Protein
Dihydrofolate reductase 2
Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Sequence
MCMKLSLIAAVAANGVIGAGGDIPWQYPEDLTHFKETTVGHPVIMGRRTFESIRRDLDGPLPERLNIVLTTTPHQLPDSVTAVTSTTAAVAEAADSDASTTYVIGGATVYEQFLPQADELILTELAAAFDGDTVFPTVDWSNWTEMERTTHSEFAIVRYTRTSSDSA