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epl-1

Gene
epl-1
Protein
Enhancer of polycomb-like protein 1
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
589 amino acids
Function
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity).
Similarity
Belongs to the enhancer of polycomb family.
Mass
67.297 kDa
Sequence
MATRKVRYKKLSVKTQLAVLREDQIEASEYESLTSENQIATGVEQAEENEYHLQAVLKGAGVAADQEIPVPPPQQSELDYDQFYPQKVAKTSTYIRFSQTVEECISCLYDMTEDDETFLKSYNMKLTPSARLSEDDFERIMDVYEDMAANITPFSAIDQTVPSYQEMLRGLEPLDSTKVMVHAKQIYEYWKSRREISKNRPLNPTLKFETHAESDELDPYVCFRRREIRQTRKTRARDVQSADKLKRLRKELEEGRQLILAAHNRELLKADMLKVERAIFDQRAIIKEQKLRLGIRTGDEDLVNQKPQKRKAPEAPSAQRPPPPPQIRMPVRPDGRPAESDLVQLSDRLAEKNAELIIEIEKKIQNHIDWNKNYVDLTGKPLSPVQGPRQDLGFRPAKTQYLMTPPASASSGSMDEPTPMDLDKPKPNPPPPVKFRGVAQDEQSLAHPPSYRRRIGRLNRLWIDRRGLPSPARDLSEEQSDRWKYDQSSDDEDDAPVYMLDPFDTKALRYRASIPLQTVTRPPPPVINRQFIPPGAVPQQLAQSSFAPGQPQPQSQPQPNQSQSLPLPQPQQPVAQPQPQPQPQAQPVS