Protein
Pre-mRNA-splicing factor cwf4
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Function
Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity).
Similarity
Belongs to the crooked-neck family.
Sequence
MTSEAPRVKNKNPAPIQISAEQLLREAVERQDVAFVPPKINITDLEELQEFQGRKRKEFEDAIRRNRLAMGHWMRYGQWELDQKEFARARSVFERALDVDSTYIPLWLKYIECEMKNRNINHARNLFDRAVTQLPRVDKLWYKYVYMEEMLGNITGCRQVFERWLKWEPDENCWMSYIRMERRYHENERARGIYERFVVVHPEVTNWLRWARFEEECGNAANVRQVYLAAIDALGQEFLNERFFIAFAKFEIRQKEYERARTIFKYAIDFMPRSKSMELYKEYTHFEKQFGDHLGVESTVLDKRRLQYEKLLKDSPYDYDTWLDLLKLEESAGDINTIRETYEKAIAKVPEVVEKNAWRRYVYIWLNYCLFEEIDVKDVDRARKVYQEALKLIPHKKFTFAKLWLMYAMFELRQRKIDVARKTLGRALGMCPKPKLFRGYIEFEDAIKQFDRCRILYEKWILYDPEACAPWLGYAALETKLGDSDRARALYNLAVNQPILETPELVWKAYIDFEFEEMEYGKARSIYQQLLRTAPHVKVWISFANFEIAHLEDDDEEPPNEEVASPTAVVRARNVFENALAHLRQQGLKEERVVLLEAWKQFEAMHGTEDTRKHVSSLMPQVVKKRRRLEDGSFEEYLDYLFPDTATDQGDKMRKMLELSRKWKEEMAKKKLEA