Protein
Dosage compensation protein dpy-30
Organism
Caenorhabditis elegans
Function
Essential for dosage compensation (PubMed:7588066). Required for the sex-specific association of the dosage compensation complex proteins dpy-27 and dpy-26 with the hermaphrodite X chromosomes (PubMed:7588066, PubMed:8939869). Plays a role in developmental rate and body fat regulation downstream of the TOR complex 2 (PubMed:23884442). Required for the robust transdifferentiation of the Y rectal cell to the PDA motor neuron during larval development (PubMed:25124442).
Similarity
Belongs to the dpy-30 family.
Sequence
MADQTASAEVATEKMDTAEAPAAAPAASAAAPAEAESNENTTVPSNVLSANGGQQTGNQSAPRNTSTVPTRQYLDSTVVPILLQGLGALAKDRPENPIEFLANFLLREKDRYNAENQNPAGQQ