esco2

N-acetyltransferase ESCO2

609 amino acids

Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development (PubMed:15256591).

Belongs to the acetyltransferase family. ECO subfamily.

68.36 kDa

MLSRKRKHGSPDAESNPSKKQITSLRSSPRRTTRQKENIPISLNSPQKIPSTPKKTQRAFLLESPPKRVSPRKAVLGAGTFYSKQKPLYLTPLERKVLKEAKSPPSVTNKEPSRPPLTAANQVVKPAKKVQKKPRASAPQSNLKGYFTAKPKATKSSSDKQTDQVLKSTMAPISFSSMKSKGKPKLVVGAAFFNTGKKPTSMYKKSAQNTKPKPTYEKPSIRKPVREKELVTAPGQRSPVRRAVFLKKQPEVEVSHDKRESTQAPMSPQVLADVHGITKELRVVLRRSVSPETGSQDAPSEADSVFDVSDLLLPDHDSSHDEEESSVYPIFGTKRPQKKGKLSPPLNSSTPSALTATPALKAKERSMLRREMKKQTDNQLIIDAGQKQFGATTCASCGMLYSTDSPEDNFQHTQFHQRFLDTIKFVGWKKERVVAEFWDGKIILVLPDDPKYATRKAEDVRRIADSELGFQQITLSSPSSAKTYLFINTDRMVVGCLVAENIRQAYRVLEQQEKQKDMSKEDFMEHHRTWCCSTVPEKALCGVSRIWVFSLMRRKSVATRLLDTARNTFMYGSHLTKEEIAFSDPTPQGKLFATKYCQTPTFLVYNFIS

esco2

N-acetyltransferase ESCO2

609 amino acids

Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together (By similarity). Essential for early development (PubMed:15256591).

Belongs to the acetyltransferase family. ECO subfamily.

68.36 kDa

MLSRKRKHGSPDAESNPSKKQITSLRSSPRRTTRQKENIPISLNSPQKIPSTPKKTQRAFLLESPPKRVSPRKAVLGAGTFYSKQKPLYLTPLERKVLKEAKSPPSVTNKEPSRPPLTAANQVVKPAKKVQKKPRASAPQSNLKGYFTAKPKATKSSSDKQTDQVLKSTMAPISFSSMKSKGKPKLVVGAAFFNTGKKPTSMYKKSAQNTKPKPTYEKPSIRKPVREKELVTAPGQRSPVRRAVFLKKQPEVEVSHDKRESTQAPMSPQVLADVHGITKELRVVLRRSVSPETGSQDAPSEADSVFDVSDLLLPDHDSSHDEEESSVYPIFGTKRPQKKGKLSPPLNSSTPSALTATPALKAKERSMLRREMKKQTDNQLIIDAGQKQFGATTCASCGMLYSTDSPEDNFQHTQFHQRFLDTIKFVGWKKERVVAEFWDGKIILVLPDDPKYATRKAEDVRRIADSELGFQQITLSSPSSAKTYLFINTDRMVVGCLVAENIRQAYRVLEQQEKQKDMSKEDFMEHHRTWCCSTVPEKALCGVSRIWVFSLMRRKSVATRLLDTARNTFMYGSHLTKEEIAFSDPTPQGKLFATKYCQTPTFLVYNFIS

ESCO2

N-acetyltransferase ESCO2

601 amino acids

Acetyltransferase required for the establishment of sister chromatid cohesion (PubMed:15821733, PubMed:15958495). Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3 (PubMed:21111234).

Belongs to the acetyltransferase family. ECO subfamily.

68.307 kDa

MAALTPRKRKQDSLKCDSLLHFTENLFPSPNKKHCFYQNSDKNEENLHCSQQEHFVLSALKTTEINRLPSANQGSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFPIVTEKMQGKPVCSKKNNKKPQKSLTAKYQPKYRHIKPVSRNSRNSKQNRVIYKPIVEKENNCHSAENNSNAPRVLSQKIKPQVTLQGGAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEVIEDSDVETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDRVSSKEHKVDKNEAFSSEDSLGENKTISPKSTVYPIFSASSVNSKRSLGEEQFSVGSVNFMKQTNIQKNTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHRFLEGIKYVGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPKCPNKIKTFLFISDEKRVVGCLIAEPIKQAFRVLSEPIGPESPSSTECPRAWQCSDVPEPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATKYCNTPNFLVYNFNS

ESCO2

N-acetyltransferase ESCO2

601 amino acids

Acetyltransferase required for the establishment of sister chromatid cohesion (PubMed:15821733, PubMed:15958495). Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3 (PubMed:21111234).

Belongs to the acetyltransferase family. ECO subfamily.

68.307 kDa

MAALTPRKRKQDSLKCDSLLHFTENLFPSPNKKHCFYQNSDKNEENLHCSQQEHFVLSALKTTEINRLPSANQGSPFKSALSTVSFYNQNKWYLNPLERKLIKESRSTCLKTNDEDKSFPIVTEKMQGKPVCSKKNNKKPQKSLTAKYQPKYRHIKPVSRNSRNSKQNRVIYKPIVEKENNCHSAENNSNAPRVLSQKIKPQVTLQGGAAFFVRKKSSLRKSSLENEPSLGRTQKSKSEVIEDSDVETVSEKKTFATRQVPKCLVLEEKLKIGLLSASSKNKEKLIKDSSDDRVSSKEHKVDKNEAFSSEDSLGENKTISPKSTVYPIFSASSVNSKRSLGEEQFSVGSVNFMKQTNIQKNTNTRDTSKKTKDQLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHRFLEGIKYVGWKKERVVAEFWDGKIVLVLPHDPSFAIKKVEDVQELVDNELGFQQVVPKCPNKIKTFLFISDEKRVVGCLIAEPIKQAFRVLSEPIGPESPSSTECPRAWQCSDVPEPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDGKLFATKYCNTPNFLVYNFNS

Esco2

N-acetyltransferase ESCO2

592 amino acids

Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3.

Belongs to the acetyltransferase family. ECO subfamily.

67.273 kDa

MMATCTPRKRKRYTLNADNDDSLLTDISSSKLRCAENLFPSPNKKHNYQSSVQKEDKSCSHQLHFPSSPLKTTENSRFSFANHSSLFKPAMSTVSFYSKEKYYLNPLERKLIRECRSICLATESGDKPIPSVTENIQRKPVCTKKNKKKQKSLTAKYQPNYKHIKSKSRNLKNSKPNQVTYKPVVDQENSCFPAKNYPNSPPRVLSQKIKPQVTLQGGAAFFVRKRNSLKKLPLEDKPLLLQKNLPEVPEGAPEAKQIPKSLLVDEKSSVKVQNARSKNEEKLRKNPSGAVVSSKECNLDKHDFPSENSLDENKTISPESVYPIFNVSSVNTKRPEEQSSVGSTACTNFLKQTNVPKNINSRDTNKGGKDQLVIDAGQKHFGTTVCKSCGMIYTASNPEDEIQHLQHHHRFLEGIKFVGWKRERVVAEFWDGKIVLVLPRDPSYAIKKVEDVQELVDLELGFQQTVPVCPDKTKTFLFIDEKRVVGCLIAEPIKQAFRVLSEPSASKECSRAWRCSDVPEPAICGISRIWVFRLKRRKRIARRLVDTVRNCFMFGCFLSTNEIAFSDPTPDGKLFATKYCNTPNFLVYNFHN