fps

Gene

fps

Protein

Farnesyl diphosphate synthase

Organism

Dictyostelium discoideum

Length

382 amino acids

Function

Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a sterol precursor. Involved in the inhibition of cell growth.

Similarity

Belongs to the FPP/GGPP synthase family.

Mass

43.59 kDa

Sequence

MNNQSLQRAAMISEHLAPTSELNMNQTSAPIKTAKEELADFVEIFPILTNEILKELPGMDMPPQTIAWVEKMINVNVSGGKMNRGLTVLHSLQLLVEGRQLSRSEIFLANVLGWCVEWLQAFFLVADDIMDQSITRRGQPCWYRQANPISNNGTIGSIAINDSFILESCIYILIKKYFRNEPYYADILDIFHETSYQTELGQLLDLTTQPNRGDFSLFTLNTYRRIVKYKTAYYSFYLPVALAMLMAGITSTPAFSTAKDILLPMGEFFQVQDDFLDCYGSPAVIGKIGRDIEENKCSWMICQAILNGTPEQINLLKKHYGLDNPTDVELVKKIYGEIGLKKIFKDYEDESYAFLISKIKSVRIMPQEVFIKLLSKIYKRDL

Protein

Farnesyl diphosphate synthase: fps

Gene

fps

Protein

Farnesyl diphosphate synthase

Organism

Dictyostelium discoideum

Length

382 amino acids

Function

Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a sterol precursor. Involved in the inhibition of cell growth.

Similarity

Belongs to the FPP/GGPP synthase family.

Mass

43.59 kDa

Sequence

Protein

Farnesyl diphosphate synthase: fps

Gene

FPS

Protein

Farnesyl pyrophosphate synthase

Organism

Zea mays

Length

350 amino acids

Function

Similarity

Belongs to the FPP/GGPP synthase family.

Mass

40.014 kDa

Sequence

MAAGGNGAGGDTRAAFARIYKTLKEELLTDPAFEFTEESRQWIDRMVDYNVLGGKCNRGLSVVDSYKLLKGADALGEEETFLACTLGWCIEWLQAFFLVLDDIMDDSHTRRGQPCWFRVPQVGLIAANDGIILRNHISRILRRHFKGKPYYADLLDLFNEVEFKTASGQLLDLITTHEGEKDLTKYNITVHGRIVQYKTAYYSFYLPVACALLLSGENLDNYGDVENILVEMGTYFQVQDDYLDCYGDPEFIGKIGTDIEDYKCSWLVVQALERADESQKRILFENYGKKDPACVAKVKNLYKELDLEAVFQEYENESYKKLIADIEAQPSIAVQKVLKSFLHKIYKRQK

Protein

Farnesyl pyrophosphate synthase: FPS

Gene

FPS

Protein

Farnesyl pyrophosphate synthase

Organism

Panax ginseng

Length

342 amino acids

Function

Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (By similarity). Component of the triterpene saponins (e.g. ginsenosides or panaxosides) and phytosterols biosynthetic pathways (PubMed:24933610, PubMed:27746309, PubMed:29378087). Promotes the accumulation of ginsenosides (PubMed:24933610).

Similarity

Belongs to the FPP/GGPP synthase family.

Mass

39.627 kDa

Sequence

MSDLKTRFLEVYSVLKSELLNDPAFEFTDDSRQWVERMLDYNVPGGKLNRGLSVIDSYKLLKEGKELSDDEIFLSSALGWCIEWLQAYFLVLDDIMDSSHTRRGQPCWFRLPKVGMIAVNDGILLRNHIPRILKKHFRQKPYYVDLLDLFNEVEFQTASGQMIDLITTLVGEKDLSKYSLPIHRRIVQYKTAYYSFYLPVACALLMSGEDLEKHTNVKDILIEMGTYFQVQDDYLDCFGAPEVIGKIGTDIEDFKCSWLVVKALELSNEEQKKFLHENYGKDDPASVAKVKELYNTLKLQDVFAEYESKSYDKLIKFIEAHPSQAVQAVLKSFLGKIYKRQK

Protein

Farnesyl pyrophosphate synthase: FPS

Gene

FPS

Protein

Farnesyl pyrophosphate synthase

Organism

Panax ginseng

Length

342 amino acids

Function

Similarity

Belongs to the FPP/GGPP synthase family.

Mass

39.627 kDa

Sequence

Protein

Farnesyl pyrophosphate synthase: FPS

Gene

fps

Protein

Farnesyl diphosphate synthase

Organism

Micrococcus luteus

Length

291 amino acids

Similarity

Belongs to the FPP/GGPP synthase family.

Mass

32.362 kDa

Sequence

MLQEKLTMNRDFLNLINESLLNKYHPAQSRLHEAINYSLSAGGKRIRPLLVLTTLDSLGGNAHDGLPFGIALEMIHTYSLIHDDLPAMDNDDYRRGKLTNHKRFDEATAILAGDALLTDAFQCILNTQLNAEIKLSLINLLSTASGSNGMVYGQMLDMQGEHKTLTLNELERIHIHKTGELIRAAIVSAGIIMNFNDAQIEQLNIIGKNVGLMFQIKDDILDVEGSFENIGKTVGSDLNNDKSTYVSLLGLEASKQLLNDKLTETYDALKTLQPINDNLKTLITYIVERNK

Protein

Farnesyl diphosphate synthase: fps