eed-b

Gene

eed-b

Protein

Polycomb protein eed-B

Organism

Xenopus laevis

Length

438 amino acids

Function

Polycomb group (PcG) protein. Component of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity). May play a role in neural induction.

Similarity

Belongs to the WD repeat ESC family.

Mass

49.756 kDa

Sequence

MSEASGRAAGNEMPAKKQKLSSDENSNPELSGDENDDSVSIESGTNTERPDTPTNAANAPGRKGWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNRVTLYECHPQGDIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITMQCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVLSADYDLLGEKIMSCGMDHSLKLWRINSLRMKTAIKESYDYNPNKTNRPFVSQKVHFPDFSTRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIEKIKASESNVTILGRFDYSQCDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTYPKCASAIRQTSFSRDSSVLIAVCDDSTIWRWDRLR

Protein

Polycomb protein eed-B: eed-b