Protein
Probable DNA-binding protein creA
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)
Function
Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Represses the transcription of the alcR, alcA and aldA genes by binding to a GC-rich region in their promoter. Plays also a role in response to carbon starvation and the control of extracellular proteases activity (By similarity).
Similarity
Belongs to the creA/MIG C2H2-type zinc-finger protein family.
Sequence
MGFSDLLNPQNPESTPSTPANKSSAPSTPSTGQSNSNMTSVSLLPPLMKGARPANEEPRQDLPRPYKCPLCDRAFHRLEHQTRHIRTHTGEKPHACQFPGCTKRFSRSDELTRHSRIHNNPNSRRNNKAQHLAAAAAAAAANQDNALASNAASMMPPPSKPITRSAPVSQVGSPDISPPHSFSNYAGHMRSNLGPYARNSDRASSGMDINLLATAASQVERDEHYGFHNGPRGHHIFGSRHHNSNRLPSLSAYAISQNMSRSHSHDEDDMYSHRVKRSRPNSPNSTAPSSPTFSHDSLSPTPDHTPLATPAHSPRLRPLGTSELQLPSIRHLSLHHTPALAPMEPQPEGPNYYSPTQPHVGPSISDIMSKPDGTQRKLPVPQVPKVAVQDLLSPGFTSVSSSASNSVAGGDLADRF