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dddP

Gene
dddP
Protein
Dimethlysulfonioproprionate lyase DddP
Organism
Roseobacter denitrificans (strain ATCC 33942 / OCh 114)
Length
447 amino acids
Function
Able to cleave dimethlysulfonioproprionate (DMSP), releasing dimethyl sulfide (DMS). DMS is the principal form by which sulfur is transported from oceans to the atmosphere. The real activity of the protein is however subject to debate and it is unclear whether it constitutes a real dimethlysulfonioproprionate lyase in vivo: the low activity with DMSP as substrate suggests that DMSP is not its native substrate.
Similarity
Belongs to the peptidase M24B family.
Mass
50.515 kDa
Sequence
MNRHFNATRKIDPSRGATLGDGSPNDMNRVEIGPTQLAFAEWHTARLDLPDLAAMRRFRHRRLTDHVVARGYAGLLMFDPLNIRYATDSTNMQLWNTHNPFRATLLCADGYMVMWDYKNSPFLSEFNPLVREQRAGADLFYFDRGDKVDVAADVFANEVRILLRDHAPGLRRLAVDKVMLHGLRALQAQGFEIMDGEEVTEKARSVKGPDEIRAMRCASHACEVAVRKMEDFARSKVGDGVTCENDIWAILHSENVRRGGEWIETRLLASGPRSNPWFQECGPRVCQRNEIISFDTDLVGAYGICTDISRSWWIGDQKPRADMIYAMQHGVEHIRTNMEMLKPGVMIPELSANTHVLDAKFQKQKYGCLMHGVGLCDEWPLVAYPDHAVAGAYDYPLEPGMTLCVEALISEEGGDFSIKLEDQVLITEDGYENLTKYPFDPALMGVE

Gene
dddP
Protein
Dimethlysulfonioproprionate lyase DddP
Organism
Roseovarius nubinhibens (strain ATCC BAA-591 / DSM 15170 / ISM)
Length
446 amino acids
Function
Able to cleave dimethlysulfonioproprionate (DMSP), releasing dimethyl sulfide (DMS). DMS is the principal form by which sulfur is transported from oceans to the atmosphere (PubMed:19220400, PubMed:20378650). The real activity of the protein is however subject to debate and it is unclear whether it constitutes a real dimethlysulfonioproprionate lyase in vivo: the low activity with DMSP as substrate suggests that DMSP is not its native substrate (PubMed:25140443).
Similarity
Belongs to the peptidase M24B family.
Mass
49.971 kDa
Sequence
MNQHYSETRKIDPSRGATLGDNTPNDNNRIEIGPTQLAFGEWATAGLALPDLQRMREFRWNRLTQAVVDRDYGGVLMFDPLNIRYATDSTNMQLWNAHNPFRALLVCADGYMVIWDYKNSPFLSTFNPLVREQRFGADLFYFDRGDKVDVAADAFSNEVRTLIAEHGGGNMRLAVDKIMLHGLRALEAQGFEIMEGEELTEKTRAIKGPDEILAMRCAVHACETSVAAMEHFAREAVPQGNTSEDDVWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRIIQNNEIISFDTDLIGSYGICVDISRSWWVGDAAPPADMVYAMQHAHEHIMTNMEMLKPGVTIPELSERSHRLDEQFQAQKYGCLMHGVGLCDEWPLVAYPDQAVPGSYDYPLEPGMVLCVEAAVGAVGGNFTIKLEDQVLITETGYENLTSYPFDPALMGR