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dhfrV

Gene
dhfrV
Protein
Dihydrofolate reductase type 5
Organism
Escherichia coli
Length
157 amino acids
Function
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
Similarity
Belongs to the dihydrofolate reductase family.
Mass
17.531 kDa
Sequence
MKVSLMAAKAKNGVIGCGPHIPWSAKGEQLLFKALTYNQWLLVGRKTFESMGALPNRKYAVVTRSAWTADNDNVIVFPSIEEAMYGLAELTDHVIVSGGGEIYRETLPMASTLHISTIDIEPEGDVFFPNIPNTFEVVFEQHFSSNINYCYQIWQKG