dld1

Gene

DLD1

Protein

D-lactate dehydrogenase [cytochrome] 1, mitochondrial

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

587 amino acids

Function

Catalyzes the stereospecific oxidation of D-lactate to pyruvate.

Similarity

Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

Mass

65.293 kDa

Sequence

MLWKRTCTRLIKPIAQPRGRLVRRSCYRYASTGTGSTDSSSQWLKYSVIASSATLFGYLFAKNLYSRETKEDLIEKLEMVKKIDPVNSTLKLSSLDSPDYLHDPVKIDKVVEDLKQVLGNKPENYSDAKSDLDAHSDTYFNTHHPSPEQRPRIILFPHTTEEVSKILKICHDNNMPVVPFSGGTSLEGHFLPTRIGDTITVDLSKFMNNVVKFDKLDLDITVQAGLPWEDLNDYLSDHGLMFGCDPGPGAQIGGCIANSCSGTNAYRYGTMKENIINMTIVLPDGTIVKTKKRPRKSSAGYNLNGLFVGSEGTLGIVTEATVKCHVKPKAETVAVVSFDTIKDAAACASNLTQSGIHLNAMELLDENMMKLINASESTDRCDWVEKPTMFFKIGGRSPNIVNALVDEVKAVAQLNHCNSFQFAKDDDEKLELWEARKVALWSVLDADKSKDKSAKIWTTDVAVPVSQFDKVIHETKKDMQASKLINAIVGHAGDGNFHAFIVYRTPEEHETCSQLVDRMVKRALNAEGTCTGEHGVGIGKREYLLEELGEAPVDLMRKIKLAIDPKRIMNPDKIFKTDPNEPANDYR

Protein

D-lactate dehydrogenase [cytochrome] 1, mitochondrial: DLD1

Gene

DLD1

Protein

D-lactate dehydrogenase [cytochrome], mitochondrial

Organism

Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)

Length

576 amino acids

Function

Catalyzes the stereospecific oxidation of D-lactate to pyruvate.

Similarity

Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

Mass

63.097 kDa

Sequence

MFRFVGRSGFALRGSLQLRKDVLRSRTTAVAKRHYSSSNGNNGGGFSSAILSVLGGSLIGGGFVAYALGSQFEKEKSVSDLSIARLEDLDSPEYCDKETFAKALVELKDVLENDPENFTVAKDDLDAHSDTYFNSHHAEANQRPEIVLYPRNTEDVSKLLKICHKYSIPVIPFSGGTSLEGHFLPTRPGSCVVLDISKYLNKIIQLNKEDLDVVVQGGVPWEELNEYLNDHGLLFGCDPGPGAQIAGCIANSCSGTNAYRYGTMKENVVNITMCMADGTIVKTKRRPRKSSAGYNLNGLIIGSEGTLGIVTEATIKCHVRSTFETVAVVPFPTVSDAASCSSHLIQAGIQLNAMELLDDNMMKIINQSGATSKDNWVESPTLFFKIGGRSEQIIQEVIKEVEKIASQHNNTKFEFATDEDSKLELWEARKVALWSTIDTGRKTNPDANIWTTDVAVPISKFADVINATKEEMNASGLLTSLVGHAGDGNFHAFIIYNTEQRKTAETIVENMVKRAIDAEGTCTGEHGVGIGKRDYLLEEVGEDTVAVMRKLKLALDPKRILNPDKIFKIDPNDHQH

Protein

D-lactate dehydrogenase [cytochrome], mitochondrial: DLD1

Gene

dld1

Protein

Dihydrolipoyl dehydrogenase, mitochondrial

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843)

Length

511 amino acids

Function

Lipoamide dehydrogenase is a component of the alpha-ketoacid dehydrogenase complexes (By similarity). Malfunction of this protein blocks the progression of cell cycle from G1 to S phase.

Similarity

Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.

Mass

54.731 kDa

Sequence

MLNSVIKRSALCRFKFTCLQVSECRPAQIEISKRLYSAKASGNGEYDLCVIGGGPGGYVAAIRGAQLGLKTICVEKRGTLGGTCLNVGCIPSKALLNNSHIYHTVKHDTKRRGIDVSGVSVNLSQMMKAKDDSVKSLTSGIEYLFKKNKVEYAKGTGSFIDPQTLSVKGIDGAADQTIKAKNFIIATGSEVKPFPGVTIDEKKIVSSTGALSLSEVPKKMTVLGGGIIGLEMGSVWSRLGAEVTVVEFLPAVGGPMDADISKALSRIISKQGIKFKTSTKLLSAKVNGDSVEVEIENMKNNKRETYQTDVLLVAIGRVPYTEGLGLDKLGISMDKSNRVIMDSEYRTNIPHIRVIGDATLGPMLAHKAEDEGIAAVEYIAKGQGHVNYNCIPAVMYTHPEVAWVGITEQKAKESGIKYRIGTFPFSANSRAKTNMDADGLVKVIVDAETDRLLGVHMIGPMAGELIGEATLALEYGASAEDVARVCHAHPTLSEATKEAMMAAWCGKSIHF

Protein

Dihydrolipoyl dehydrogenase, mitochondrial: dld1