ctaDI

Cytochrome c oxidase subunit 1-alpha

554 amino acids

Subunit I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer.

Belongs to the heme-copper respiratory oxidase family.

62.013 kDa

MSAQISDSIEEKRGFFTRWFMSTNHKDIGVLYLFTAGLAGLISVTLTVYMRMELQHPGVQYMCLEGMRLVADAAAECTPNAHLWNVVVTYHGILMMFFVVIPALFGGFGNYFMPLHIGAPDMAFPRLNNLSYWLYVCGVSLAIASLLSPGGSDQPGAGVGWVLYPPLSTTEAGYAMDLAIFAVHVSGATSILGAINIITTFLNMRAPGMTLFKVPLFAWAVFITAWMILLSLPVLAGGITMLLMDRNFGTQFFDPAGGGDPVLYQHILWFFGHPEVYMLILPGFGIISHVISTFARKPIFGYLPMVLAMAAIAFLGFIVWAHHMYTAGMSLTQQTYFQMATMTIAVPTGIKVFSWIATMWGGSIEFKTPMLWALAFLFTVGGVTGVVIAQGSLDRVYHDTYYIVAHFHYVMSLGALFAIFAGTYYWIGKMSGRQYPEWAGQLHFWMMFIGSNLIFFPQHFLGRQGMPRRYIDYPVEFSYWNNISSIGAYISFASFLFFIGIVFYTLFAGKPVNVPNYWNEHADTLEWTLPSPPPEHTFETLPKPEDWDRAQAHR