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fgaDH

Gene
fgaDH
Protein
Chanoclavine-I dehydrogenase
Organism
Neosartorya fumigata
Length
261 amino acids
Function
Oxidoreductase involved in the biosynthesis of ergot alkaloid biosynthesis. Catalyzes the oxidation of chanoclavine-I in the presence of NAD(+) resulting in the formation of chanoclavine-I aldehyde. Ergot alkaloids, which are produced by endophyte fungi, can enhance plant host fitness, but also cause livestock toxicosis to host plants.
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Mass
27.796 kDa
Sequence
MASVESRIIAITGGASGIGAATCRLLAERGAAVLCVCDISPKNFDDLKISIKKINPSTKVHCATVDVTSSVEVRQWIEGIISDFGDLHGAVNAAGIAQGAGMRNTPTIAEEVDEEWTRIMNTNLNGVFYCTREEVRAMKGLPATDRSIVNVGSIASVSHMPDVYAYGTSKGACAYFTTCVAADAFPLGIRINNVSPGVTNTPMLPQFAPMAKTFEEIEESYKKEGLSLIEAEDVARTIVWLLSEDSRPVFGANINVGACMP