSVKNRYPFTVSMAVASAETAYGAQKLATKTIQEYGSAQDDVRKEVLDVANEFVSNGYVQLAHVDINDITGKLTDLETAYDTYLSVQKTKLKLMEELKKYDSLGFFIGGDNFMCPCNGMSEKDFLCMFEDIKESCGIELKAGIGIGKTAEDASDLADIGLEVIREGKTDFQVYTLKQDVEERKDVTYNYMCPI
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Methanococcus maripaludis (strain C6 / ATCC BAA-1332)
Length
266 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
30.072 kDa
Sequence
MIQITVVQIDNYGPWTVTPNPRRESDLQALQSRLYCDMNLQFGAHRGLAFYTRFDNIIAITNGIDLETHKRIQNSVKNRYPFTVSMAVASAETAYEAQKLATETIQEYGSAQDDVRKEVLDVANEFVSNGYVQLAHVDINDITGKLTDLETAYDTYLSVQMTKLKLMEELKKYDSMGFFIGGDNFMCPCNGMSEKDFLCMFEDIKESCGIDLKAGIGIGKTAEDASNLADIGLEVIREGKTDFQVYTLKQEIEERKDVTYNYMCPI
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Methanococcus maripaludis (strain C7 / ATCC BAA-1331)
Length
266 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
30.058 kDa
Sequence
MIQITVVQIDNYGPWTVTPNPRRESDLQALQSRLYCDMNLQFGAHRGLAFYTRFDNIIAITNGIDLETHKRIQNSVKNRYPFTVSMAVASAETAYEAQKLATETIQEYGSAQDDVRKEVLDVANEFVSNGYVQLAHVDINDITGKLTDLETAYDTYLSVQMTKLKLMEELKKYDSMGFFIGGDNFMCPCNGMSEKDFLCMFEDIRDSCGIDLKAGIGIGKTAEDASNLADIGLEVIREGKTDFQVYTLKQSIEERKDITYNYMCPI
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Methanococcus maripaludis (strain S2 / LL)
Length
266 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
29.942 kDa
Sequence
MIQITVVQIDNYGPWTVTPNPRRESDLQALQSRLYCDMNLQFGAHKGLAFYTRFDNIIAITNGIDLETHKRIQNSVKNRYPFTVSMAVASAETAYEAQKLATKTIQEYGSAQDDVRKEVLDVANEFVSNGYVQLAHVDINDITGKLTDLETAYDTYLSVQKTKLKLMEELKKYDSLGFFIGGDNFMCPCNGMNEKDFLCMFEDIKDSCGIELKAGIGIGKTAEDASNLADIGLEVIREGKTDSQVYTLKQEIDEQKNVPYNYMCPI
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
Length
266 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
29.948 kDa
Sequence
MIQITVVQIDNYGPWTVTPNPRRESDLQALQSRLYCDMNLQFGAHKGLAFYTRFDNIIAITNGIDLETHRRIQNSIKNRYPFTVSMAIASAETPYDAQKLATEKLQEYGSAQDEVRKEVLDIANEFVSNGYVQLAHVDINDITGTLTDLETAYDTYLSVQMTKLKLMEELKKYNSMGFFIGGDNFMCPCNGMNEKDFQCMFEDIMESSGIELKAGIGIGKTAEDASNLADIGLEIIREGKTDLQVYKLKQATGETKSSPYNYMCPI
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)
Length
255 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
27.879 kDa
Sequence
MIQVTLIQIDNYGPWTVTPGPRAEPDLQTLQSRLYGDLEREFGAHGAIVFFNRFDNLIAISNGMDYDDHLLIQQSIRNRYPITISMGVGTADTAYEAQKIATKMIQNGGGAQSANRCEVLNIDSLADDDNSLVQIAHIDINDITNTLTDIETAFDTSIKVYEVLLALMDELAKIGGMCFFIGGDNYMAPTNGISKDQLREALKVVDKKTGVTLKAGIGVAKQAGRAADLADIGLEDIRAELVDDSVLLFNDLDEY
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)
Length
254 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
28.458 kDa
Sequence
MIQMTLIQIDNYGPWTVTPRPRNESDLQILQAELYADLERQFANKKGLVFFTRFDNLLAVTNGIDEEDHLRIQRSIRNRYPITISMGVGAAETPHEAQKLATIALQKEGGAQSSKRKEILAIDSLAPADENNLVQAAHIDINSVTETLTDIESAFDTNFMVNKAQHYLMTKLIKKGALLFFIGGDNFMAPCNGLSEKEIEDILVEINDEIGIGLKAGIGVGRNMEDAAYMADLGLEEIRDHDNGMWTWVIEKEY
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / NBRC 14720 / NCIMB 2260 / Gabara)
Length
253 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
27.758 kDa
Sequence
MTNTQVTLVQIDNYGPWTVTPEPRREVDLQTLQSRLYADLSQLIGNRMGYVFFTRFDNMVAVTNGLDADAHALIQESVGNRYPVTVSLSIGVDSSPAAALGTATDQLQDAGSAQDKGRTEILRGDPIQPSERTDTDVQIAHFDVNDATGKYTDQLNEFDSFINIEQGYAELMRYMRHENDSLSFFVGGDNIIAVCDGIDEAAYLDAIEHVNETVGVELKVGVGLDRTAQAAGMAAKHALETCREENTDVEFAR
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)
Length
249 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
27.645 kDa
Sequence
MIQMTLIQIDNYGPWTVTPTPRNEADLQIMQAELYADLQRQFAARQGLVFFTRFDNMLAVTNGMDLEDHRRIQKSIGNRYPITVSMGVGAAETPYDAQRNASRALQSHGGAQSEERKEVLAIDGLVDEGYVQIAHIDINGITETMTDIVPAYDTSFIVNRVQHFLMKKLIKEGALLFFIGGDNFMSPCNGLEPQGLLRIINEIDDEINVALKAGIGKAPTAEKAANLADLALEEIRGGFTYDLVHVMKE
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Sulfolobus islandicus (strain Y.N.15.51 / Yellowstone #2)
Length
232 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
27.068 kDa
Sequence
MKVLAIKLVDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYSTFPLQLRFDNFLMIVDGITNTQLIYMINDMQENLPVGIKTCLGYGKTPLEAQWNASVCLNNKEDKFKEYVDEKIAALHFDINFNTEALKYTSVYDSFLEITNIYVDLSRFLYKIGGILQYLGGDNYLGFVSTNSVNKVIEKFSDDNKIKVGIGIGQNARTAIKLATTSLEKIRNNREKTWHIEEEYH
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Sulfolobus islandicus (strain Y.G.57.14 / Yellowstone #1)
Length
232 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
27.082 kDa
Sequence
MKVLAIKLVDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYSTFPLQLRFDNFLMIVDGITNTQLIYMINDMQENLPVGIKTCLGYGKTPLEAQWNASVCLNNKEDKFKEYVDEKIAALHFDINFNTEALKYTSLYDSFLEITNIYVDLSRFLYKIGGILQYLGGDNYLGFVSTNSVNKVIEKFSDDNKIKVGIGIGQNARTAIKLATTSLEKIRNNREKTWHIEEEYH
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Sulfolobus islandicus (strain L.S.2.15 / Lassen #1)
Length
232 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
27.068 kDa
Sequence
MKVLAIKLVDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYSTFPLQLRFDNFLMIVDGITNTQLIYMINDMQENLPVGIKTCLGYGKTPLEAQWNASVCLNNKEDKFKEYVDEKIAALHFDINFNTEALKYTSVYDSFLEITNIYVDLSRFLYKIGGILQYLGGDNYLGFVSTNSVNKVIEKFSDDNKIKVGIGIGQNARTAIKLATTSLEKIRNNREKTWHIEEEYH
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Length
231 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
27.013 kDa
Sequence
MKILAIKLLDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYNTFPLQLRFDNFLMIADGITTTQLAYMINDMQENLPVRIKSCLGYGKTPLEAQWNASICLNNQDDNEIKEYTDEKIAALHFDINFNTETLKYTSVYDSFIEITNIYVNLSRFLYKIGGILQYLGGDNYLGFISTESVNKVIEEFSDDNKIKVGIGIGKNARTAIRLATTSLEKIRNNREKTWHMEEE
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Sulfolobus islandicus (strain M.16.27)
Length
230 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
26.734 kDa
Sequence
MKVLAIKLVDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYSTFPLQLRFDNLLMIVDGITNTQLIYMINDMQENLPVGIKTCLGYGKTPLEAQWNASVCLNNKEDKFKEYVDEKIAALHFDINFNTEALKYTSVYDSFLEITNIYVDLSRFLYKIGGILQYLGGDNYLGFVSTNSVNKVIEKFSDDNKIKVGIGIGQNARTAIKLATTSLEKIRNNREKTWHIEEE
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Sulfolobus islandicus (strain M.16.4 / Kamchatka #3)
Length
230 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
26.768 kDa
Sequence
MKVLAIKLVDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYSTFPLQLRFDNFLMIVDGITNTQLIYMINDMQENLPVGIKTCLGYGKTPLEAQWNASVCLNNKEDKFKEYVDEKIAALHFDINFNTEALKYTSVYDSFLEITNIYVDLSRFLYKIGGILQYLGGDNYLGFVSTNSVNKVIEKFSDDNKIKVGIGIGQNARTAIKLATTSLEKIRNNREKTWHIEEE
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Sulfolobus islandicus (strain M.14.25 / Kamchatka #1)
Length
230 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
26.768 kDa
Sequence
MKVLAIKLVDYREWTERLGYDREWLIQKIQNKFMMKIHEIASQYSTFPLQLRFDNFLMIVDGITNTQLIYMINDMQENLPVGIKTCLGYGKTPLEAQWNASVCLNNKEDKFKEYVDEKIAALHFDINFNTEALKYTSVYDSFLEITNIYVDLSRFLYKIGGILQYLGGDNYLGFVSTNSVNKVIEKFSDDNKIKVGIGIGQNARTAIKLATTSLEKIRNNREKTWHIEEE
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Length
225 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
25.964 kDa
Sequence
MKIMQINLVDYKEWTESLGYDREWKIQNFQHGFLSRLNEIAAEINSFIITYRYDSYIMLLDGVLIGKNDYILTKIKELSPVPIDICFGYGKTLLDAERNCSINMDNILLAKDEKVLVAHFDLDGFSRKRFLFDAYLEVYKIYNKLFNYAMELGGLAYYFGGDNIGIFLGVDNINKVIELANSFPNMKVGIGIGNNPREALKNAAEALHIIRIYRDRKIEIVDSKN
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Length
221 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
24.462 kDa
Sequence
MHKITLIRLRGYREWTESLGPRREHIIQTVQAKIHSALWKYFTSIGALPHHLRYDFSLALTTNIETGRVGEVVAKIKRISPVDVEFCEGVGRTPREAYENCGATPGESAGVSVVAHMDVVDSTAATNKNGPLYVYRLIQRTISTIDSGCENLGCLAFYLGGDNIMLLLPNVDAIYQVLRDVELSVRVGVGVAKKPYNAFVKATRGLDYMRVKGRVGVKVVK
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length
221 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
24.405 kDa
Sequence
MHKVVLISLRGYREWTESLGPRREHIIQKVQARIHGALWSSFTAVGALPHHFRYDYLIALANNVPRHWIDTAVAKIRRSSPVEVDYCIGMGETPLDAYRSCGEHKEGKESNAVVAHVDIVNSTDATRINGPIHTYLRALDMLRTAAGACEDVGCIAFYLGGDNMVVYLPEPKAIYALLDRVEAPVRAGVGVSPRPYTAFVKATKGLDALRAENKTGVKVVR
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Pyrobaculum calidifontis (strain JCM 11548 / VA1)
Length
221 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
24.196 kDa
Sequence
MHRVAVVTLRGYREWTESLGPRREHIIQRVQAGLHMALWRHFTSIGAFPHHTRYDAAVALVNNIPTTLIEKAVDKLKKASPVPVEYCIGTGPTPYEAYLSCGEAAGDGDNYAVLAHMDMVDSTHVTRANGPLHVYLQILHIISDLGDLCKRLGCIALYLGGDNVAVLLPEPKAAYEIAERVPVPVRVGVGVAKRPYTAFVKATKALDYLRSHGVVGVKVLK
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)
Length
221 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
24.604 kDa
Sequence
MHGIAVIELKGYREWTESLGPRREHIIQQIQAKLHATLWKSFTTVGALPHHFRYDFFIALVNNISSAAVESAVAKIARHSPVPIDFCIGTGDTPYSAYLNCRGKEVEATSFSIVAHMDIVNSTKTTKLNGPLDVYSHIVRLIDTLLDVCKEYGCLVFYLGGDNTALFLPTPDVINEIVRNIDTRVRVGVGVAKKPYNAFVKATRGLDYLRSTNREGIKIVK
Protein
GTP cyclohydrolase III: gch3

Gene
gch3
Protein
GTP cyclohydrolase III
Organism
Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / V24Sta)
Length
221 amino acids
Function
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity.
Similarity
Belongs to the archaeal-type GTP cyclohydrolase family.
Mass
23.94 kDa
Sequence
MHGVVVVELKGYREWTESLGPRREHIIQQVQSRIQAAVWRSFTAVGALPHHFRYDFYIALVNGVSLDLVKRAVEKAARASPVGAGFCLGVGETPYEAYLRCGGGGGGAASPAVVAHMDVINSTEATRRNGPLDVYLKVVKLLGQLGERCKDLGCMAFYLGGDNIALFLPSPNAIYSILDGVDLRVRVGVGVAKRPYNAFVRATWALDRLRSAGREGVEVVK
Protein
GTP cyclohydrolase III: gch3

Gene
gcH3
Protein
Histone H3-like 2
Organism
Lilium longiflorum
Length
100 amino acids
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Similarity
Belongs to the histone H3 family.
Mass
11.396 kDa
Sequence
MARMKHTARMSTGGKAPRKQLASKALRKAPPPPTKGVKQPTTTTSGKWRFARFHRKLPFQGLVRKIWQDLKTHLRFKNHSVPPLEEVTEVYPCQTIGGCY
Protein
Histone H3-like 2: gcH3