Protein
Cytochrome P450 2K6
Function
Metabolizes aflatoxin B1 (AFB1) to the cytotoxic derivative AFB1 exo-8,9-epoxide. Does not show activity towards lauric acid.
Similarity
Belongs to the cytochrome P450 family.
Sequence
MALIEAFLLQGSPTGTILGALLLFLVIYLFSSSSSSQDKEKYPPGPKPLPLLGNLHILDLKKTYLSLLELSKKYGPIYTVYLGPKKVVILSGYKIVKEALVNLSEEFGDRDISPIFHDFNRGYGIAFSNGENWREMRRFALSTLRDFGMGRKRSEELIIEEIKYVKEEFEKFGGNPFETKLPLALAISNIIASIVFSVRFEYSNTKLHRMVGRAYENMKLTGSPSVQIYNMFPWLRPIVANRNQIVKNLRDTFKQNEELINGVMKTLDPFNPRGIVDSFLIRQQKDEESGKTDSLYNSNNLYCTVNNLFGAGTDTTVTTLRWGLLLMAKYPEIQAKVQDEIERVIGGRQPVVEDRKNLPYTDAVIHEIQRFADISPIGAPRQTTCDVHLNGYFIKKGTPVFPLLVSVLRDENEWETPDSFNPKHFLNKQGQFVKKDAFMPFGAGRRVCIGESLARMELFLFFTSLLQYFRFTPPPGVSEDDLDLTPVVGFTLNPKPHQLCAVKRS