Protein
Pre-mRNA-splicing factor cwf5
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Function
Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome. Binds to RNA (By similarity). Involved in pre-mRNA splicing.
Similarity
Belongs to the RRM SLT11 family.
Sequence
MSHGPKGDINKQEWEDVEFPSICERCLGDNSYVRMTKEPLGQECKICSKPCTIFRWIKERGQKPGKTQICVGCARYKNCCQSCMLDLQFGLPIALRDAALKLVESGPTNDINREFFAQNQQRLLSNGETAYDSQEASAAARNLVKKVEKRELHSRPPKRKLDDVESKQILKEARASDASLNAERPLFPVKKIINGNVSLSINMEPPKDKKIASLFLIGVEDELADYKIRKHFEQYGPLKSVVCSHRAKCAFVNFKTRSSAEIAAAASPDGNVVIEGFRLKVQWGKPRSLGGPEGEVRNAKLADLVMRGSSHGNKTSQKSTIKNIENEDHENTKSPAVAIPIDPNQPRYRSQIPR