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cplane2

Gene
CPLANE2
Protein
Ciliogenesis and planar polarity effector 2
Organism
Homo sapiens
Length
258 amino acids
Function
Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
28.498 kDa
Sequence
MARPPVPGSVVVPNWHESAEGKEYLACILRKNRRRVFGLLERPVLLPPVSIDTASYKIFVSGKSGVGKTALVAKLAGLEVPVVHHETTGIQTTVVFWPAKLQASSRVVMFRFEFWDCGESALKKFDHMLLACMENTDAFLFLFSFTDRASFEDLPGQLARIAGEAPGVVRMVIGSKFDQYMHTDVPERDLTAFRQAWELPLLRVKSVPGRRLADGRTLDGRAGLADVAHILNGLAEQLWHQDQVAAGLLPNPPESAPE

Gene
Cplane2
Protein
Ciliogenesis and planar polarity effector 2
Organism
Mus musculus
Length
258 amino acids
Function
Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
28.422 kDa
Sequence
MARPPMHGSVIVPDWHETVEGKEYLACILRKNRRREFGLLERPVLPPSVVIDTASYKIFVSGKSGVGKTALVAKLAGLEVPIVHHETTGIQTTVVFWPAKLKASDCVVMFRFEFWDCGESALKKFDHMLPACKENADAFLFLFSFTDRASFEDLPGQLTRVAGEAPGLVKIVIGSKFDQYMHTDVPARDLTAFRQAWELPLFRVKSVPGRRLADGRTLDGRAGLADTAHVLNGLAEQLWHQDQVAAGLLPSSPESAPG

Gene
cplane2
Protein
Ciliogenesis and planar polarity effector 2
Organism
Xenopus tropicalis
Length
255 amino acids
Function
Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
28.362 kDa
Sequence
MALAEAPRPGPLMDPEWHGSPEGKEYLGCILRKKKRKFFGLIERPVLSPQLPADIASYKLFVCGRSGAGKTSFIAKLAGLEVPSMHHETTGIQTTCVYWPVRPTHSARPVIFRFQFWDCGEGALRKFDHILPACKEMADAVLFLFSFTDRSSFEDVPALISRTLGQEEDVARVVIGTKLDQYTHTDVTENDLRDFQRTWQLPVMRVRSVNGPRVAEGRGLDGRVGLVECAPVLNGLAEILWRRDQVIAGLVGGAD

Gene
cplane2
Protein
Ciliogenesis and planar polarity effector 2
Organism
Danio rerio
Length
252 amino acids
Function
Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity).
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
28.355 kDa
Sequence
MSVPPGSIIVSDWHRCPDSREFFSKILHKKRRRKFGLLEAPMMPPQMNVDLVRYKVFLSGKTGVGKSALAARLAGLDLPKMHYETTGIETTVVFWPVRLKESGRVLFFRFELWDCGESAMRRFDHMLLSCKEKVDAILFLFSFTDRGSFDDLTNQISRITEPSDRVVKLVVGTKFDLFMHTDVTESDVTHFQEVWGLPVFRVGGDVSAGLGEVAPLLNALAENLWHQDCMAASSVSISPQAALRETSSEIIV

Gene
cplane2
Protein
Ciliogenesis and planar polarity effector 2
Organism
Xenopus laevis
Length
249 amino acids
Function
Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells.
Similarity
Belongs to the small GTPase superfamily. Rab family.
Mass
27.867 kDa
Sequence
MSVTPVLDPEWQRSPEGLDYLSRVLRHNKRKFFGLIERPVLPPHLPADVAAYKVFVCGKSGVGKTSFIAKLSGLAVPSMHHETAGIQTTCMYWPVRPSGSARPVIFRFQFWDCGEGALRKFDHILPACKEKADAVLFLFSFTDRSSFEDVPALISRTLDQDEDVTRVVIGTKLDQYMHTDVTEDDLRDFQRTWQLPVMRVRSVNGPRMTDGRDLDGRAGLAECAPVLNGLAEILWHRDQVIAGLVGGAE