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crad

Gene
CRAD
Protein
Cancer-related regulator of actin dynamics
Organism
Homo sapiens
Length
1233 amino acids
Function
Involved in epithelial cell integrity by acting on the maintenance of the actin cytoskeleton. Positively regulates the actin polymerization, by inhibiting the interaction of actin-capping proteins with actin.
Mass
136.76 kDa
Sequence
MGTRAFSHDSIFIPDGGAESEQTVQAMSQDNILGKVKTLQQQLGKNIKFGQRSPNAIPMNKANSGEASLEEDLFLTSPMEIVTQQDIVLSDAENKSSDTPSSLSPLNLPGAGSEMEEKVAPVKPSRPKRHFSSAGTIESVNLDAIPLAIARLDNSAAKHKLAVKPKKQRVSKKHRRLAQDPQHEQGGLESRPCLDQNGHPGEDKPTWHEEEPNPLDSEEERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGQEPPLEAERAPREEQQRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELEQQEAEVQGPPEALEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQERLKPEGQREHSEEPGICEEQNPEAERRREQQGRSGDFQGADRPGPEEKREEGDTEPLLKQEGPVEAAQPPVERKEAAALEQGRKVEELRWQEVDERQTMPRPYTFQVSSGGKQILFPKVNLSPVTPAKDTGLTAAPQEPKAPKASPVQHALPSSLSVPHTAILVTGAQLCGPAVNLSQIKDTACKSLLGLEEKKHAEAPAGENPPRGPGDARAGSGKAKPRQESPSSASALAEWASIRSRILKNAESDPRSSERDQLRPGDESTPRGRCDSRGNQRKTPPVNAKFSIMPAWQKFSDGGTETSKQSTEAESIRKRPMLGPSEETAPQPPPAGVRELGKGPEKSEMHREPADTTEGCKFAKDLPSFLVPSLPYPPQKVVAHTEFTTSSDSETANGIAKPDPVMPGGEEKASPFGIKLRRTNYSLRFNCDQQAEQKKKKRHSSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKAANKMPLAQKPALAPKPTSQTPPASPLSKLSRPYLVELLSRRAGRPDPEPSEPSKEDQESSDRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQQEKPSQTPEAGRKEKPMLQSRHSLDGSKLTEKVETAQPLWITLALQKQKGFREQQATREERKQAREAKQAEKLSKENVSVSVQPGSSSVSRAGSLHKSTALPEEKRPETAVSRLERREQLKKANTLPTSVTVEISDSAPPAPLVKEVTKRFSTPDAAPVSTEPAWLALAKRKAKAWSDCPQIIK
Protein
Cancer-related regulator of actin dynamics: CRAD

Gene
Crad
Protein
Cancer-related regulator of actin dynamics
Organism
Mus musculus
Length
1207 amino acids
Function
Involved in epithelial cell integrity by acting on the dynamics of the actin cytoskeleton (PubMed:30361697). Positively regulates the actin polymerization, by inhibiting the interaction of actin-capping proteins with actin (By similarity).
Mass
132.286 kDa
Sequence
MGARAFSHDSIFIPDGGAESEQTVQAMSQDNILGKVKTLQRQLGKNIKFGQRPSNAIPMKKAGSTDASSEEDFVLTSPMEIVTQQDIVPSDTENKSSDTPSSSSPLNLPEAGSDMEEKVAPVKPSRPKRHLSSAGTIESVNLDAIPLAIARLDNSAARHKLAVKPKNQRVSRKHRWLAQDRQNEPGSFESQSSLDQNGQLGEDKHIWHGEEPEPLESHEEKRLHEEYWRELEAKCKRQKAEAAEKRRQEEQRRQALERRLWEESLRQELLEEEEEGEEEEEVKEEGEEGEEVGLQPRAGKVPPEEGHQSGPEEQRCTEQELGGADDPARLEAEERRREQEEAERQAEKLRQREAESQEEELRQREAERQRAQEEDAKGMLQEEEEEAKRIEELKGKETPEPLVEEGPQSPEGESQPWLTDDADQRSPLQRDLEKPGEREREDLESAGQREIAEEPRGEGEPAEQSGDLDAHCGGVDGEGKETAQTDSPQPQERQMEGTPAPEENEATAADIDRKVEELRWQEVDERQTMPRPYTFQVSSGSRQILFPKVNLSPVTPAKDASLAPAAQEPPAPRGAASHALPSALSIPHTAILVTGAQLCGPAVNLSQIKDTACKSLLGLSEEKRPMDVPTVESRAGSGKSRPAPESPSNAAALAEWASIRSRILKNSEGDQRGDREPARAGDEPVPRARCDSRGNVRRTPPVNAKFSIMPAWQKFSDSGAETFRQSLDGESGRKKPGLAPSEETAPQPHAAAQQEVSQEPPDTTDGCKFAKDLPSFLVPGLPSPQKAASRTESTTTLDSETTSDVGNPDPAMPGGEEKASPFGIKLRRTNYSLRFHCDQQAEQKKKKRHSSTGDSVGGATPATGSVSGESEPEATFLKHGPSLPQERKPALSPRKDSAESHSSGHYVAVAQSGLPPASGQTPAPEQDRAVSKMPSMQKPALAPKPASQTPPSSPLSKLSRPHLVELLARRAGKLDSEPSETAKESSDNQPPSPSLPEELKGQKRDEKDVPEKKPASPPLPAGQQERPSLIPETGRKEKPVLQSRHSLDGSKVTEKVETAQPLWITLALQKQKGFREQQATREERKQAREAKQAEKLSKETVSVSLQPGSSRASKTAPVHKPAAPSEEKKPETAVSRLQRREQLKKSNTLPTSVTVEISDSAPSAALVKDVTKRFSTPDAAPVSTEPAWLALAKRKAKAWSDCPQIIK
Protein
Cancer-related regulator of actin dynamics: Crad

Gene
crad
Protein
Cancer-related regulator of actin dynamics homolog
Organism
Danio rerio
Length
1079 amino acids
Function
Involved in epithelial cell integrity by acting on the maintenance of the actin cytoskeleton. Positively regulates the actin polymerization, by inhibiting the interaction of actin-capping proteins with actin.
Mass
123.615 kDa
Sequence
MSQENVSDKVRNIQKQIGHNIKFGQRPPSLRKSEGDEGSSDEEEVPQSPLRVLAQVENEPPETSAKEKSVSHDTVQHRTPVKSPRTKRPPPPGTIESINLDAVPQSVPRLDNTAAKHKLSVKPKNQRVSRKHRRFTQEFHEDDFSEIQEEFEKDEEVFDSSREDYGIIHGSKEDYEPTEKSQRQRFHEEEKEHLEIKKREQEEERKMEKHRRMIEEQRLEEEKRRRQEEERLQKVEEERKQREEEERKKREEEERRREEEERRLRHEEERKRQEEEERMKKEEEERKRAEEERRQQELLAERLRLEEERKREQEERRRKEEEEAEKRRIQELQEKRLREEEHRIREEERCRQEEAERKRLEEEERKRQLQEEKAGSTDPEWKRKAEELRWREMEERQRPFTFKVSSGEKQILFQKVNLTPVTPATGQQGETTAETWEGAKASSPGGPDSPTLSSSLYVPHTAILVTGAQLCGTAVNLDQIKDTACKSLLGLSEGKKAMGTPPSKSKTSPDRKSGKTKSVFESSLSTDQSNAAVLAEWASIRSKIFKGAEEGKYPEYTDQSRRPTSEDLNTVPFSHTNLRKTMSASAKFSITPARKKFADSNRNSEIFGQEEGVKTESAFTETSPVQKELPSLGTKVQSRGSKLVRIADEECMFAKDLPSFLVPSPPHGSPKSQRSESGSPIQAESEDSDTKDEDGEQKAQGGDEQPSPFGIKLRRTNYSLRFHNEQSAEKKKKRYSAGDSFEGVPVPLTAIDQDSDNSTLSEKSSPISPQQENIEFQTTVAPSKESRSKFSRSTLPLARTEGDNMSPKPPLYQKPATSPKPSEGATPLLSPLPKPGRRTSGDTISQRTGEAEQVATEQGSDHKGGVTASGPSQKSGQGEEDVKEKKSFFPSISIPWREKTDRRTELIKKEKPSLQARHSLDSSRSQDKETGPLWITLALQKQKGFREQQQNREERRNQREAKLAEKQARDRESAGSSPTEDKGNGSSSIISKHQTADENKRPDTLLARFERRDNLKKANTLPSSVTVEITDSTPSPPATKDVTKRFPPGDTTQVSTEPAWLALAKRKAKAWSDCPQIIK
Protein
Cancer-related regulator of actin dynamics homolog: crad