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elt-7

Gene
elt-7
Protein
Transcription factor elt-7
Organism
Caenorhabditis elegans
Length
198 amino acids
Function
Transcriptional activator that binds to the consensus sequence 5'-[AT]GATA[AG]-3' (PubMed:26700680). Required for gut-specific differentiation, specifically acting with the GATA region-binding transcription factor elt-2 to control normal gene expression and promote normal formation of the intestine (PubMed:20807527, PubMed:24257624). May have a protective role in response to infection by Gram-negative bacteria such as P.aeruginosa (PubMed:21168435).
Mass
23.097 kDa
Sequence
MLPETTTLQPLPSVTTIMNEPPARSPMEDYYLFNQFQYNQNPYVYPPQPVYYNTWQDASTHHFDPFQSYQIPSPYEQPIQSSMCTTPLQPLEDSRIIFDESLTKNENEQKSFVEQDSSYESSGNRFGSQKGKKIAKVIRDACCSHCSTTTTTLWRKNDEGNLECNACNLYYRHNKVKRPLSLCKQKPTTRKRRQAKKE