Protein
ATP-dependent RNA helicase rok1
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
Similarity
Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
Sequence
MDIFKVLSRGIKAQPKKNQPGAPQLLPSAGAKVNPQFFHDNVGGANAKRGKKRKRKGAQANNATESGDEDDDASDVDYFAPKPTPEELAAKKDAELKADEPKKQKPKLLEENECRQILKSHRLKFTVLAGRVPQDEAATEEKPPKKQKKQKEDRKKQEEEEKKKKKKDEDKKQIYPQPLNSFGELKYTYGIHPVLADNITRQGFRVPTEVQMGSLPLQLRPEMALEKATDVEDVKVEKGIDFLGVAPTGSGKTISFLIPAIDAIIKRRAEDYTPETDEHVLQAIVVAPTRELASQIVNEGRKLAIGTGVRVVLMKRTLRLVAESNEQEETEQEAKEEVQDSDSDSEAESEPEEVMKIDEEEEEEEESDSDAEKKTESRAKGDQKFKKERPITRVDILVTTPKILLNFLCGGEKEKGKPRIIKKTLPTVQSLILDEADVLLDPIFRKQTMGIWRACTHPNLGMTCWSATMASNIEALLTKHIDKRAKRTPEQTPKPLIRLVVGLKDTAVPNITHKLIYTATEPGKLLALRQLLHPVSSADSGPPLRPPFLVFTQTIERAQALHDELKYDIPLEAGGSARVAVLHSSLPDSVRSKIMARFRSGEVWVLITTDVLARGVDFAGVNGVVNYDVPVSAAAYVHRAGRTGRAGREGGVAVTFYTKDDIPFVKSVANVIAMSEKQAGKDIDEKDTVKAAQGSVQKWLLDALPKVAKEDKRKLKVRGVESRRTGGKATITTKSSWERRRENNRREAIEASKRRKREAQKAQKEGGAAPEKAEEEWTGLD