dpp11

Asp/Glu-specific dipeptidyl-peptidase

732 amino acids

Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Shows a strict specificity for acidic residues (Asp or Glu) in the P1 position, and has probably a hydrophobic residue preference at the P2 position. Preferentially cleaves the synthetic substrate Leu-Glu-methylcoumaryl-7-amide (Leu-Glu-MCA) as compared to Leu-Asp-MCA.

Belongs to the peptidase S46 family.

82.383 kDa

MRIALVATLVLTSGIANADEGQWQPYQMPSIADKLSERGIDIPAEKLADLTSYPMNAVVGLGYCTASFVSPQGLVVTNHHCAYKAIQYNTKQEHNYLEQGFLATSMDKEPSAGPNERLYITEAVTDVTKDVTKELSQDPLTRYEEIQNNSKALIKNCEVDDNYRCNVRSFHNGLEYYLIKQLMIRDVRLVYAPPESVGGYGGDIDNYEYPRHSGDFAFLRAYVGKDGKPAAYAEDNIPYKPKSYLKVNADGVKAGDGVFVAGYPGTTSRYNLTSELKFASDWLYPTQAKRYQLQIDTINAMGQEDADIAIKYAGNMASMANRMKKLNGLLAGFKATDIIGIKQSREDNFLAWLKQNPKLNQNLIAELEVLLAEQQQVFQSNYYFTNAQSSTLLTAANSLYRLAKEKQKSDAEREIGYQERDLAMFSSRLKRIDSSFHVDVDKTLWQQDLRAYLAQPNRIAALDDALDLNNKETNLEAKLDGLYSLTTLTDQAQRLAWMDADTTTFETSTDPFIRLAVALYDTNMAQEKAEKILDGKLSTARPDYMAAVIEYYKANNWPVYPDANGTLRISYGMVDGYQSRDALYKQPFTRLDGIVAKHTGAEPYNAPQKLLDAISEQRFGDHLVKSVYQDPRGWICRLFSCLDKPEEFNSVPVNFLSSVDTTGGNSGSPVFNGKGELVGLNFDSTYEAITKDWFFNPTITRAVHVDIRYILWMMDKVDHADNLIKELDLVRN

dpp11

Asp/Glu-specific dipeptidyl-peptidase

720 amino acids

Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Shows a strict specificity for acidic residues (Asp or Glu) in the P1 position, and has a hydrophobic residue preference at the P2 position. Preferentially cleaves the synthetic substrate Leu-Asp-methylcoumaryl-7-amide (Leu-Asp-MCA) as compared to Leu-Glu-MCA. Is involved in amino acid metabolism and bacterial growth of asaccharolytic P.gingivalis, that utilizes amino acids from extracellular proteinaceous nutrients as energy and carbon sources.

Belongs to the peptidase S46 family.

81.938 kDa

MKKRLLLPLFAALCLSQIAHADEGMWLMQQLGRKYAQMKERGLKMKEYDLYNPNGTSLKDAVVLFDGGCTGEVVSDRGLVLTNHHCGYDMIQAHSTLEHNYLENGFWAMREADELPNKDISVVFIDKIEDVTDYVKKELKAIKDPNSMDYLSPKYLQKLADKKAGKNFSAKNPGLSVEIKAFYGGNLYLMFTKKTYTDVRLVGAPPSSIGKFGADTDNWIWPRHTGDFSIFRIYADKNGNPAPYSEDNVPLKPKRFFNISLGGVQENDYAMIMGFPGTTHRYFTASEVDEWKSIDNDIRIRMRDIRQGVMLREMLADPQIKIMYSAKYAASQNAYKRAIGANWAIKTRGLRQNKQAMQDRLIAWGAKQGTPRYEEAVHEIDATVAKRADLRRRYWMIEEGIIRGIEFARSPIPTEDETKALQGNDASARKEAIDKIRTRYSKFANKDYSAEVDKKVAVAMLTEYLKEIPYENLPLHLRLVKDRFAGDVQAYVDDIFARSVFGSEAQFDAFAAVPSVEKLAEDPMVLFASSVFDEYRKLYNELRPYDDPILRAQRTYIAGLLEMDGDQDQFPDANLTLRFTYGQVKGYSPRDNVYYGHQTTLDGVMEKEDPDNWEFVVDPKLKAVYERKDFGRYADRSGRMPVAFCATTHTTGGNSGSPVMNANGELIGLNFDRNWEGVGGDIQYLADYQRSIIVDIRYVLLVIDKVGGCQRLLDEMNIVP

dpp11

Asp/Glu-specific dipeptidyl-peptidase

717 amino acids

Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Shows a strict specificity for acidic residues (Asp or Glu) in the P1 position, and has a hydrophobic residue preference at the P2 position. Is likely involved in amino acid metabolism and bacterial growth/survival of asaccharolytic P.endodontalis, that utilizes amino acids from extracellular proteinaceous nutrients as energy and carbon sources.

Belongs to the peptidase S46 family.

81.096 kDa

MNKRFFPTLLLAFVCSTLAYADGGMWLMQQINGQVARMKSLGMQLEAADIYNPNGSSLKDAVVMFDGGCTGVLVSNQGLLLTNHHCGYDQIQKHSSVQHNYLKDGFWSYSLAEELVNPGLEVEIVDEITDVTAAVKKELERIKKPSGLEFLSPRYLSSLAPEIVGKKAASRPGYRYEIKAFYGGNRYYMFTKKVFRDVRLVAAPPSSIGKFGSDTDNWAWPRHTGDFSIFRLYADKNGNPAEYSKDNVPYRPKRWVKVNAQGVKEGDFALIMGYPGTTYKFFTADEVTEWSEIDNNIRIEMRGILQDVMLREMLADPKINIMYAAKYASSQNGYKRAQGANWAIRRRSLREIKLAQQQEVLAWAKQKGIATTEEAVRAISKAIEGRQDLRMRQRYLLEGILMGIEMSNAPAADSDIADHWDDPARREAGLQSIRKQFEAFFNKDYSPEVEKDQLAIALLTRYAERIPAEKQPISIREGIAEYGSAKAYVEMIFDKSIYASRERFEEFMKNPDRDRLLRDPMSRFAASVAYEHQKLAKEVAAFDAPLAAAQRSYVASVLDMKGQPNLAPDANLTLRFTYGEIKGYQPRDVVTYGAKSTLEGVMEKEDPNNWEYVVDPKLKALYEAKNYGRYANSDGSMPVNFCATTHTTGGNSGSPVMNARGELIGLNFDRNWEGVGGDIEYLPNYQRSIILDIRYLLFIIDKFAGCQRLIDEIQPQF

dpp11

Asp/Glu-specific dipeptidyl-peptidase

713 amino acids

Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Shows a strict specificity for acidic residues (Asp or Glu) in the P1 position, and has probably a hydrophobic residue preference at the P2 position. Preferentially cleaves the synthetic substrate Leu-Asp-methylcoumaryl-7-amide (Leu-Asp-MCA) as compared to Leu-Glu-MCA.

Belongs to the peptidase S46 family.

80.756 kDa

MKYLKLFLLLFIIQTQAQQGGMWIPSLLSGMNETEMKNLGMKISADDIYSVNHSSLKDAVPHFNGGCTSEVISPKGLILTNHHCGFDAIQNHSSVDHDYLTNGFWAMKMEDELPNENLVVTFIVSINDVTAQVLDGVASITSETEKQNKIQENITKVTASFAKEAWQENKVRTFFEGNQYILFVTEVFKDVRLVGAPPSLIGKFGSDTDNWVWPRHTGDFSMFRVYANKNNHPAAYSKDNVPYIPKHFLPVSLDGVQEDDFTMVMGYPGKTQEYLPSFAVAQIVNETNPAKIEIREAALKVQDGFMRKDNAIKIQYASKYAGVANYWKKWIGESQGLKKSNAIGLKQNFEKDFQQKVIAAGKQNEYGNLLADFQKYYTEITPYAVSRDYFNEVVVKNTELLSLGYKLYQLEQVFITKGEQAFNDRKENLIKSQADFFKDFNATVDEKVFEQLVALYATKAPKEFLPISLLNVEYKKFAPSIYSKSKLVDYANFKALLSGDAKAVLKKISLDKGYAFVKSLADNYSKNIAPRYDEINLKINALQRIYMKAQLELYPNSRIFPDANSTLRVTYGKVKGYSPKDAIYYNPTTYLDGAIEKYIPGDYEFDVPKKLIDLYNNKDYGQYGENGKLPVCFIGTNHTTGGNSGSPAVDAQGNLIGLNFDRVWEGTMSDIHYDPSICRNVMVDMRYVLFIVDKFAGAKHLINEMKLVHPKKK

dpp11

Asp/Glu-specific dipeptidyl-peptidase

712 amino acids

Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Shows a strict specificity for acidic residues (Asp or Glu) in the P1 position, and has probably a hydrophobic residue preference at the P2 position. Preferentially cleaves the synthetic substrate Leu-Asp-methylcoumaryl-7-amide (Leu-Asp-MCA) as compared to Leu-Glu-MCA.

Belongs to the peptidase S46 family.

80.432 kDa

MKRFFKMALFLGVSALYGQQGGMWIPSLLEGMNAKEMKTLGMKMTVADIYSVNKSSLKDAAPHFNGGCSSEVISDKGLLLTNHHCGYGQIQAHSTLQNDYLANGFWAKSLAEELPNKNLKVTFMVRIDDVTKQVLKGTESITDETEKAKLIEKNIAEVIKTAPKEAWQENSVKAFYDGNQYILFVTETFKDVRLVGAPPSSIGKFGSDTDNWVWPRHTGDFSLFRIYADKNNRPAEYSKDNVPYKPKHFFPISLKGVKEGDFVLVFGYPGTTQEYLPSAAVAQIENVINPARIGIRDIVLKVQDSYMRKDQGIKIKYAAKYARVANYWKKWMGETKGLKKSGAVALKQQQEAKFQQAIQKANKQAQYGNLLSDFNRLYKEIEPYTLAANLNSEFIFRNIDLLSNGSRLLQLEKALEDKGEQSFNDRKKNLLNTFKEIFKDNDKQVDKDVFEKVVVFYAANMPKNLLINSLKNFDAKKLADNLYNNSFLTSLSGVESVLNLSAAEFKERMKNDVGIQFVRELKEMNDTQVFPVYDRLNTQIHALQRTYMKAILEFSKPSDRIFPDANGTLRVTYGKVAGFSPADAVTYSAHTTLDGVMEKYVPGDYEFDVPQHLRDLQAKKDFGRYGDKNGKMPLCFLSTCHTTGGNSGSPAIDANGNLIGLNFDRVWEGTMSDIHYDPKLCRNIMVDIRYVLFVIDKYAGAGHLVNEMKLIK