Protein
Peptidyl-prolyl isomerase cwc-27
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Involved in pre-mRNA splicing (By similarity).
Similarity
Belongs to the cyclophilin-type PPIase family. CWC27 subfamily.
Sequence
MSAIYNLEPQPTASAIIHTTQGEIAVELFAKQTPLTCRNFLQLALDGYYDNTIFHRLIPGFIVQGGDPSGTGHGGESIYDNGALSGDLDPWPMDQRRGKNAGPHGVNFKDEFHSRLKFNRRGLLGMANEGAPDTNSSQFFFTLGKADELTGKNTMFGRVAGDTIYNLAKIGEAEVEEGGERPLYPIKITRIEILINPFDDMQKREKKPRPQQISRPTPAEKKQKKRKGGKQLLSFGDEVGDEDGEELPLPKKPKFDTRIVADLDQDDSSKQSASKKSSAKRDAKPVANDVPKREEKPEPKPVKESRRSPSPQPVAQKKEQPPKKHYSEHSSPEPEEPKKKSLLEKTNEEIAALKASMKRTIHSEPVKQEKKKSALEQLIPDTAIRGRKRRPGASSNPTREEQEALDLLKSFKAKIETAPPEKNAAQPAVNPDVEDGEQDGQADEEKVCDLHFIANCQSCKAWDKVEDNEDSGDEGWMSHKLSFAADKLGKDLSYRKKAEEELVVIDPLAKARTLKEEKKATRDAKTGGSSRAWDRGRRDRH