cyt-19

ATP-dependent RNA helicase cyt-19, mitochondrial

626 amino acids

Acts as an RNA chaperone to resolve non-native structures formed during RNA folding to promote mitochondrial group I, but also group II, intron splicing. Functions predominantly by disrupting accessible RNA secondary structure and depends on spontaneous openings in tightly packed RNAs to gain access to RNA helices.

Belongs to the DEAD box helicase family.

69.397 kDa

MRTSVLRQAGLCRAALAARHLQISSKPSAALLSQVTRAIAVQSLPSASLPRFYSAEATAQSNTAASNGLVTRFADLAALGVHENVVRAITHGMGYENMTEVQSMTISPALKGKDIVAQAKTGTGKTLGFLVPVIQKIITQDPDLAHRFGGKRARSDDIRAIIISPTRELAEQIGEEARKLVKGTGIIVQTAVGGTQKNAMLYKTRQQGCHILVGTPGRLNDLLSDSHSGIDAPRLSTLVLDEADRMLEVGFNEELRQIINYLPDRKVLPRQTLLYSATIPKDVVGLARSYIDKNNFEFVQTVKADEVLTHDRIPQYIVPCKGFENIYPAMLELIEKALNESRTNPEALPFKAIVFLPTTAEVIMANAIFKRLQWKFKHIPKTWDIHSKLTQNARTRAADEFKNARTGILFSSDVTARGMDFPNVSHVIQTHIPPNREQYIHRLGRTGRANKPGQGWLIVPDIELHAARSRLPGLPIKRNDELECASVNAADSGADKHANFQHILDAASRLPEDLFKDCYSSYLGGALQGIDRQALVYALNDLAKFGWGLEEPPAVRQSIMKHMGRVQGLRVETREHSMRPMGSGPGHRRDFNSRGPRRQSDDPFENALHRAQDLDRRPTRRQQASF