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comK

Gene
comK
Protein
Competence transcription factor
Organism
Bacillus subtilis (strain 168)
Length
192 amino acids
Function
A master regulator required for the expression of late competence genes including comC, comE, comG and the bdbDC operon (PubMed:8196543, PubMed:7783616, PubMed:11744713, PubMed:11918817, PubMed:11948146). Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes (PubMed:8196543, PubMed:7783616). Represses transcription of rok (PubMed:11849533). May repress expression of a few genes (PubMed:7783616).
Mass
22.43 kDa
Sequence
MSQKTDAPLESYEVNGATIAVLPEEIDGKICSKIIEKDCVFYVNMKPLQIVDRSCRFFGSSYAGRKAGTYEVTKISHKPPIMVDPSNQIFLFPTLSSTRPQCGWISHVHVKEFKATEFDDTEVTFSNGKTMELPISYNSFENQVYRTAWLRTKFQDRIDHRVPKRQEFMLYPKEERTKMIYDFILRELGERY