Organism
Caenorhabditis elegans
Function
In association with pct-1, regulates the trafficking of synaptic vesicle precursors in DA motor neurons by promoting anterograde trafficking to the axon and preventing dynein-dependent trafficking to the dendrite. May also regulate synaptic vesicle trafficking in DD motor neurons and in RIA interneurons (PubMed:20510931). Involved in synapse formation during DD motor neuron remodeling by disassembling ventral presynaptic structures (PubMed:21609829). May activate cdk-5 (PubMed:20510931).
Similarity
Belongs to the cyclin family.
Sequence
MGNSSCCLRTRSSSGEDKSYNNDGQYIRTNQVEFQYVNQVFPRDETSTNFLPHISEREVTEGYEEDPSTNPTARPTFMERSKSEMKLKDNRRSCYMLDALAAGGHHPGILPRSLRKSSSCSTIYIDDSTVSQPHLKNTIKCISLAIYYHISNRKNRGHERLMEIFEERLHPIFRDPIPPEQMTRDPDHRNIYRFVRNLFSSAQLTAECAIITLVYIERLLNYAEMDLCPSNWRRVVLGSIMLASKVWDDQAVWNVDYCQILRDTNVDDMNELERRFLECLDFNIEVPSSVYAKYYFDLRTLALANDLQLPIQPLYKERAQRLEALSRVFEDKIQSSSLPKRARSAEHLVFEHPAVLS