fmrO

Gene

fmrO

Protein

16S rRNA (guanine(1405)-N(7))-methyltransferase

Organism

Micromonospora olivasterospora

Length

293 amino acids

Function

Specifically methylates the N(7) position of guanine 1405 in 16S rRNA (By similarity). Confers resistance to aminoglycosides.

Similarity

Belongs to the methyltransferase superfamily. Aminoglycoside resistance family.

Mass

30.922 kDa

Sequence

MLAAAKYRNLDPAFVERLAQEAAERFRDRGQAVKYAKRKLHQAFGAFVAGTPAQAVAACVAKIAAGAEPKEAGREAMRAHASSAERVDWLEPFYERVAQWCGPASSVIDLACGLNPLAVPWMALAPGATYACYDVDRTMAEALRALGTVYPVRVNAAAVDLVAAVPAAGVDVALVLKTLTTVEQQRGGRRVAEYRRELTAVQHHSDGARSLSGRRGYADDPDAIVQRAVHGTGYEVVDEAAFGTEALYHLVPLAGTAGRPAPAEGAAEPGATRPVVDVPATARPDADRVDPTG

Protein

16S rRNA (guanine(1405)-N(7))-methyltransferase: fmrO