Protein
ATP-dependent RNA helicase dhh1
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
ATP-dependent RNA helicase involved in mRNA turnover, and more specifically in mRNA decapping. Is involved in G1/S DNA-damage checkpoint recovery, probably through the regulation of the translational status of a subset of mRNAs. May also have a role in translation and mRNA nuclear export (By similarity).
Similarity
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
Sequence
MSDQLADQLKATSLSSGPEDWKKGLNLPARDTRQQTEDVTNTRGLDWEDFIHDRDLLMGIFEAGFEKPSPIQEEAIPVALTGRDILARAKNGTGKTAAFVIPALNKINPKVSKIQCLILVPTRELAMQTSQVCKTLGKHLGINVMVTTGGTGLRDDIVRLQDPVHIVVGTPGRILDLAGKQVADLSECPMFIMDEADKLLSQEFTPVIEQLLQFHPKDRQVMLFSATFPLSVKDFSDKNMTSPYEINLMDELTLRGITQYYAFVEEKQKVHCLNTLFSKLQINQSIIFCNSTNRVELLAKKITELGYSCFYSHAKMAQQARNRVFHDFRNGVCRNLVCSDLLTRGIDIQAVNVVINFDFPKNAETYLHRIGRSGRYGHLGLAINLINWDDRFNLYNIERDLGTEIQPIPQTIDKSLYVYENPESIPRPISTFKPIAQQPQQQLQQSQRPQQSQQQQHFSTQTQPSNQLPPQQGNQQLGFNPQAQQPHRPIPQAQGDWQGQNGRQNGTGASNNQPRPTNYQNNRGQPGSSRGGRGRGFQGQGGRQNQNYGGQRGPRTQGQGQPQGPLSAQ