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fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Helicobacter pylori (strain J99 / ATCC 700824)
Length
275 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
30.026 kDa
Sequence
MGFLKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSPYVYELDVSKEEHFKSLYNNIKQDLGSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAMEISVYSLIELTNTLKPLLNNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLGKHNIRVNALSAGPIRTLASSGIADFRMILKWNEINAPLRKNVSLEEVGNAGMYLLSSLSNGVSGEVHFVDAGYHVMGMGAVEEKDNKATLLWDLHKEQ
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Helicobacter pylori (strain ATCC 700392 / 26695)
Length
275 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
29.981 kDa
Sequence
MGFLKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRPIAQELNSPYVYELDVSKEEHFKSLYNSVKKDLGSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAMEISVYSLIELTNTLKPLLNNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLGKHHIRVNALSAGPIRTLASSGIADFRMILKWNEINAPLRKNVSLEEVGNAGMYLLSSLSSGVSGEVHFVDAGYHVMGMGAVEEKDNKATLLWDLHKEQ
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Aquifex aeolicus (strain VF5)
Length
270 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
29.725 kDa
Sequence
MGLLEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSDLVVKCDVSLDEDIKNLKKFLEENWGSLDIIVHSIAYAPKEEFKGGVIDTSREGFKIAMDISVYSLIALTRELLPLMEGRNGAIVTLSYYGAEKVVPHYNVMGIAKAALESTVRYLAYDIAKHGHRINAISAGPVKTLAAYSITGFHLLMEHTTKVNPFGKPITIEDVGDTAVFLCSDWARAITGEVVHVDNGYHIMGVFGREEEIKKEVYGD
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Length
265 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.006 kDa
Sequence
MGFLTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPELCFPCDVADDSQIEAVFAALGKHWDGLDIIVHSVGFAPGDQLDGDFTAVTTREGFRIAHDISAYSFIALAKAGREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAGSLGAEGTRVNAVSAGPIRTLAASGIKSFRKMLAANERQTPLRRNVTIEEVGNAGAFLCSDLASGISGEILYVDGGFNTTAMGPLDDD
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Rickettsia bellii (strain RML369-C)
Length
262 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.415 kDa
Sequence
MTTGLLQGKRGIITGIANNMSISWAIAQLARKHGAELCFTYQSEILEKRVKPLAEEVGCNFVSELDVTNPESITNLFAEVKEKWGTFDFLLHGMAFSDRNELKGRYIDTSLGNFNNSLHISCYSLVELAREAEKLMNDGGSIVTLSYYGAEKVIPNYNVMGVAKAALEASVRYLANDMGENNIRVNAISAGPIKTLSGSVIGDFNSMLRSHAATAPLKRNTLQQDVAGAAVYLFSQLASGVTGEIHYVDCGYNVMGSNKIVG
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
262 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.761 kDa
Sequence
MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSSIVLPCDVAEDASIDAMFAELGNVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKVAHDISSYSFVAMAKACRTMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Shigella flexneri
Length
262 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.864 kDa
Sequence
MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Rickettsia bellii (strain RML369-C)
Length
262 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.415 kDa
Sequence
MTTGLLQGKRGIITGIANNMSISWAIAQLARKHGAELCFTYQSEILEKRVKPLAEEVGCNFVSELDVTNPESITNLFAEVKEKWGTFDFLLHGMAFSDRNELKGRYIDTSLGNFNNSLHISCYSLVELAREAEKLMNDGGSIVTLSYYGAEKVIPNYNVMGVAKAALEASVRYLANDMGENNIRVNAISAGPIKTLSGSVIGDFNSMLRSHAATAPLKRNTLQQDVAGAAVYLFSQLASGVTGEIHYVDCGYNVMGSNKIVG
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Length
262 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.761 kDa
Sequence
MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSSIVLPCDVAEDASIDAMFAELGNVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKVAHDISSYSFVAMAKACRTMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Shigella flexneri
Length
262 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.864 kDa
Sequence
MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Escherichia coli O157:H7
Length
262 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.864 kDa
Sequence
MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Escherichia coli (strain K12)
Length
262 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.864 kDa
Sequence
MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Length
262 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.119 kDa
Sequence
MGFLTGKRILVTGLASNRSIAYGIAKSMKEQGAELAFTYLNDKLQPRVEEFAKEFGSDIVLPLDVATDESIQNCFAELSKRWDKFDGFIHAIAFAPGDQLDGDYVNAATREGYRIAHDISAYSFVAMAQAARPYLNPNAALLTLSYLGAERAIPNYNVMCLAKASLEAATRVMAADLGKEGIRVNAISAGPIRTLAASGIKNFKKMLSTFEKTAALRRTVTIEDVGNSAAFLCSDLASGITGEIVHVDAGFSITAMGELGEE
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Rickettsia prowazekii (strain Madrid E)
Length
261 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.538 kDa
Sequence
MTTGLLQGKKGLITGIANNMSISWAIAQLAKKHGAELWFTYQSEVLEKRVKPLAEEIGCNFISELDVTNQKSISNLFNDIKEKWNSFDFLLHGMAFANKNELKGRYVETSLENFHNSLHISCYSLLELSRSAETLMHNGGSIVTLTYYGAEKVIPNYNIMGVAKAALEASVKYLANDMGENNIRVNAISAGPIKTLASSAISDFSTMLKSHAATAPLKRNITQEDVGGAAVYLFSELSKGVTGEIHYVDCGYNIIGSSKLL
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Length
261 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.713 kDa
Sequence
MTTRLLQGKKGLITGIANNMSISWAIAQLAKKHGAELWFTYQSEALEKRVKPLAEEIGCNFISELDVTDQKSISNLFNDIKEKWNSFDFLLHGMAFANKNELKGRYVDTSLENFYNSLHISCYSLLELSRSAETLMHDGGSILTLTYYGAEKVIPNYNIMGVAKAALEASVKYLANDMGENNIRVNAISAGPIKTLASSAISDFSTMLKFHASTAPLKRNITQEDVGGAAVYLFSELSKGVTGEIHYVDCGYNIIGSSKLL
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Rickettsia prowazekii (strain Madrid E)
Length
261 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.538 kDa
Sequence
MTTGLLQGKKGLITGIANNMSISWAIAQLAKKHGAELWFTYQSEVLEKRVKPLAEEIGCNFISELDVTNQKSISNLFNDIKEKWNSFDFLLHGMAFANKNELKGRYVETSLENFHNSLHISCYSLLELSRSAETLMHNGGSIVTLTYYGAEKVIPNYNIMGVAKAALEASVKYLANDMGENNIRVNAISAGPIKTLASSAISDFSTMLKSHAATAPLKRNITQEDVGGAAVYLFSELSKGVTGEIHYVDCGYNIIGSSKLL
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Rickettsia typhi (strain ATCC VR-144 / Wilmington)
Length
261 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.713 kDa
Sequence
MTTRLLQGKKGLITGIANNMSISWAIAQLAKKHGAELWFTYQSEALEKRVKPLAEEIGCNFISELDVTDQKSISNLFNDIKEKWNSFDFLLHGMAFANKNELKGRYVDTSLENFYNSLHISCYSLLELSRSAETLMHDGGSILTLTYYGAEKVIPNYNIMGVAKAALEASVKYLANDMGENNIRVNAISAGPIKTLASSAISDFSTMLKFHASTAPLKRNITQEDVGGAAVYLFSELSKGVTGEIHYVDCGYNIIGSSKLL
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Neisseria meningitidis serogroup B (strain MC58)
Length
261 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.691 kDa
Sequence
MGFLQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSELVFRCDVASDDEINQVFADLGKHWDGLDGLVHSIGFAPKEALSGDFLDSISREAFNTAHEISAYSLPALAKAARPMMRGRNSAIVALSYLGAVRAIPNYNVMGMAKASLEAGIRFTAACLGKEGIRCNGISAGPIKTLAASGIADFGKLLGHVAAHNPLRRNVTIEEVGNTAAFLLSDLSSGITGEITYVDGGYSINALSTEG
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Length
260 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.211 kDa
Sequence
MTTGLLQGKKGLITGIANNMSISWAIAQLAKKHGAELWFTYQSGVLEKRVKPLAKEIGCNFVSELDVTKPKSISNLFDDIKEKWGSFDFLLHGMAFADKNELKGRYVDTSLENFHNSLHISCYSLLELSRSAEALMHNGGSIVTLTYYGAEKVIPNYNVMGVAKAALEASIKYLANDMGENNIRVNAISAGPIKTLASSAIGDFSTMLKSHAATAPLKRNTTQEDVGGAAVYLFSELSKGVTGEIHYVDCGYNIMGSTKL
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)
Length
260 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.254 kDa
Sequence
MTTGLLQGKKGLITGIANNMSISWAIAQLAKKHGAELWFTYQSEVLEKRVKPLAEEIGCNFVSELDVTNPKSISNLFDDIKEKWGSFDFLLHGMAFADKNELKGRYVDTSLENFHNSLHISCYSLLELSRSAEALMHDGGSIVTLTYYGAEKVIPNYNVMGISKAALEASVKYLATDLGENNIRVNAISAGPIKTLASSAIGDFSTMLKSHAATAPLKRNTTQEDVGGAAVYLFSNLSKGVTGEIHYVDCGYNIMGSNKL
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Rickettsia conorii (strain ATCC VR-613 / Malish 7)
Length
260 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.211 kDa
Sequence
MTTGLLQGKKGLITGIANNMSISWAIAQLAKKHGAELWFTYQSGVLEKRVKPLAKEIGCNFVSELDVTKPKSISNLFDDIKEKWGSFDFLLHGMAFADKNELKGRYVDTSLENFHNSLHISCYSLLELSRSAEALMHNGGSIVTLTYYGAEKVIPNYNVMGVAKAALEASIKYLANDMGENNIRVNAISAGPIKTLASSAIGDFSTMLKSHAATAPLKRNTTQEDVGGAAVYLFSELSKGVTGEIHYVDCGYNIMGSTKL
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)
Length
260 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.254 kDa
Sequence
MTTGLLQGKKGLITGIANNMSISWAIAQLAKKHGAELWFTYQSEVLEKRVKPLAEEIGCNFVSELDVTNPKSISNLFDDIKEKWGSFDFLLHGMAFADKNELKGRYVDTSLENFHNSLHISCYSLLELSRSAEALMHDGGSIVTLTYYGAEKVIPNYNVMGISKAALEASVKYLATDLGENNIRVNAISAGPIKTLASSAIGDFSTMLKSHAATAPLKRNTTQEDVGGAAVYLFSNLSKGVTGEIHYVDCGYNIMGSNKL
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)
Length
260 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.779 kDa
Sequence
MGFLKGKKFLIIGISSVRSIAFGIAKSLYNQKAELGFVCQNEKIRKKIKKLVEPMKSCIVLCCDVSNDKNIKKLFIDLGQVWKKFDGLVHAIAYCPKQYFNGDFIDNITREGFNISHEISSYSFIGLVKACRTMLNNFSSLLTLSYLGSQRVVPNYNVMGLAKASLEASVRYMASSLGKENIRVNAISSSPIKTISSYKITNFNKIRNCSYASSFLKNSVTSENIGNVASFLLSDLSLGITGSVIYVDNGFNVSSMNNIQ
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)
Length
260 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
29.268 kDa
Sequence
MGILKGKKILITGILNEKSIAFGIAKSMYKQEAELIFVCQNKKIINKIKYLIKSINYNTIFFCDVSHDENIKELFFNIKKVWNNFDGLVHSIAYCPKKQMHEDFVESSSRKSFNICHEISSYSFLSMARECKNMLNKFSSLVTLSYLGSQKIVSNYNMMGLAKSSLEANVRYMANSLGKNNIRVNAISSGPIKTTSSYQIKNFNKIQKIHKLFSLTKNHVSSEEIGNVAAFLCSDLSIGITGSIINVDHGFNLNGINSII
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)
Length
260 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.5 kDa
Sequence
MGFLEEKKILVTGISNKYSIAFGIAKALHKQNATLAFSYHTDRLKNKVYELAKELGVKIVIPCDVSDDNSIKRLFFNISKKWITFDGFIHSIAFAPKNQLSGDYVSSITRLDFSNVLDVSSYSFVGMAKACRSILKKGSSLLTLSYIGSKKVVPNYNVMGIAKASLESNVRYMASCMGLNGIRVNAISSSPIKTLSSYHIKNFKKILNHTTSRSLNNNLTTVEDVGNTAAFLCSDLSKGITGQIIYVDGGFNITAMSNSE
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
258 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.626 kDa
Sequence
MLDLSGKHAFVTGIANNRSIAWGIAQQLHQAGAEIGVSYLPDEKGRFEKKVRELTEPLHPTLVLPGDVQDDAQVDALFHSVKEKWGKLDILIHCLAFADKSGLTGNYTDIPKEAFSQAMEISTYSLGRLARGAKPLMTNGGSIITLTYFGGVKVIPNYNLMGVAKAGLEMTVRYLAAELGPQNIRVNGISAGPIRTLASSAVGGILDMIHHVEEVAPLKRTVTQTEVGNTAAFLASDLSSGITGQIIYVDSGYEIMGM
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
258 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.626 kDa
Sequence
MLDLSGKHAFVTGIANNRSIAWGIAQQLHQAGAEIGVSYLPDEKGRFEKKVRELTEPLHPTLVLPGDVQDDAQVDALFHSVKEKWGKLDILIHCLAFADKSGLTGNYTDIPKEAFSQAMEISTYSLGRLARGAKPLMTNGGSIITLTYFGGVKVIPNYNLMGVAKAGLEMTVRYLAAELGPQNIRVNGISAGPIRTLASSAVGGILDMIHHVEEVAPLKRTVTQTEVGNTAAFLASDLSSGITGQIIYVDSGYEIMGM
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Bacillus subtilis (strain 168)
Length
258 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism.
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.874 kDa
Sequence
MNFSLEGRNIVVMGVANKRSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTNDAEIETCFASIKEQVGVIHGIAHCIAFANKEELVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRTLSAKGISDFNSILKDIEERAPLRRTTTPEEVGDTAAFLFSDMSRGITGENLHVDSGFHITAR
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Length
258 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.421 kDa
Sequence
MLNLTGKNALVTGIANNRSIAWGIAQQLHAAGANLGITYLPDERGKFEKKVSELVEPLNPSLFLPCNVQNDEQIQSTFDTIRDKWGRLDILIHCLAFANRDDLTGDFSQTSRAGFATALDISTFSLVQLSGAAKPLMTEGGSIITLSYLGGVRAVPNYNVMGVAKAGLEASVRYLASELGSQNIRVNAISAGPIRTLASSAVGGILDMIHHVEQVAPLRRTVTQLEVGNTAAFLASDLASGITGQVLYVDAGYEIMGM
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI
Organism
Staphylococcus aureus (strain NCTC 8325)
Length
256 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It has a preference for a long chain (C12) substrate compared to the shorter (C4) acyl group. Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.022 kDa
Sequence
MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISASPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK
Protein
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI
Organism
Staphylococcus aureus (strain MRSA252)
Length
256 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.992 kDa
Sequence
MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK
Protein
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI
Organism
Staphylococcus aureus (strain NCTC 8325)
Length
256 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). It has a preference for a long chain (C12) substrate compared to the shorter (C4) acyl group. Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
28.022 kDa
Sequence
MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISASPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK
Protein
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI
Organism
Staphylococcus aureus (strain MRSA252)
Length
256 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.992 kDa
Sequence
MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK
Protein
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NRRL B-3711)
Length
256 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
27.74 kDa
Sequence
MELLQGKTFVVMGVANQRSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEGQESLVLPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFANRDDLKGEFVDTSRDGFLLAQNISAFSLTAVAREAKKVMTEGGNILTLTYLGGERVVKNYNVMGVAKASLEASVKYLANDLGQHGIRVNAISAGPIRTLSAKGVGDFNSILREIEERAPLRRTTTQEEVGDTAVFLFSDLARGVTGENIHVDSGYHILG
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Enterococcus faecalis (strain ATCC 700802 / V583)
Length
250 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
26.767 kDa
Sequence
MFLQNKNVVVMGVANKKSIAWGCAKALKDQGANVIYTYQNERMKKQVVKLADENDLLVECDVASDASIQAAFETIKNEVGTIDGLVHAIAFAKKEELSGNVSDITRDGFLLAQDISSYSLLAVTHYAKPLLNPGSGIVTLTYLGSERAIPNYNMMGIAKASLETAVKYLAFELAADKIRVNGISAGAIKTLAVTGVKDYDQLISISNERTPDKTGVTIEEVGNTCAFLVSDLASGVVGDIIYVDKGVHLT
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI: fabI

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Rhizobium meliloti
Length
55 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
5.905 kDa
Fragment
single
Sequence
MSIPTVKAKLLQGRKGLIVGIANDRSIAWGRARAFRALGAEIAVTYLNDKALPLV

Gene
fabI
Protein
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Organism
Rhizobium meliloti
Length
55 amino acids
Function
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
Similarity
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Mass
5.905 kDa
Fragment
single
Sequence
MSIPTVKAKLLQGRKGLIVGIANDRSIAWGRARAFRALGAEIAVTYLNDKALPLV