efn-4

Ephrin-4

354 amino acids

Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, involved in ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting together with mab-20 and allows the formation of distinct sensory rays. Probably acts as a ligand for lad-2 to regulate axon guidance of several neurons including SDQL, SDQR, SMD and PLN neurons during neurogenesis.

Belongs to the ephrin family.

39.73 kDa

MKRPLDFLLAICLILLRSSTFADEHTVHWNSTNSMFRNRHPSIEVRLGDVVRFVCPDNEGRKNGEYLTVYEVSEFAMGECALESNSREVIKCGVDTNTEKIIRTHQLPIGESREPPKNVAQFIRSVNPIPNGKEYQPGQTYYYITTSSGKPGGIGQQMYGLCVSKNMRLSMKVLSSQPTPSPSSKPARSRTDARRQEDFITKSSAELMGGQEDEDSENDNAHLLPRDLEIATNPKFRRPSQFDQAAASAGVLDGQFLKVVQMAKEGKTGTFENDREVQKSAEKDAWDPINRHYVADLMNSAYKNANDRVVYQREPDFLIHEEDISTNSLGYSSSSSSSLPTFLIVFLIAVNLLF

efn-4

Ephrin-4

348 amino acids

Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis (PubMed:12679110). In early embryonic development, involved in ventral closure of the epidermis (PubMed:12403719). During male tail morphogenesis, regulates precursor cell sorting together with mab-20 and allows the formation of distinct sensory rays (PubMed:15030761). Probably acts as a ligand for lad-2 to regulate axon guidance of several neurons including SDQL, SDQR, SMD and PLN neurons during neurogenesis (PubMed:26903502).

Belongs to the ephrin family.

39.593 kDa

MKQFFEFLITTFLLLGLAAADEHIVYWNSTNSLFRNRQPTIEVRMGDVVRFVCPDNEEGRNDGEYLIVYEVTEFAMDDCALESHSREVIRCAPEGTAEKVLRTQQLSGGRREDWKKQKVPPKNVAQLIRQLNPIPNGKEYQPGQTYYYMTTSTGKANGTNHRMYGLCESQNMRLSMKVSASQPHPTRRAPTRRQEDFVTTASAELMGGQEDEDSDNDNAHLLPRDLEGSTNPKFRRPSQLETAGVENQQFMKVVQMAQAGKTGTFENEKEAIAQKSSEKDGWHPVNVQYVADLMNNAYQNADERISYQRDFEIHEENDLAVKSLEYSSSSTSLSTNFAILLAVIYVLY