fimD

Outer membrane usher protein FimD

878 amino acids

Involved in the export and assembly of FimA fimbrial subunits across the outer membrane.

Belongs to the fimbrial export usher family.

96.482 kDa

MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLVVACAFAAQAPLSSADLYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVAGMNLLADDACVPLTTMVQDATAHLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDRSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKTRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR

fimD

Outer membrane usher protein FimD

870 amino acids

Involved in the export and assembly of FimA fimbrial subunits across the outer membrane.

Belongs to the fimbrial export usher family.

95.128 kDa

MKKTTWFAGRFPGYVSPLSSVALSVLAALCPLTSRGESYFNPAFLSADTASVADLSRFEKGNHQPPGIYRVDIWRNDEFVATQDIRFEAGAVGTGDKSGGLMPCFTPEWIKRLGVNTAAFPVSDKGVDTTCIHLPEKIPGAEVAFDFASMRLNISLPQASLLNSARGYIPPEEWDEGIPAALINYSFTGSRGTDSDSYFLSLLSGLNYGPWRLRNNGAWNYSKGDGYHSQRWNNIGTWVQRAIIPLKSELVMGDSNTGNDVFDSVGFRGARLYSSDNMYPDSLQGYAPTVRGIARTAAKLTIRQNGYVIYQSYVSPGAFAITDLNPTSSSGDLEVTVDEKDGSQQRYTVPYSTVPLLQREGRVKYDLVAGDFRSGNSQQSSPFFFQGTVIAGLPAGLTAYGGTQLADRYRAVVVGAGRNLGDWGAVSVDVTHARSQLADDSTHQGQSLRFLYAKSLNNYGTNFQLLGYRYSTRGFYTLDDVAYRSMEGYDYEYDSDGRRHKVPVAQSYHNLRYSKKGRFQVNISQNLGDYGSLYLSGSQQNYWNTADTNTWYQLGYASGWQGISYSLSWSWSESVGSSGADRILAFNMSVPFSVLTGRRYARDTILDRTYATFNANRNRDGDNSWQTGVGGTLLEGRNLSYSVTQGRSSSNGYSGSASASWQATYGTLGVGYNYDRDQHDYNWQLSGGVVGHADGITFSQPLGDTNVLIKAPGAKGVRIENQTGVKTDWRGYAVMPYATVYRYNRVALDTNTMDNHTDVENNVSSVVPTEGALVRAAFDTRIGVRAIITARLGGRPLPFGAIVRETASGITSMVGDDGQIYLSGLPLKGELFIQWGEGKNARCIAPYALAEDSLKQAITIASATCIRPAS

fimD

Major fimbrium tip subunit FimD

670 amino acids

Probably a component of the fimbrium tip (PubMed:17526848, PubMed:19506009). These long, filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome (PubMed:17526848). They play an important role in invasion of periodontal tissues and are major virulence factors. FimC, FimD and FimE contribute to interaction with host CXCR4 and thereby down-regulate the TLR2-mediated host immune response (PubMed:17675496, PubMed:19506009).

Belongs to the FimD family.

75.848 kDa

MRTNRILNIICPPILFLLVGFLFGCVREDIESDMNETSSLFLQVQPYNQRSEEGGVAAYDENTIERLTLVFYKNGTKVWQAEPVETSPSSNSYYVPVPESMYGQFNGNNSFKIYLVANVNFSGSFEPNASETSFLKTLVPNSILLQNDGKPEDKFAMIGSVEKQINMATSEGKQLGSIELKRVAAKLRLKKPVLNISDYELVGDPKAKFRNCMPKGFLSVEEKPEGVGYEAIDYRPMTEANSSVHFYSYYNEWALNNEGRPEFVMMLKLKKTGTDDNTAKPYYYRIPVDGSDKKIRSNHLYDMAVTIEVLGSLNEEDPVTINGSLSVIEWTSHSDDQTLPDVQYLEVIPQETVMNMTTEIELDYFSSHSLLPPADVKATCTYVNSNGQQITDTYTGANVPTVTIDANTKKIKVRSILPINNIPKDISFTIKNSIGFEKKIKIRQNPSQFIINTFGTKSSWQPEGNLAPNLNNKAIYQIVVLSPPADGNMIIGFPPTKEVGFYKKSGSSYTLKHTDRITEQDEQTANMVSPSFELASQLGATLVQDHWEYYTLNPLRLIYHSNQQNRYALMTCAFYWEERKKADGTIERLDDWRLPTRAEIQLVDKLQREQAGVVRDIMTGRYYWSGLPDKAIKILLPTASGNATEQRAHVRCVRDVKNDRFVKSAKRLKK

fimD

Major fimbrium tip subunit FimD

670 amino acids

Probably a component of the fimbrium tip. These long, filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome. They play an important role in invasion of periodontal tissues and are major virulence factors. FimC, FimD and FimE contribute to interaction with host CXCR4 and thereby down-regulate the TLR2-mediated host immune response.

Belongs to the FimD family.

75.848 kDa

MRTNRILNIICPPILFLLVGFLFGCVREDIESDMNETSSLFLQVQPYNQRSEEGGVAAYDENTIERLTLVFYKNGTKVWQAEPVETSPSSNSYYVPVPESMYGQFNGNNSFKIYLVANVNFSGSFEPNASETSFLKTLVPNSILLQNDGKPEDKFAMIGSVEKQINMATSEGKQLGSIELKRVAAKLRLKKPVLNISDYELVGDPKAKFRNCMPKGFLSVEEKPEGVGYEAIDYRPMTEANSSVHFYSYYNEWALNNEGRPEFVMMLKLKKTGTDDNTAKPYYYRIPVDGSDKKIRSNHLYDMAVTIEVLGSLNEEDPVTINGSLSVIEWTSHSDDQTLPDVQYLEVIPQETVMNMTTEIELDYFSSHSLLPPADVKATCTYVNSNGQQITDTYTGANVPTVTIDANTKKIKVRSILPINNIPKDISFTIKNSIGFEKKIKIRQNPSQFIINTFGTKSSWQPEGNLAPNLNNKAIYQIVVLSPPADGNMIIGFPPTKEVGFYKKSGSSYTLKHTDRITEQDEQTANMVSPSFELASQLGATLVQDHWEYYTLNPLRLIYHSNQQNRYALMTCAFYWEERKKADGTIERLDDWRLPTRAEIQLVDKLQREQAGVVRDIMTGRYYWSGLPDKAIKILLPTASGNATEQRAHVRCVRDVKNDRFVKSAKRLKK

fimD

Putative fimbrial assembly protein FimD, serogroup D

394 amino acids

45.147 kDa

MFKKFLWRDCVFIIVLITAIALPAYIHTNYPQAFSRFFYPVEAWFTKRDLRCSKNAPHFLRQLLIEMIDEQKSLNNQVAFWHNGQLFHCESGWEDGFRGEKPMRVNSRFRYASVTKVLTSALVLHAINEQKLSLDSKIIELLELPAPKDPRVAAITIKMLLEHSAGFDRLKTYMPMLTMDVKPWCPTNLAQLSKTKLDFDPETQFQYSNVGYCLLGAAIEKAYGRTFQSVAEDYFQLKKYGIAFVGDRFLPDEIQYDYRFESFYSEFYLKHFDFKDSLYAVGGLSGSAADIVQLLAALPKEAPLTIFSHNHTPCSINMLDACYGYALQPYQASGQSYTLWGKSGFFPGVNTDVFLDEQGNILATLRAASAKKTADTLLLRQYAYSLMNEYVNQK

fimD

Probable fimbrial assembly protein FimD, serogroup H1

394 amino acids

45.106 kDa

MFKKFLWRDCVFIIVLITTIALPAYIHTNYPQAFSRFFYPVEAWFTKRDLRCSKNAPHFLRQLLIEMIDEQKSLNNQVAFWHNGQLFHCESGWEDGFRGEKPMRVNSRFRYASVTKVLTSALVLHAINEQKLSLDSKIIELLELPAPKDPRVAAITIKMLLEHSAGFDRLKTYTPMLTMDVKPWCPTNLAQLSETKLDFDPETQFQYSNVGYCLLGAAIEKAYGRSFQSVAEDYFQLKKYGVSYVGDGFLPDEIQYDYRFEPFYAESYSKHFDFKDSLYAVGGLSGSAADIVQLLAALPKETPLTIFSHNHAPCSINILDACYGYALQPYQASRQSYTLWGKSGFFPGVNTDVFLDEQGNILATFRAASTKKTADTLLLRQYAYSLMNEYVNQK