dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)

Length

389 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

41.388 kDa

Sequence

MSRRRAIQPSPALRIGPIELASPVVLAPMAGVTNVAFRALCRQLEQSKVGTVSGLYVCEMVTARALIERHPVTMHMTTFSADESPRSLQLYTVDPDTTYAAARMIAGEGLADHIDMNFGCPVPKVTKRGGGAALPFKRRLFGQIVAAAVRATEGTDIPVTVKFRIGIDDAHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWEQIARLKQHVRTIPVLGNGDIYDAGDALAMMSTTGCDGVVIGRGCLGRPWLFAELSAAFTGSPAPTPPTLGEVADIIRRHGTLLAAHFGEDKGMRDIRKHIAWYLHGFPAGSALRRALAMVKTFDELDCLLDRLDGTVPFPDSATGARGRQGSPARVALPDGWLTDPDDCRVPEGADAMGSGG

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Length

389 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

41.388 kDa

Sequence

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Mycobacterium leprae (strain TN)

Length

384 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

41.1 kDa

Sequence

MLAPMAGVTNVTFRTLCREFGSTRGNLLRPAPPHLRSPLEQSQVGTISGLYVCEMVTARALVERNAVTIHMTTFAPDESPRSLQLYTVDPATTYTAAKMVADEGLADHIDMNFGCPMPKVTRRGGGAALPYKRRLFGQIVAAAVRATEGTKIPVTVKFRIGIDDEHHTHLDAGRIAEAEGAAAVALHARTAAQRYSGTADWAQIAQLKQQVRTIPVLGNGDIYDASDALAMMAVTGCDGVVIGRGCLGRPWLFAELSAAFTGRPAPAPPTLGEVAEIVRRHGKLLVAHFGEDKGMRDIRKHIAWYLHGFPAGSELRNALALVKTLDELDCLLNRLDGAVPFPDAAIGPRGRQGSPAWVALPDSWLTDPDDCTVPIGADIMESGG

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

tRNA-dihydrouridine(20/20a) synthase

Organism

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Length

342 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

Similarity

Belongs to the Dus family. DusA subfamily.

Mass

38.474 kDa

Sequence

MLDPRLSVAPMVDRTDRHFRFLVRQVSLGVRLYTEMTVDQAVLRGNRERLLAFRPEEHPIALQLAGSDPKSLAEAARIGEAFGYDEINLNLGCPSEKAQEGGYGACLLLDLARVREILKAMGEAVRVPVTVKMRLGLEGKETYRGLAQSVEAMAEAGVKVFVVHARSALLALSTKANREIPPLRHDWVHRLKGDFPQLTFVTNGGIRSLEEALFHLKRVDGVMLGRAVYEDPFVLEEADRRVFGLPRRPSRLEVARRMRAYLEEEVLKGTPPWAVLRHMLNLFRGRPKGRLWRRLLSEGRSLQALDRALRLMEEEVGEEGEKEKPGPRGQREAAPGPAREGV

Protein

tRNA-dihydrouridine(20/20a) synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Treponema pallidum (strain Nichols)

Length

340 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

37.161 kDa

Sequence

MQQHALYHPVSIGPLSLKGNVFFAPVAGYSDSAFRSIAIEWEASFTYTEMVSSEAMVRDSLNTKRLIRRASNETHYAIQIFGSNPAVMAETAKLIVDSAQPSCIDINAGCPMPKITKTGAGAALTREPTRLYEVVKAVADAVYAQDARIPVTVKIRAGWEEAHLTWKEAARAAVDAGAQALALHPRTCAQCYAGEANWDIIADLVQCARGWGEVPVFGSGDLHAPEDARAMLEHTACAGVMFARGAMGNPFIFRQTRQLLTEGYYTPVTFEQKLRAAWRELHLLAQDVGESSACKQMRKRFVSYAKGERGKTQWCQRAVHASSFADFAAVIRDACPCIGL

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Rickettsia conorii (strain ATCC VR-613 / Malish 7)

Length

331 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

35.995 kDa

Sequence

MIKIGNIELSSNIILAPMSGVTDLEFRRLVKRFGAGLVVSEMVASRAMIVESRQSLKKSAIMRDDATSACVQLAGCEPNVIAEAAKMNEGMGAKIIDLNFGCPAKKVVGGYSGSALMKDEQLAAKIFEATVEAVKLPVTVKMRMGWDDNTKNAPTLAKIAESSGVQMITVHGRTRCQFYSGNADWDFIRSVKESVKIPVIANGDITNFAKAKEALQKSGADGIMVGRGAYGKPWLISQIDHYLKTGEEKSAPSIAEQLDIVTEHYEAILDYYGESVGVPIARKHIGWYSSGLPNSAEFRGAVNLMNDPLAVKEKIAEFYTSVMETNKLKEF

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Helicobacter pylori (strain ATCC 700392 / 26695)

Length

328 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

37.15 kDa

Sequence

MDFKNKKWLFLAPLAGYTDLPFRSVVKKFGVDVTTSEMVSSHSLVYAFDKTSKMLEKSPLEDHFMAQISGSKESVVKEAVEKINALEHVNGIDFNCGCPAPKVANHGNGSGLLKDLNHLVKLLKTIRENTSKKITSVKVRLGFEKKIPKEIAHALNDAPVDYVVVHGRTRSDKYQKDKIDYESIALMKKILKKPVIANGEIDSVKKAFEVLQITQADGLMIGRAALRAPWIFWQIRNNTTKLPAVVKKDLVLEHFDKMVEFYGDMGVIMFRKNLHAYAKGEMQASAFRNCVNTLTEIKSMRESIEEFFNQEMLQSEVPLWVELNQKSV

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Staphylococcus aureus (strain COL)

Length

328 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

37.767 kDa

Sequence

MKENFWSELPRPFFILAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESFCHPEGIHSVRGRLTFSEDEQPMVAHIWGDKPEQFRETSIQLAKMGFKGIDLNMGCPVANVAKKGKGSGLILRPDVAAEIIQATKAGGLPVSVKTRLGYYEIDEWKDWLKHVFEQDIANLSIHLRTRKEMSKVDAHWELIEAIKNLRDEIAPNTLLTINGDIPDRKTGLELAEKYGIDGVMIGRGIFHNPFAFEKEPREHTSKELLDLLRLHLSLFNKYEKDEIRQFKSLRRFFKIYVRGIRGASELRHQLMNTQSIAEARALLDEFEAQMDEDVKIEL

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Staphylococcus aureus (strain Mu50 / ATCC 700699)

Length

328 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

37.776 kDa

Sequence

MKENFWSELPRPFFILAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESFCHPEGIHSVRGRLTFSEDEHPMVAHIWGDKPEQFRETSIQLAKMGFKGIDLNMGCPVANVAKKGKGSGLILRPDVAAEIIQATKAGGLPVSVKTRLGYYEIDEWKDWLKHVFEQDIANLSIHLRTRKEMSKVDAHWELIEAIKNLRDEIAPNTLLTINGDIPDRKTGLELAEKYGIDGVMIGRGIFHNPFAFEKEPREHTSKELLDLLRLHLSLFNKYEKDEIRQFKSLRRFFKIYVRGIRGASELRHQLMNTQSIAEARALLDEFEAQMDEDVKIEL

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Staphylococcus aureus (strain N315)

Length

328 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

37.776 kDa

Sequence

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Staphylococcus aureus (strain MRSA252)

Length

328 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

37.783 kDa

Sequence

MKENFWSELPRPFFILAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESFCHPEGIHSVRGRLTFSEDEQPMVAHIWGDKPEQFRETSIQLAKMGFKGIDLNMGCPVANVAKKGKGSGLILRPDVAAEIIQATKAGGLPVSVKTRLGYYEIDEWKDWLKHVFEQDIANLSIHLRTRKEMSKVDAHWELIEAIKNLRDEIAPNTLLTINGDIPDRKTGLELAEKYGIDGVMIGRGIFHNPFAFEKEPREHTCKELLDLLRLHLSLFNKYEKDEIRQFKSLRRFFKIYVRGIRGASELRHQLMNTQSIAEARALLDEFEAQMDEDVKLEL

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Staphylococcus aureus (strain MSSA476)

Length

328 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

37.767 kDa

Sequence

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Staphylococcus aureus (strain MW2)

Length

328 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

37.767 kDa

Sequence

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Azospirillum brasilense

Length

328 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

36.098 kDa

Sequence

MAIQIGTISLEGPVILAPMSGVTDLPFRRLVKQSGCGLVVSEMVASQAMIRENRQTLRMVECEPEQFPMAVQLAGCEPDVMAEAAKLNEDRGAAIIDINFGCPVKKVVNGHAGSSLMRDEALAARILEATAKAVTIPVTLKMRKGWDDSSLNAPRLARIAEECGIKLVTVHGRTREQFYNGTADWSFIRSVKEAVSIPVVVNGDITSFDAVDRALAESGADGVMIGRGAYGRPWFPAQVMHYIRTGERLPDPPLHEQLDTLLEHYDAMLTHYGVEGGLRVARKHISWYSTGLRDSAEFRSEVNRMSDPERVRGFIRDFYAPAIERMAA

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Helicobacter pylori (strain J99 / ATCC 700824)

Length

328 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

37.219 kDa

Sequence

MDFKNKKWLFLAPLAGYTDLPFRSVVKKFGVDVTTSEMVSSHSLVYAFDKTSKMLEKSPLEDHFMAQISGSKESVVKEAVEKINALDHVSGIDFNCGCPAPKVANHGNGSGLLKDLNHLVEILKVIRENTNKKITSVKVRLGFEKKIPKEIAHALNDAPVDYVVVHGRTRSDRYQKDKIDYESIALMKKILKKPVIANGEIDSVKKAFEVLQITQADGLMIGRATLRAPWIFWQIRNNTTELPAVVKKDLVLEHFDKMVEFYGDRGVIMFRKNLHAYAKGEMQASAFRNCVNTLTEIKSMRESIEEFFNQEMLQSEVPLWVELNQKSV

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Rickettsia prowazekii (strain Madrid E)

Length

327 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

35.789 kDa

Sequence

MIKIGNIELSSNVILAPMSDVTDLEFRKLVKRFGAGLVVSEMIASRAMIMKSRQSMQKCAIMHDDPTSACVQLAGCEPDVIAEAAKMNEDMGAKIIDLNFGCPAKKVVGGYAGSALMRDEQLAAKIFEATVKAVKIPVTVKMRIGWDDNTRNAPTLAKIAANSGVQMVTVHGRTRCQFYSGNANWDFIRTVKEAVKIPVIANGDITNFAKAKEALQRSGADGIMVGRGVYGKPWLISQIAYYLKTGKEKPAPSIAEQLDIITKHYDAIIDYYGKSVGVPIARKHIIWYSNGLPSSAEFRCTVNLMKDPIAVKEKIAEFYMSVMDANK

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Rickettsia typhi (strain ATCC VR-144 / Wilmington)

Length

327 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

35.691 kDa

Sequence

MIKIGNIELSSNVILAPMSNITDLEFRKLVKRFGAGLVVSEMIASRAMIMKSRQSMQKCAIMHDDPTSACVQLAGCEPDVIADAAKMNEDMGAKIIDLNFGCPAKKVVGGYAGSALMRDERLATKIFEATVKAVKIPVTVKMRMGWDDNTKNAPTLAVIAASSGVQMVTVHGRTRCQFYSGNANWDFIRVVKEAVKIPVIANGDITNFAKAKEALQKSGADGIMVGRGVYGKPWLISQIAYYLKTGKEKPAPSIAEQLDIIIKHYDAIIDYYGKSVGVPIARKHIIWYSSGLPSSAEFRCAVNLMNDPIAVKEKIAEFYMSVMDANK

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Rickettsia bellii (strain RML369-C)

Length

326 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

35.569 kDa

Sequence

MIKIGNIELSSNIILAPMSGVTDLEFRRLVKRFGAGLVVSEMIASRAMIVESRQSLQKCSIMQDDATSACVQLAGCEPNVIAEAAKMNEDMGAKIIDLNFGCPAKKVVNGYSGSALMRDEGLAAKIFEAAVKAVKIPVTVKMRMGWDDQTKNAPTLAKIAERSGIQMVTVHGRTRCQFYSGNADWEFIKNVKEAVKIPVIANGDITNFAKAKEALEKSSADGVMVGRGAYGKPWLISQIDHYLKTGEEKPAPSIESQLDIVLEHYQAIVDYYGESAGVPIARKHMGWYSSGLPNSAEFRGAVNLMNDPIAVKDKIVEFYTSVINRE

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Staphylococcus epidermidis (strain ATCC 35984 / RP62A)

Length

326 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

37.359 kDa

Sequence

MKENFWSTLPRPFFILAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESYCHPEGIHSVRGRLTFSDDEQPMVAHIWGDKPEQFREMSIGLADMGFKGIDLNMGCPVANVAKKGKGSGLILRPETAAEIIQASKAGGLPVSVKTRLGYYDIDEWRDWLKHVFEQDIANLSIHLRTRKEMSKVDAHWELIEAIKTLRDEIAPNTLLTINGDIPDRQTGLELANKYGIDGIMIGRGIFHNPFAFEKEPREHSSKELLGLLRLHLSLFEKYDKDEARHFKSLRRFFKIYVRGIRGASELRHQLMNTQSIAEARELLDTFEARMDARSEV

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Staphylococcus epidermidis (strain ATCC 12228)

Length

326 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

37.358 kDa

Sequence

MKENFWSTLPRPFFILAPMEDVTNIVFRHVVSEAARPDVFFTEFTNTESYCHPEGIHSVRGRLTFSDDEQPMVAHIWGDKPEQFREMSIGLADMGFKGIDLNMGCPVANVAKKGKGSGLILRPETAAEIIQASKAGGLPVSVKTRLGYYDIDEWRDWLKHVFEQDIANLSIHLRTRKEMSKVDAHWELIEAIKTLRDEIAPNTLLTINGDIPDRQTGLELANKYGIDGIMIGRGIFHNPFAFEKEPREHSSKELLGLLRLHLSLFEKYDKDEARHFKSLRRFFKIYVRGIRGASELRHQLMNTQSIAEARELLDTFEARMDARSEV

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)

Length

325 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

35.294 kDa

Sequence

MIKIGDIELSSNVILAPMSDITDLEFRKLVKRFGAGLVVSEMIASRAMVVKSRQSMQKCAIVHDDPTSACVQLAGCEPNVIAEAAKMNEDMGAKIIDLNFGCPAKKVVGGYAGSALMRDEQLAAKIFEATVKAVKIPITVKMRMGWDDNTKNAPDLAKIAESSGVQMVTVHGRTRCQFYSGNADWDFIRSVKEAVKIPVIANGDITNFAKAKEALQKSGADGIMVGRGAYGKPWLVSQIAHYLKTGEEKPAPSIAEQLDIVTEHYNAILDYYGESVGVPIARKHIGWYSSGLPSSAEFRGAVNLMNDPAEVKEKIAEFYTSVMKE

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)

Length

324 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

33.939 kDa

Sequence

MTISLDSLRLDPPVLLAPMAGITDLPFRRMVARFGAGLVVSEMVASGEMLTAKPSVRAKAQAELTAGLPTSVQLAGREAAPMAEAAKIVADMGAEIIDINMGCPAKKVTGGLSGAALMRNPDHALRLIEAVVGAVDLPVTLKMRLGWDEDQLNAAEIAARAEAAGVKMIVIHGRTRMQFYTGAADWRAIAAVRAAVSVPVVANGDITDAASARRALDQSGAAGVMVGRGAQGAPWRLAQIAAALFGKADPKLPSGSEFSDFVSEHYEAILSFYGRDLGLRIARKHLGWYAEAAAAPLRAEMMRATDPAATLALIRSAFSEREAA

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Rhizobium leguminosarum bv. phaseoli

Length

317 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

34.604 kDa

Sequence

MSVRNRVVLAPMSGVTDMPFRELAWRFGAGLVVTEMVASRELVNDTAESWSRLKAAGFRPHMVQLAGREAHWMAEAAKIAADHGADIIDINMGCPAKKVIGGYSGSALMRDPDHALGLIEATVKAVDIPVTLKMRLGWDENSINAPDIARRAEASGIQLVTIHGRTRMQFYEGRADWDAIRAVREVISVPLIANGDVETAHDAQEILRRSGADAVMIGRGCQGRPWHAGVLAGAAEPRREDIADIAVEHYRMMLDFYGEAVAIRHARKHLGWYLERFAPALAGTEKAGIMTSRDPREVAARLYHALDAGALDGREAA

Protein

Probable tRNA-dihydrouridine synthase: dus

Gene

dus

Protein

Probable tRNA-dihydrouridine synthase

Organism

Aquifex aeolicus (strain VF5)

Length

316 amino acids

Function

Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

Similarity

Belongs to the Dus family.

Mass

35.808 kDa

Sequence

MNFKKGEVILAPMASYTHSAFRRLCRRLGADRTYTELISAVGVLRNGIPMKLAYFTEEERPIHIQVFGSNPEEIAQASVVIAKELKPDFIDINFGCSVPKVLRNKAAGYMLQCPPLMGEVVKETVEALKPYGIPVSAKIRLGFEKDEVERIVEELQKAGVSLIAIHARTAKQGFSGKALWHRIKEAKKVASVPIIGSGDVKSWRDIERMFEETECDGVMVGRAALSNPWIFKEFKEKRDIEVGLKERMDFILEELSMMTEYMSREKACAEIKSQIVQILKGVPNSRELKTYIVHAENCKELVKRIEEAKERELLYA

Protein

Probable tRNA-dihydrouridine synthase: dus