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fhbA

Gene
fhbA
Protein
Flavohemoprotein A
Organism
Dictyostelium discoideum
Length
397 amino acids
Function
In the presence of oxygen and NADH, it has NADH oxidase activity, which leads to the generation of superoxide and H(2)O(2). Under anaerobic conditions, it also exhibits nitric oxide reductase and FAD reductase activities. However, all these reactions are much lower than NOD activity (By similarity).
Similarity
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Mass
43.925 kDa
Sequence
MSLSQQSISIIKATVPVLQVHGVNITTTFYRNMFKANPQLLNIFNHSNQREGKQQNALANTVLQAAIHIDKLNELNLAPIVHKHVALGVLPEHYPIVGTNLLGAIKEVLQDAATDEILGAWGEAYGVIAQAFIDAEAALYKVTEEQIGGWRDTREFIVDRKVEESSNIISFYFKPADGKPIATYIPGQYITIKVPLTLENGEQRTHIRHYSLSDTPSEQYYRISVKKEDALKKSDPNGVVSNHLHANVKVGDKVLLSPPAGDYVVDQLSSNPILLVSGGVGITPLLSMAKATLAKQPEREVTFVHSSKNKQYQPFANELSQLEKSNKVKVSTVHSETDGQITKDKLEKFINPSQIKDTKVFICGPVSFMSAINKQLIELGYPKENISYEIFGPLTNV