About Products Protein Database Contact

folA

Gene
folA
Protein
Dihydrofolate reductase
Organism
Mycoplasma pulmonis (strain UAB CTIP)
Length
179 amino acids
Similarity
Belongs to the dihydrofolate reductase family.
Mass
21.491 kDa
Sequence
MTMNLIQLLKGKWRFKMIISIWAMTKEGLIGKDNQMPWHIKEEFQHFRRQTLHKTLIMGKNTFFSLPKVFDKRKMYVLSHEKDFKIDHPDVEVIYDYKDLLKEYANNDKKDIYVAGGLYVYQQLIPLSDILIVSIVKGSYEGNKYLSVDFSNFVQYKQPEIYDQFSVYYYKKKDQKNSI

Gene
folA
Protein
Dihydrofolate reductase
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Length
169 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
19.367 kDa
Sequence
MAKVIFVLAMDVSGKIASSVESWSSFEDRKNFRKITTEIGNVVMGRITFEEIGRPLPERLNVVLTRRPKTSNNPSLVFFNGSPADVVKFLEGKGYERVAVIGGKTVFTEFLREKLVDELFVTVEPYVFGKGIPFFDEFEGYFPLKLLEMRRLNERGTLFLKYSVEKSHR

Gene
folA
Protein
Dihydrofolate reductase
Organism
Lactococcus lactis subsp. lactis (strain IL1403)
Length
168 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
19.729 kDa
Sequence
MIIGIWAEDEAGLIGEADKMPWSLPAEQQHFKETTMNQVILMGRKTFEGMNKRVLPGRISIILTRDETYQSDNEKVLIMHSPKEVLDWYHKQNKDLFITGGAEILALFESELELLYRTVVHEKFKGDTYFPSTFDFGRFKLVSEKFHDKDERNSYTFTIKKYEKVKQP

Gene
folA
Protein
Dihydrofolate reductase
Organism
Mycobacterium leprae (strain TN)
Length
165 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.509 kDa
Sequence
MTVVGLIWAQSTTGVIGRDGGMPWRVPEDLTRFKQLTMGHPVVMGRRTWDSLPVGVRPLPGRRNIVLSRQIDFMAEGAEVFGSLEETISNLETEPEMWVIGGEQIYRLALPLATRCGVTEVDTYLLHEDDDVLAPVLDDTWVGVTGEWLVSCSGLRYRLHSYHRS

Gene
folA
Protein
Dihydrofolate reductase
Organism
Lactobacillus casei
Length
163 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.439 kDa
Sequence
MTAFLWAQDRDGLIGKDGHLPWHLPDDLHYFRAQTVGKIMVVGRRTYESFPKRPLPERTNVVLTHQEDYQAQGAVVVHDVAAVFAYAKQHPDQELVIAGGAQIFTAFKDDVDTLLVTRLAGSFEGDTKMIPLNWDDFTKVSSRTVEDTNPALTHTYEVWQKKA

Gene
folA
Protein
Dihydrofolate reductase
Organism
Neisseria gonorrhoeae
Length
162 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
17.731 kDa
Sequence
MLKITIIAACAENLCIGAGNAMPWHIPEDFAFFKVYTLGKPVIMGRKTWESLPVKPLPGRRNIVISRQADYCAAGAETVASLEVALALCAGAEEAVIMGGAQIYGQAMPLATDLRITEVDLSVEGDAFFPEIDRTHWREAERTERRVSSKGVAYTFVHYLGK

Gene
folA
Protein
Dihydrofolate reductase
Organism
Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)
Length
162 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
17.682 kDa
Sequence
MLKITLIAACAENLCIGAGNAMPWHIPEDFAFFKAYTLGKPVIMGRKTWESLPVKPLPGRRNIVISRQADYCAAGAETAASLEAALALCAGAEEAVIMGGAQIYGQAMPLATDLRITEVDLSVEGDAFFPAIDRTHWKEAERTERRVSSKGTSYAFVHYLRY

Gene
folA
Protein
Dihydrofolate reductase
Organism
Neisseria meningitidis serogroup B (strain MC58)
Length
162 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
17.752 kDa
Sequence
MLKITLIAACAENLCIGAGNAMPWHIPEDFAFFKAYTLGKPVIMGRKTWESLPVKPLPGRRNIVISRQADYCAAGAETAASLEAALALCAGAEEAVIMGGAQIYGQAMPLATDLRITEVDLSVEGDAFFPAIDRTHWKEAERTERRVSSKGTRYAFVHYLRY

Gene
folA
Protein
Dihydrofolate reductase
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Length
161 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
17.872 kDa
Sequence
MTMVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS

Gene
folA
Protein
Dihydrofolate reductase
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
161 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
17.872 kDa
Sequence
MTMVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS

Gene
folA
Protein
Dihydrofolate reductase
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
161 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
Similarity
Belongs to the dihydrofolate reductase family.
Mass
17.872 kDa
Sequence
MTMVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVGSLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS

Gene
folA
Protein
Dihydrofolate reductase
Organism
Staphylococcus epidermidis
Length
161 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.417 kDa
Sequence
MTLSIIVAHDKQRVIGYQNQLPWHLPNDLKHVKQLTTGNTLVMGRKTFNSIGKPLPNRRNVVLTNQASFHHEGVDVINSLDEIKELSGHVFIFGGQTLFEAMIDQVDDMYITVIDGKFQGDTFFPPYTFENWEVESSVEGQLDEKNTIPHTFLHLVRRKGK

Gene
folA
Protein
Dihydrofolate reductase
Organism
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Length
161 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.417 kDa
Sequence
MTLSIIVAHDKQRVIGYQNQLPWHLPNDLKHVKQLTTGNTLVMGRKTFNSIGKPLPNRRNVVLTNQASFHHEGVDVINSLDEIKELSGHVFIFGGQTLFEAMIDQVDDMYITVIDGKFQGDTFFPPYTFENWEVESSVEGQLDEKNTIPHTFLHLVRRKGK

Gene
folA
Protein
Dihydrofolate reductase
Organism
Staphylococcus epidermidis (strain ATCC 12228)
Length
161 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.417 kDa
Sequence
MTLSIIVAHDKQRVIGYQNQLPWHLPNDLKHVKQLTTGNTLVMGRKTFNSIGKPLPNRRNVVLTNQASFHHEGVDVINSLDEIKELSGHVFIFGGQTLFEAMIDQVDDMYITVIDGKFQGDTFFPPYTFENWEVESSVEGQLDEKNTIPHTFLHLVRRKGK

Gene
folA
Protein
Dihydrofolate reductase
Organism
Mycoplasma genitalium (strain ATCC 33530 / G-37 / NCTC 10195)
Length
160 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.966 kDa
Sequence
MLIAIWAMTQEGLIGNNNTLPWMIKQELAHFKKTTLFQALLMGRKTYESLPKVFEKRTIFLLSKDQNYRFEEKGSEVKVINDFWPLIKSYQANKEKDLFICGGKSVYEQTINECDQLIVSIIKKKYKGDQFLKVDLSKFVLNEVVEFEEFNVNYYRKKQQ

Gene
folA
Protein
Dihydrofolate reductase
Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Length
160 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.511 kDa
Sequence
MVKAIWAMDQNGLIGNGNSLPWRIKAELQHFRQTTLHQDVLMGSATYLSLPPVFSERNVYILTRNLNFNPPDKGCLTKVIHEYENFIQPYLHHPDKHLYICGGAQVYEQLIPRCDALIVSTIFGKYTGDKYLKVDFSPFELTKEISFAEFKVAYYHKIAR

Gene
folA
Protein
Dihydrofolate reductase
Organism
Shigella flexneri
Length
159 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
17.999 kDa
Sequence
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR

Gene
folA
Protein
Dihydrofolate reductase
Organism
Staphylococcus aureus (strain COL)
Length
159 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.251 kDa
Sequence
MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK

Gene
folA
Protein
Dihydrofolate reductase
Organism
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Length
159 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.251 kDa
Sequence
MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK

Gene
folA
Protein
Dihydrofolate reductase
Organism
Staphylococcus aureus (strain N315)
Length
159 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.251 kDa
Sequence
MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK

Gene
folA
Protein
Dihydrofolate reductase
Organism
Staphylococcus aureus (strain MRSA252)
Length
159 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.251 kDa
Sequence
MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK

Gene
folA
Protein
Dihydrofolate reductase
Organism
Staphylococcus aureus (strain MSSA476)
Length
159 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.233 kDa
Sequence
MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVVGVDVIHSIEDIYQLPGHVFIFGGQILFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK

Gene
folA
Protein
Dihydrofolate reductase
Organism
Staphylococcus aureus
Length
159 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.251 kDa
Sequence
MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK

Gene
folA
Protein
Dihydrofolate reductase
Organism
Staphylococcus aureus (strain MW2)
Length
159 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.233 kDa
Sequence
MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVVGVDVIHSIEDIYQLPGHVFIFGGQILFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK

Gene
folA
Protein
Dihydrofolate reductase
Organism
Ureaplasma parvum serovar 3 (strain ATCC 700970)
Length
156 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
18.534 kDa
Sequence
MLKLIWCQTLNGGISKNNKLPWYIKEELDHFYKTTKNHKIIMGKNTFDSLDQKPLNNRTNIIFSSIMQTPEDESYFVTNDFQQVLNDAKKEDIFIIGGKELFDIFLAYADVLIVSVLKDYYDCDLYMKVDYNNFNLDKQDVYDNFIVNYYSNKKEK