About Products Protein Database Contact

eif4e1b

Gene
Eif4e1b
Protein
Eukaryotic translation initiation factor 4E type 1B
Organism
Mus musculus
Length
244 amino acids
Function
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Similarity
Belongs to the eukaryotic initiation factor 4E family.
Mass
27.985 kDa
Sequence
MNKVEGGGHKEEVVVKEKEVVKEKPSEATAEGVQAGEAKDLPGSLKTQRRKAHREHPPEVLSKLHPLQYRWVLWFFKNDRSRAWQDNLQLVTKFNTVEDFWAVYSHIKLASKLSSGCDYALFKEGILPMWEDNRNKQGGRWLLSIDKQLRHFELDRLWLETLLCLVGNCFEEYSREVCGAVVNIRTKRDKIALWTSEAEDKAGVMQIGQIYKERLGISTKTIIGYQAHADTAAKSNNLANKFVV

Gene
EIF4E1B
Protein
Eukaryotic translation initiation factor 4E type 1B
Organism
Homo sapiens
Length
242 amino acids
Function
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structure.
Similarity
Belongs to the eukaryotic initiation factor 4E family.
Mass
27.596 kDa
Sequence
MLAVEVSEAEGGIREWEEEEKEEEAAERTPTGEKSPNSPRTLLSLRGKARTGGPMEVKLELHPLQNRWALWFFKNDRSRAWQDNLHLVTKVDTVEDFWALYSHIQLASKLSSGCDYALFKDGIQPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLETLLCLIGESFEEHSREVCGAVVNIRTKGDKIAVWTREAENQAGVLHVGRVYKERLGLSPKTIIGYQAHADTATKSNSLAKNKFVV

Gene
eif4e1b
Protein
Eukaryotic translation initiation factor 4E-1B
Organism
Danio rerio
Length
214 amino acids
Function
Does not appear to be a mRNA-cap-binding protein.
Mass
24.745 kDa
Sequence
MASCAVQLIDKVPKKKVEKKKFEPNILKEPCMKHPLQNRWGLWFYKNDKSKMWQDNLRLITKFDTVEDFWGLYNNIQLPSKLSSGCDYSMFKDGIEPMWEDRSNKCGGRWLITLAKQHRHTELDHFWLETLLCLIGEGFSSFSRDICGSVINIRAKGDKIALWTSNAENCETVTYIGRKYKESLGLPQKLVIGYQAHADTATKSNSITKNKFVV