FILIP1L

Filamin A-interacting protein 1-like

1135 amino acids

Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.

Belongs to the FILIP1 family.

130.382 kDa

MRSRGSDTEGSAQKKFPRHTKGHSFQGPKNMKHRQQDKDSPSESDVILPCPKAEKPHSGNGHQAEDLSRDDLLFLLSILEGELQARDEVIGILKAEKMDLALLEAQYGFVTPKKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNGRRISDPQVFSKEVQTEAVDNEPPDYKSLIPLERAVINGQLYEESENQDEDPNDEGSVLSFKCSQSTPCPVNRKLWIPWMKSKEGHLQNGKMQTKPNANFVQPGDLVLSHTPGQPLHIKVTPDHVQNTATLEITSPTTESPHSYTSTAVIPNCGTPKQRITILQNASITPVKSKTSTEDLMNLEQGMSPITMATFARAQTPESCGSLTPERTMSPIQVLAVTGSASSPEQGRSPEPTEISAKHAIFRVSPDRQSSWQFQRSNSNSSSVITTEDNKIHIHLGSPYMQAVASPVRPASPSAPLQDNRTQGLINGALNKTTNKVTSSITITPTATPLPRQSQITVEPLLLPH

Filip1l

Filamin A-interacting protein 1-like

1131 amino acids

Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature (By similarity).

Belongs to the FILIP1 family.

129.772 kDa

MRSRSSNAEGSAPKQIPRHSKFQDSIQDMKHRTHKKDPSCESEGVLPRPVSEKSHTGKGHHTEDLSRDDLLFLLSILEGELQARDEVIGILRAEKIDLALLEAQYGFVTPKKVLEALQRDAFQAKSAPWQEDIYEKPMNELDKVVEKHKESHRRILEQLLMVERSHRQTIMEMEEEKRKHKEYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQEKEKRIKTLKEELTKLKSFALMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNGRRISDPQVFSKEVQTEAADSEPPDYKSLIPLERAVINGQFYEENEDQDDDPNEEESVLSFRCSQSSSLPMNRKLWIPWMKSKEGHPQNGKIQTKSNGNFVQPGDLVLSHTPGQPLHIKVTPDHIQNTATLEITSPTTESPHSYTSTAVIPNCGTPKQRITILQNASITPIKSKSSTESLMNLEQSMSPVTMATFARAQTPESCGSVTPERTMSPIQVLAMTGSPSSPEQGCSPEPIEISAKHAIFRVSPDRQSSWQFQRSNSNSSSVITTEDNKIHIHLGSPYMQAVAGPMRPASPSAPLQDNRTQGLTNGALNKTTNKVTSSITITPTATPLPRQSQITVSNIYN

filip1l

Filamin A-interacting protein 1-like

1129 amino acids

Belongs to the FILIP1 family.

129.74 kDa

MRSRSSSLEDTGKAGLSSPRGGTRRDQANHSSRRPQEATPTIHRNHRQREHKPKPKSRDLTRDDLLFLLSMLEGELQARDEVITVLKAEKIDLALLEAKYGFVTPTAVLKSLQRDGLQQSSGWQEDIYEKPIAELDRLVEKQRETHRRMLEQLLLVERAHKHTLHRLEDEKKNHRDFMKKSDDFTSLLEHDRERLKQLIDQEKTYQERKEEESNKQVTNLKDELTKLKSFALLVVDEQQRLTEQLSQQITKVQELQNSAGQAQEELNSAQTRLQDEENKVLRLEEELRKQTCHFHQEQDAMTAKLTNEDAQNRQLRQKLSSLSRQLDELEEINKTLHRAEEELQELRDKISRGECGNSSLVSEVEELRKRVLEMEGKDEELIKMEDMCRELNRKLEKEAKQSCSLKAEVDKLNHRIMELEKLEDAFRKSKQECNSLKSNLEKERTMTKHMSNELDVLRVRIKELETTEVHLEKTELTLKEDLTKLKTLTVMLVDERKAMAEKLKMMEDKVQNSTGKLQAEQDKVNTVTEKLIEESKKTLRSKAELEEKMCVATRERDELKAKLKTEEEKSSDLQSKVSMMKKRLQSLETVERELLRNKSKEEHTKSPGPYRYQQEDNKVKDLTQEVERLRRKLKEMKVVEGDLLKTEDEFESLEKRYSNEQERAKALMEELETSRKELSKYQLAEKEESNQEQILYKRLKEEEAKSSHLTREVEALKEKIHEYMGTEESICRLKTDHTTLQRKLTQQEVRNKELAREMETLTRELERYRRFSKSLRPGMNGRRFSDLHVSTKEVQTDPTDSLSPNYKNLAPLERALVNGKLYVESDPEDEANYNEIHLTKCSPSLMNSVNNLNNNMRRVRGPFLKPRENHHAVNNKRQNGNHVQQGDVVLTHSPGQPVHIKVTPDHGHNTATLEITSPTSENAPSYTSTAVIPTTGAPPKQRITILQNSISPSGKPKGSPPPPESPCTPDRSLSPLTMTAYSQTLTSESCGPLTPDRALSPIQIVSVTTGSPDRSEPAELLGGQTVLRVSPERQNSWQIQRSNSTGPNVITTDDNKIHIHLGSPYIQAVTPSAKPIGPYYSLGPEPRVPVLNNGTPAKGNNKITSSIVIKPTSGPISRPSQITVSNLCD