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foxd3-b

Gene
foxd3-b
Protein
Forkhead box protein D3-B
Organism
Xenopus laevis
Length
371 amino acids
Function
Transcriptional repressor that is an essential upstream regulator of neural crest determination and mesoderm induction. Functions by recruiting the transcriptional corepressor tle4. Also acts in a negative auto-regulator loop by inhibiting the transcription of its own gene.
Mass
40.148 kDa
Sequence
MTLSSSGSASDMSGQTVLSADDADIDVVGEGDEALDKDSECESPVGHHDEVDALGGKEIPRSPSGSSTDAEGKGESQQQQQEGIQNKPKNSVVKPPYSYIALITMSILQSPQKKLTLSGICEFISSRFPYYREKFPAWQNSIRHNLSLNDCFIKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRQQQDTLREQTALMMQSFGAYSLASPYGRHYGLHPAAYTHPAALQYPYIPPVGPMLPPAVPLLPSSELTRKAFSSQLSPSLQLQLSSLSSTAASIIKSEPSSRPSFSIENIIGVSAASSVAPQTFLRPPVTVQSALMSHQPLVLSRSTAAIGPILSVPTNLISGQFLPTAATAVAKWPAQ