Protein
Augmin complex subunit dgt6
Organism
Drosophila melanogaster
Function
As part of the augmin complex, plays a role in centrosome-independent generation of spindle microtubules (PubMed:18443220). The complex is required for mitotic spindle assembly through its involvement in localizing gamma-tubulin to spindle microtubules (PubMed:17412918). dgt6 is required for kinetochore fiber formation, mediating nucleation and/or initial stabilization of chromosome-induced microtubules (PubMed:19836241).
Similarity
Belongs to the HAUS6 family.
Sequence
MDRTIIAPWKAEEKEQSEKLHRKLQGLALVHPLPDELRKLIAWDMFLKPNQVAFVHVMHYLFRLLDPAEFKRRFFWPITDKKSEANFRSSTVEYLKHLNEKHQLHWANIKSYLVVMPGGMRFINFLLEFVGFVIQELIKQREKSLGLEAGTPNVSAKVMARQNAVMKEYASSYVVNLEENTALLRDKTQKIRRLMADLSADMGVPEEQLADDGFLDEFEATAALGVERVITQPTERKFDLEASLCGLKEAIDLFQVKQAENNQSKEAVEKALRGMRVLFDCDAVTEGDFYDPLGASKMDALLNGFNRISGTIAEQLDANDHYNESNAFVTTDLQALRVELSQSEVQLNNLLKKLNEPSKKDKGSANASGSARVQTLQPATPRFESVISSKFVSTPPIRIDMGGGGGRNAPVRLALQDDFNGKQFDALSNSLLAPAPPRSARKLKALDQSTGIDLNGTLNRSKINDPMQMLRTIHKNTSKVKAAPQANLSSLGSKWKQMQASFGFDEAPVPGAAVISPQTSPTDPSDPFTPLSGSECTRIERIPRTSENNTSLIAKSAAVIKVLEVSRNVLNLSTSPSGRLDALVPHTESHQQDVAPRLQLNDRTINDSLQLDPDFNIENDKNAFNVSHKFDFDQIGGEDDLQNISDSVLKDIIF