GATA3

GATA-binding factor 3

444 amino acids

Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes.

48.197 kDa

MEVSTDQPRWVSHHHPAVLNGQHPDSHHPTLGHTYMDPTQYPLAEEVDVLFNIDGQGNPVPPYYGNSVRATVQRYPTAHHGSQVCRPPLLHGSLPWLDGSKALSSHHSASPWNLSPFSKTSIHHSSPGPLSVYPPASSSTLSAGHSSPHLFTFPPTPPKDVSPDPSISTPGSTGSTRQDEKECIKYQVSLADTMKLESSHSRSSMASLGGATSSAHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDNLEDFPKSSSFNPAALSRHMSSISHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG

GATA3

Trans-acting T-cell-specific transcription factor GATA-3

443 amino acids

Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.

47.916 kDa

MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFNIDGQGNHVPPYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLSGGHASPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDEKECLKYQVPLPDSMKLESSHSRGSMTALGGASSSTHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDSLEDFPKNSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG

Gata3

Trans-acting T-cell-specific transcription factor GATA-3

443 amino acids

Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.

47.968 kDa

MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLGHSYMEAQYPLTEEVDVLFNIDGQGNHVPSYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALSSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLAAGHSSPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDEKECLKYQVQLPDSMKLETSHSRGSMTTLGGASSSAHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDALEDFPKSSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSGLSFGPHHPSSMVTAMG

GATA3

Trans-acting T-cell-specific transcription factor GATA-3

443 amino acids

Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.

47.916 kDa

MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFNIDGQGNHVPPYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLSGGHASPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDEKECLKYQVPLPDSMKLESSHSRGSMTALGGASSSTHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDSLEDFPKNSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG

Gata3

Trans-acting T-cell-specific transcription factor GATA-3

443 amino acids

Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.

47.968 kDa

MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLGHSYMEAQYPLTEEVDVLFNIDGQGNHVPSYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALSSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLAAGHSSPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDEKECLKYQVQLPDSMKLETSHSRGSMTTLGGASSSAHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDALEDFPKSSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSGLSFGPHHPSSMVTAMG

GATA3

Trans-acting T-cell-specific transcription factor GATA-3

443 amino acids

Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses (By similarity).

47.807 kDa

MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLGHSYMDPAQYPLPEEVDVLFNIDGQGNHVPSYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLSAGHSSPHLFTFPPTPPKDVSPDPSLSTPGSAGSGRQDEKECIKYQVPLPDSMKLESAHPRGSMATLGGAAASAHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDALEDFPKSSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG

gata3

Transcription factor GATA-3

438 amino acids

47.59 kDa

MEVSPEQHRWVTHHTVGQHPETHHPGLGHSYMDPSQYQLAEDVDVLFNIDGQSNHPYYGNPVRAVQRYPPPPHSSQMCRPSLLHGSLPWLDGGKSIGPHHSTSPWNLGPFPKTSLHHSSPGPLSVYPPASSSSLSAGHSSPHLFTFPPTPPKDVSPDPAISTSGSGSSVRQEDKECIKYQVSLAESMKLDSAHSRSMASIGAGASSAHHPIATYPSYVPDYGPGLFPPSSLIGGSSSSYGSKTRPKTRSSSEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKSKKSHDSMEDFSKSLMEKNSSFSPAALSRHMTSFPPFSHSGHMLTTPTPMHPSSSLPFASHHPSSMVTAMG

gata3

Transcription factor GATA-3

438 amino acids

47.59 kDa

MEVSPEQHRWVTHHTVGQHPETHHPGLGHSYMDPSQYQLAEDVDVLFNIDGQSNHPYYGNPVRAVQRYPPPPHSSQMCRPSLLHGSLPWLDGGKSIGPHHSTSPWNLGPFPKTSLHHSSPGPLSVYPPASSSSLSAGHSSPHLFTFPPTPPKDVSPDPAISTSGSGSSVRQEDKECIKYQVSLAESMKLDSAHSRSMASIGAGASSAHHPIATYPSYVPDYGPGLFPPSSLIGGSSSSYGSKTRPKTRSSSEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKSKKSHDSMEDFSKSLMEKNSSFSPAALSRHMTSFPPFSHSGHMLTTPTPMHPSSSLPFASHHPSSMVTAMG

gata3

GATA-binding factor 3

435 amino acids

47.52 kDa

MEVSAEQPRWVSHPHHPALLNGQHTDSHHQVHNYMDPSQYPPPEDMDVLFNIDAQGNHVPSYYSNSVRTVPRYPPPHHGSLVCHPSILQSWTDGRKSLGGPHAASAWNLPFTKPSIHHNSPGGLSVYPPASSASLATGHSSPHLFTFPPTPPKDVSPDPSISTSGSTSSSRHEEKECVVSKYQVSLGDTGMKLESLHPRNSMSGIGGVSAHHPITTYPDYYGAGLFQPGSILDGSPTHFSSNARPKTRSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKSKKFHDSLEDYPKSSSFSPAALSRHMSSLSHIPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG

gata3

GATA-binding factor 3

435 amino acids

47.52 kDa

MEVSAEQPRWVSHPHHPALLNGQHTDSHHQVHNYMDPSQYPPPEDMDVLFNIDAQGNHVPSYYSNSVRTVPRYPPPHHGSLVCHPSILQSWTDGRKSLGGPHAASAWNLPFTKPSIHHNSPGGLSVYPPASSASLATGHSSPHLFTFPPTPPKDVSPDPSISTSGSTSSSRHEEKECVVSKYQVSLGDTGMKLESLHPRNSMSGIGGVSAHHPITTYPDYYGAGLFQPGSILDGSPTHFSSNARPKTRSSTEGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKSKKFHDSLEDYPKSSSFSPAALSRHMSSLSHIPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG

GATA3

GATA transcription factor 3

269 amino acids

Transcriptional activator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters. May be involved in the regulation of some light-responsive genes.

Belongs to the type IV zinc-finger family. Class A subfamily.

30.468 kDa

MELWTEARALKASLRGESTISLKHHQVIVSEDLSRTSSLPEDFSVECFLDFSEGQKEEEEEVVSVSSSQEQEEQEHDCVFSSQPCIFDQLPSLPDEDVEELEWVSRVVDDCSSPEVSLLLTQTHKTKPSFSRIPVKPRTKRSRNSLTGSRVWPLVSTNHQHAATEQLRKKKQETVLVFQRRCSHCGTNNTPQWRTGPVGPKTLCNACGVRFKSGRLCPEYRPADSPTFSNEIHSNLHRKVLELRKSKELGEETGEASTKSDPVKFGSKW