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csa5

Gene
csa5
Protein
CRISPR type I-A cluster 1/Apern-associated protein Csa5-1
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Length
162 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
Mass
18.523 kDa
Sequence
MEASEPVAETISKRFWTLIKMLRFYVVLRRFGYIDPLIYSIDPKQIKDVLSEALREFVSYTSSSSSRSIVIYDDPKNPVTAQAPCLVVAKRDEIPQNFPSIYRYTIYKIDKSSEYCISPLVVNDKYATLITPNESVIKEFFDKLDSNIQYARVLASLAVGGE

Gene
csa5
Protein
CRISPR type I-A cluster 2/Apern-associated protein Csa5-2
Organism
Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Length
150 amino acids
Function
In strain P2 toxic when expressed in vivo in the absence of CRISPR loci A-D (strain P2 contains 6 CRISPR loci in all). It causes strong growth inhibition, a significant proportion of cells have degraded or no DNA by 20-24 post-induction (PubMed:25277654).
Mass
16.487 kDa
Sequence
MAQKSEKENIIGRIANLLAVGFLYSESPTLVDRFANALSKEAVTKVLYDVQRIVQMGIDRSEIATTTITIQGKDYPAQGKDYPAVNVNSSGAKYTVVGYLPTSQDIEDFLRMIEEDVYYARKAGALAMSIANRIKLGSKQSKSEQGGEKK

Gene
csa5
Protein
CRISPR system associated protein Csa5
Organism
Thermoproteus tenax (strain ATCC 35583 / DSM 2078 / JCM 9277 / NBRC 100435 / Kra 1)
Length
130 amino acids
Function
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (By similarity).
Mass
15.036 kDa
Sequence
MESVQLKKEELVERAARSVRPAVHLEMAYDVLDELSRSPEKYPEQLAKLSRIVVKVLNDVEDELEHNPQNEELQKARNRLAAWGGYVAELAKRLEEADDRERIRMVRLFCAMALAPDKLTVELKKLLKGR