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crtB

Gene
crtB
Protein
Phytoene synthase
Organism
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Length
355 amino acids
Function
Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (By similarity).
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
38.987 kDa
Sequence
MIASADLDACREMIRTGSYSFHAASRLLPERVRAPSLALYAFCRVADDAVDEAVNDGQREEDAEVKRRAVLSLRDRLDLVYGGRPRNAPADRAFAAVVEEFEMPRALPEALLEGLAWDAVGRSYDSFSGVLDYSARVAAAVGAMMCVLMRVRDPDVLARACDLGLAMQLTNIARDVGTDARSGRIYLPRDWMEEEGLPVEEFLARPVVDDRIRAVTHRLLRAADRLYLRSEAGVCGLPLACRPGIYAARHIYAGIGDEIARNGYDSVTRRAFTTRRQKLVWLGLSATRAALSPFGPGCATLHAAPEPEVAFLVNAAARARPQRGRSEALISVLAQLEAQDRQISRQRLGNRANPI

Gene
crtB
Protein
Phytoene synthase
Organism
Streptomyces griseus
Length
342 amino acids
Function
Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (By similarity).
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
37.137 kDa
Sequence
MTVHELDAAGIHDPALRAAYTRCRGLNARHGKTYFLATRLLPVDRRPAVHALYGFARWADDIVDDLDTPATPGERARALLGLEAQLEAGLRGARAAEPVIRALADTAARYTIDHRHFTDFLSSMRSDLTVGGYASYEELGRYMHGSAAVIGLQMLPVLGTVVAREEAAPHAAALGVAFQLTNFLRDVGEDLDRGRLYLPTELLAAHGADRDRFEWSRSTGMPDSRITDVLRAAAAHNRAVYRAALPGIAMLAPVSRPCIRTAFVLYSGILDAIEADGYAVLHRRAVVPRRRRAAVALDGLVRAVAVRTVCRRRADAVDASRSAELSRPRTAGGPAPVRREAV

Gene
crtB
Protein
Phytoene synthase
Organism
Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Length
339 amino acids
Function
Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (By similarity).
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
37.302 kDa
Sequence
MIAEADMEVCRELIRTGSYSFHAASRVLPARVRDPALALYAFCRVADDEVDEVGAPRDKAAAVLKLGDRLEDIYAGRPRNAPSDRAFAAVVEEFEMPRELPEALLEGFAWDAEGRWYHTLSDVQAYSARVAAAVGAMMCVLMRVRNPDALARACDLGLAMQMSNIARDVGEDARAGRLFLPTDWMVEEGIDPQAFLADPQPTKGIRRVTERLLNRADRLYWRAATGVRLLPFDCRPGIMAAGKIYAAIGAEVAKAKYDNITRRAHTTKGRKLWLVANSAMSATATSMLPLSPRVHAKPEPEVAHLVDAAAHRNLHPERSEVLISALMALKARDRGLAMD

Gene
crtB
Protein
15-cis-phytoene synthase
Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Length
337 amino acids
Function
Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield 15-cis-phytoene.
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
38.707 kDa
Sequence
MANGQISPQRAVTKPQSWWLTSEPRPSLMLQLPKPSPSAKPCASVEEAYEICRQVTAQYAKTFYLGTLLMPPAKRRAIWAIYLWCRRTDELVDGPQAATTTPETLDHWERRLEGIFAGQPQDDADVALVDTLETFPLDIQPFRDMIAGQRMDLYRSRYQTFEELDLYCYRVAGTVGLMSSAVLGVDTGNGQAPWQPDAVYIPQEEAIALGVANQLTNILRDVGEDVERGRIYLPLEDLERFNYSEQDLLNGVNDDRWRSLMKFEIDRARHYFEDAERGIRALNRDARWPVWTALMLYKGILDVIEANNYNVFNRRAYVPTPKKLLYLPVAWLRAQVL

Gene
crtB
Protein
Phytoene synthase
Organism
Arthrospira platensis
Length
309 amino acids
Function
Catalyzes the reaction from prephytoene diphosphate to phytoene.
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
35.945 kDa
Sequence
MLQLSKSPCMRTPATRSDSYELCRQITAQYAKTFYLGTQLMPLAKRQAIWAIYVWCRRTDELVDGPMASSTTLETLDHWEEQLESIFAGHPIEPVDVALVDTLGRFPLDIQPFRDMIAGQRMDLSRNRYNTFDELNLYCYRVAGTVGLMSLAVMGTAEPDLSVPWNRDQSIYYPKEEAIALGIANQLTNILRDVGEDARRGRIYLPLDDLALFNYTEADLLNGKVDERWRELMRFQIQRARKFYTLAEEGIAALHPDIRWPVWTALMLYRQILDEIERNEYDVFNQRAYVPTWKKMMCLPLAQLRARVL

Gene
crtB
Protein
15-cis-phytoene synthase
Organism
Pantoea ananas
Length
309 amino acids
Function
Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield the 15-cis-phytoene isomer.
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
34.472 kDa
Sequence
MNNPSLLNHAVETMAVGSKSFATASKLFDAKTRRSVLMLYAWCRHCDDVIDDQTLGFQARQPALQTPEQRLMQLEMKTRQAYAGSQMHEPAFAAFQEVAMAHDIAPAYAFDHLEGFAMDVREAQYSQLDDTLRYCYHVAGVVGLMMAQIMGVRDNATLDRACDLGLAFQLTNIARDIVDDAHAGRCYLPASWLEHEGLNKENYAAPENRQALSRIARRLVQEAEPYYLSATAGLAGLPLRSAWAIATAKQVYRKIGVKVEQAGQQAWDQRQSTTTPEKLTLLLAASGQALTSRMRAHPPRPAHLWQRPL

Gene
crtB
Protein
Phytoene synthase
Organism
Escherichia vulneris
Length
309 amino acids
Function
Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (Probable).
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
34.123 kDa
Sequence
MSQPPLLDHATQTMANGSKSFATAAKLFDPATRRSVLMLYTWCRHCDDVIDDQTHGFASEAAAEEEATQRLARLRTLTLAAFEGAEMQDPAFAAFQEVALTHGITPRMALDHLDGFAMDVAQTRYVTFEDTLRYCYHVAGVVGLMMARVMGVRDERVLDRACDLGLAFQLTNIARDIIDDAAIDRCYLPAEWLQDAGLTPENYAARENRAALARVAERLIDAAEPYYISSQAGLHDLPPRCAWAIATARSVYREIGIKVKAAGGSAWDRRQHTSKGEKIAMLMAAPGQVIRAKTTRVTPRPAGLWQRPV

Gene
crtB
Protein
15-cis-phytoene synthase
Organism
Synechococcus elongatus (strain PCC 7942)
Length
308 amino acids
Function
Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield 15-cis-phytoene.
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
35.891 kDa
Sequence
MLQMIPARPSRALASLSEAYEECRQITARYAKTFYLGTLLMPEAKRQAIWAIYVWCRRTDELVDGPQAAQTNFATLDAWERRLERLFAGEPEDDCDVALVDTLARYPLDIQPFRDMIEGQRMDLLQNRYSTFEDLYTYCYRVAGTVGLMSQPVMGIESTNSRAPWDPTTPPDPTQEALALGIANQLTNILRDVGEDARRGRIYLPQEELAQFNYSEQDLFNGVIDDRWRAFMQFQLDRARDYFEQAERGIRQLSHDARWPVWASLMLYREILDVIEQNNYDVFRKRAYVPTWRKLCSLPVAMLRATVL

Gene
crtB
Protein
15-cis-phytoene synthase
Organism
Paracoccus sp. (strain N81106 / MBIC 01143)
Length
304 amino acids
Function
Involved in the biosynthesis of carotenoids for the production of astaxanthin. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield 15-cis phytoene.
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
33.03 kDa
Sequence
MSDLVLTSTEAITQGSQSFATAAKLMPPGIRDDTVMLYAWCRHADDVIDGQALGSRPEAVNDPQARLDGLRADTLAALQGDGPVTPPFAALRAVARRHDFPQAWPMDLIEGFAMDVEARDYRTLDDVLEYSYHVAGIVGVMMARVMGVRDDPVLDRACDLGLAFQLTNIARDVIDDARIGRCYLPGDWLDQAGARVDGPVPSPELYTVILRLLDAAELYYASARVGLADLPPRCAWSIAAALRIYRAIGLRIRKGGPEAYRQRISTSKAAKIGLLGIGGWDVARSRLPGAGVSRQGLWTRPHHA

Gene
crtB
Protein
Phytoene synthase
Organism
Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Length
302 amino acids
Function
Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (Probable).
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
33.142 kDa
Sequence
MTEIEQAYRITESITRTAARNFYYGIRLLPREKRAALSAVYALGRRIDDVADGELAPETKITELDAIRKSLDNIDDSSDPVLVALADAARRFPVPIAMFAELIDGARMEIDWTGCRDFDELIVYCRRGAGTIGKLCLSIFGPVSTATSRYAEQLGIALQQTNILRDVREDFLNGRIYLPRDELDRLGVRLRLDDTGALDDPDGRLAALLRFSADRAADWYSLGLRLIPHLDRRSAACCAAMSGIYRRQLALIRASPAVVYDRRISLSGLKKAQVAAAALASSVTCGPAHGPLPADLGSHPSH

Gene
crtB
Protein
Phytoene synthase
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Length
302 amino acids
Function
Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (By similarity).
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
33.142 kDa
Sequence
MTEIEQAYRITESITRTAARNFYYGIRLLPREKRAALSAVYALGRRIDDVADGELAPETKITELDAIRKSLDNIDDSSDPVLVALADAARRFPVPIAMFAELIDGARMEIDWTGCRDFDELIVYCRRGAGTIGKLCLSIFGPVSTATSRYAEQLGIALQQTNILRDVREDFLNGRIYLPRDELDRLGVRLRLDDTGALDDPDGRLAALLRFSADRAADWYSLGLRLIPHLDRRSAACCAAMSGIYRRQLALIRASPAVVYDRRISLSGLKKAQVAAAALASSVTCGPAHGPLPADLGSHPSH

Gene
crtB
Protein
Phytoene synthase
Organism
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Length
302 amino acids
Function
Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (By similarity).
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
33.142 kDa
Sequence
MTEIEQAYRITESITRTAARNFYYGIRLLPREKRAALSAVYALGRRIDDVADGELAPETKITELDAIRKSLDNIDDSSDPVLVALADAARRFPVPIAMFAELIDGARMEIDWTGCRDFDELIVYCRRGAGTIGKLCLSIFGPVSTATSRYAEQLGIALQQTNILRDVREDFLNGRIYLPRDELDRLGVRLRLDDTGALDDPDGRLAALLRFSADRAADWYSLGLRLIPHLDRRSAACCAAMSGIYRRQLALIRASPAVVYDRRISLSGLKKAQVAAAALASSVTCGPAHGPLPADLGSHPSH

Gene
crtB
Protein
15-cis-phytoene synthase
Organism
Enterobacter agglomerans
Length
295 amino acids
Function
Involved in the biosynthesis of carotenoids. Catalyzes stereoselectively the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield 15-cis-phytoene.
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
32.786 kDa
Sequence
MEVGSKSFATASKLFDAKTRRSVLMLYAWCRHCDDVIDDQVLGFSNDTPSLQSAEQRLAQLEMKTRQPMRIQMHEPAFAAFQEVAMAHDILPAYAFDHLAGFAMDVHETRYQTLDDTLRYCYHVAGVVGLMMAQIMGVRDNATLDRACDLGLAFQLTNIARDIVEDAEAGRCYLPAAWLAEEGLTRENLADPQNRKALSRVARRLVETAEPYYRSASAGLPGLPLRSAWAIATAQQVYRKIGMKVVQAGSQAWEQRQSTSTPEKLALLVAASGQAVTSRVARHAPRSADLWQRPV

Gene
crtB
Protein
Phytoene synthase
Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length
289 amino acids
Function
Involved in the biosynthesis of carotenoids. Catalyzes the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield phytoene (Probable).
Similarity
Belongs to the phytoene/squalene synthase family.
Mass
31.964 kDa
Sequence
MKMPASMEPDWKALLRVLRAHSATFYLGSLLFPKEARKGAWAVYAACRLGDEAVDGEGGGPEALEAWWAGVERAYRGRPLAEWEKGLAWALERWDIPFEAFLHMREGFLTDLGPVRLGTEAELLRYCYQVAGTVGRMMAPIAGGGKEAEARAVKLGQAMQLTNILRDVGEDLERDRVYLPLDLLRAHGVEVEDLRAGRVTPGYRALMAHLEGKARALYREGLAGLGHLKVGRAAIALAALQYRGILDKLRLSGYDNLGRRAHLKAWERALLLPKAFLAARFPPRPEGSP