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drrB

Gene
drrB
Protein
Doxorubicin resistance ABC transporter permease protein DrrB
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
289 amino acids
Function
Part of the ABC transporter complex DrrABC involved in doxorubicin resistance. Probably responsible for the translocation of the substrate across the membrane (By similarity).
Similarity
Belongs to the ABC-2 integral membrane protein family.
Mass
31.109 kDa
Sequence
MSGPAIDASPALTFNQSSASIQQRRLSTGRQMWVLYRRFAAPSLLNGEVLTTVGAPIIFMVGFYIPFAIPWNQFVGGASSGVASNLGQYITPLVTLQAVSFAAIGSGFRAATDSLLGVNRRFQSMPMAPLTPLLARVWVAVDRCFTGLVISLVCGYVIGFRFHRGALYIVGFCLLVIAIGAVLSFAADLVGTVTRNPDAMLPLLSLPILIFGLLSIGLMPLKLFPHWIHPFVRNQPISQFVAALRALAGDTTKTASQVSWPVMAPTLTWLFAFVVILALSSTIVLARRP

Gene
drrB
Protein
Doxorubicin resistance ABC transporter permease protein DrrB
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
289 amino acids
Function
Part of the ABC transporter complex DrrABC involved in doxorubicin resistance. Probably responsible for the translocation of the substrate across the membrane.
Similarity
Belongs to the ABC-2 integral membrane protein family.
Mass
31.109 kDa
Sequence
MSGPAIDASPALTFNQSSASIQQRRLSTGRQMWVLYRRFAAPSLLNGEVLTTVGAPIIFMVGFYIPFAIPWNQFVGGASSGVASNLGQYITPLVTLQAVSFAAIGSGFRAATDSLLGVNRRFQSMPMAPLTPLLARVWVAVDRCFTGLVISLVCGYVIGFRFHRGALYIVGFCLLVIAIGAVLSFAADLVGTVTRNPDAMLPLLSLPILIFGLLSIGLMPLKLFPHWIHPFVRNQPISQFVAALRALAGDTTKTASQVSWPVMAPTLTWLFAFVVILALSSTIVLARRP

Gene
drrB
Protein
Daunorubicin/doxorubicin resistance ABC transporter permease protein DrrB
Organism
Streptomyces peucetius
Length
283 amino acids
Function
Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Probably responsible for the translocation of the substrate across the membrane.
Similarity
Belongs to the ABC-2 integral membrane protein family.
Mass
30.614 kDa
Sequence
MTTSPGTVESTTPVSGQLRTVLSAGERPARATAVSATLTHLWRAMMAFKHFPVQLIDIVLMPLIFLLMFTYLFGGAFADSTEEYLQFYLPGVTVQAVVMMTVYTGTSLNTDIHKGVFDRFRTLPFWQPATLAGSLLGDVLRYVVALATTVSLGLLLGFRADGGFLGVVGAMLVLIVFGFSVSWIFAALGVVASEPERVSGTSMIVLYPLLFMSNIFVMPETMPGWMQAIVDANPMSHAATASRELMHGTAGFWDVGLVLCVSAGLVAVFAPLTMRLYRNKNAH